Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Denice C. Bay"'
Autor:
Branden S. J. Gregorchuk, Shelby L. Reimer, Carmine J. Slipski, Kieran A. Milner, Shannon L. Hiebert, Daniel R. Beniac, Timothy F. Booth, George G. Zhanel, Denice C. Bay
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Bacterial resistance to the antiseptic chlorhexidine (CHX), is a growing problem, recently shown to be caused by deleterious mutations to the phospholipid transport system component (mlaA) as well as efflux pump overexpression. Comparisons o
Externí odkaz:
https://doaj.org/article/901ea877c5674fbea2ac5931f10a97cb
Autor:
Branden S. J. Gregorchuk, Shelby L. Reimer, Daniel R. Beniac, Shannon L. Hiebert, Timothy F. Booth, Michelle Wuzinski, Brielle E. Funk, Kieran A. Milner, Nicola H. Cartwright, Ali N. Doucet, Michael R. Mulvey, Mazdak Khajehpour, George G. Zhanel, Denice C. Bay
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Biocides such as quaternary ammonium compounds (QACs) are potentially important contributors towards bacterial antimicrobial resistance development, however, their contributions are unclear due to a lack of internationally recognized biocide
Externí odkaz:
https://doaj.org/article/fec3e9dcd54c4ed3ab03bc9c3e187c7a
Autor:
Branden S. J. Gregorchuk, Shelby L. Reimer, Kari A. C. Green, Nicola H. Cartwright, Daniel R. Beniac, Shannon L. Hiebert, Timothy F. Booth, Patrick M. Chong, Garrett R. Westmacott, George G. Zhanel, Denice C. Bay
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Chlorhexidine (CHX) is an essential medicine used as a topical antiseptic in skin and oral healthcare treatments. The widespread use of CHX has increased concerns regarding the development of antiseptic resistance in Enterobacteria and its potential
Externí odkaz:
https://doaj.org/article/a1d940eaa8544e849c9f786bf62d0ae2
Autor:
Shelby L. Reimer, Daniel R. Beniac, Shannon L. Hiebert, Timothy F. Booth, Patrick M. Chong, Garrett R. Westmacott, George G. Zhanel, Denice C. Bay
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Outer membrane vesicles (OMVs) produced by Gram-negative bacteria are mediators of cell survival and pathogenesis by facilitating virulence factor dissemination and resistance to antimicrobials. Studies of OMV properties often focus on hypervesiculat
Externí odkaz:
https://doaj.org/article/6ef79e8f20924375a6c28f1bc3e9c7bc
Publikováno v:
Microbiology. 168
The small multidrug resistance (SMR) protein EmrE resides in the inner membrane and provides resistance against a wide range of antiseptic quaternary cationic compounds (QCCs) for the Gram-negative bacterium Escherichia coli . We have reported previo
Publikováno v:
Journal of visualized experiments : JoVE. (182)
Bacterial biofilms are difficult to eradicate from surfaces using conventional antimicrobial interventions. High-throughput 96-well microplate methods are frequently used to cultivate bacterial biofilms for rapid antimicrobial susceptibility testing
Autor:
George G. Zhanel, Christina Deng, Michael A. Zhanel, Heather J. Adam, Neal Irfan, Andrew Walkty, Joseph P. Lynch, James A. Karlowsky, Denice C. Bay, Frank Schweizer, Courtney K. Lawrence, Lionel A. Mandell, Alyssa R Golden, Liam Berry, Philippe Lagacé-Wiens, Sheryl A. Zelenitsky
Publikováno v:
Drugs. 81:233-256
Lefamulin is a novel oral and intravenous (IV) pleuromutilin developed as a twice-daily treatment for community-acquired bacterial pneumonia (CABP). It is a semi-synthetic pleuromutilin with a chemical structure that contains a tricyclic core of five
Autor:
Derek T. Tan, Michael R. Mulvey, George G. Zhanel, Denice C. Bay, Richard J. Reid-Smith, Nicol Janecko, George R. Golding
Publikováno v:
Anaerobe. 74
In this study, we isolated and molecularly characterized 10 (1.6%) C. difficile isolates from 644 commercially available raw meat samples. Molecular typing by PFGE and ribotyping revealed NAP and ribotypes commonly associated with human clinical case
Publikováno v:
Antimicrobial Agents and Chemotherapy
Qac efflux pumps from proteobacterial multidrug-resistant plasmids are integron encoded and confer resistance to quaternary ammonium compound (QAC) antiseptics; however, many are uncharacterized and misannotated. A survey of >2,000 plasmid-carried qa
Autor:
Denice C. Bay, Patrick Chong, Branden S. J. Gregorchuk, Shannon L. Hiebert, Timothy F. Booth, Daniel R. Beniac, George G. Zhanel, Shelby L. Reimer, Nicola H. Cartwright, Garrett Westmacott, Kari A. C. Green
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Chlorhexidine (CHX) is an essential medicine used as a topical antiseptic in skin and oral healthcare treatments. The widespread use of CHX has increased concerns regarding the development of antiseptic resistance in Enterobacteria and its potential