Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Denglei Ma"'
Autor:
Qing Bai, Enhua Shao, Denglei Ma, Binxuan Jiao, Seth D. Scheetz, Karen A. Hartnett-Scott, Vladimir A. Ilin, Elias Aizenman, Julia Kofler, Edward A. Burton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Progressive supranuclear palsy (PSP) is an incurable neurodegenerative disease characterized by 4-repeat (0N/4R)-Tau protein accumulation in CNS neurons. We generated transgenic zebrafish expressing human 0N/4R-Tau to investigate PSP pathoph
Externí odkaz:
https://doaj.org/article/8830819a9bf74daa9a3baec147b6c3a3
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 7, Pp 1454-1462 (2024)
Hypertension is a primary risk factor for the progression of cognitive impairment caused by cerebral small vessel disease, the most common cerebrovascular disease. However, the causal relationship between hypertension and cerebral small vessel diseas
Externí odkaz:
https://doaj.org/article/4ee361229c3a4709b16f89131866cae8
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 6, p 166 (2023)
Background: Synucleinopathies, which are major pathological features of Parkinson’s disease (PD), are characterized by misfolded aggregates of α-synuclein in the peripheral and central nervous system. Icariin (ICA) is the main active component of
Externí odkaz:
https://doaj.org/article/c7cef59f111a48de8767b29536434754
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Multiple sclerosis (MS) is an autoimmune and chronic inflammatory demyelinating disease of the central nervous system (CNS), which gives rise to focal lesion in CNS and cause physical disorders. Although environmental factors and susceptibility genes
Externí odkaz:
https://doaj.org/article/56d3ee872be6434a9a93a8866075481d
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
P301S transgenic mice are an animal model of tauopathy and Alzheimer’s disease (AD), exhibiting tau pathology and synaptic dysfunction. Cornel iridoid glycoside (CIG) is an active ingredient extracted from Cornus officinalis, a traditional Chinese
Externí odkaz:
https://doaj.org/article/b91757f495d24fecb74d30f41da9fca8
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Alzheimer’s disease (AD) involves the degeneration of cholinergic neurons in the basal forebrain. Neural stem cell (NSC) transplantation has emerged as a promising therapeutic approach for treating AD. Icariin (ICA) is the main active component in
Externí odkaz:
https://doaj.org/article/43e97eb98a6a417da506b681b841067f
Autor:
Mingyang Wang, Xin-Min Li, Denglei Ma, Lin Li, Zheng-yu Sun, Jie-wen Zhang, Lan Zhang, Cuicui Yang, Li-Hong Gu
Publikováno v:
Brain Research Bulletin. 174:141-152
Schizophrenia is a mental illness characterized by episodes of psychosis, apathy, social withdrawal, and cognitive impairment. White matter lesions and glutamatergic hypofunction are reported to be the key pathogeneses underlying the multiple clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1420bb328c066d85a71dd0bfc3d75320
https://doi.org/10.1016/j.brainresbull.2021.06.007
https://doi.org/10.1016/j.brainresbull.2021.06.007
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Background. Aging is an important risk factor for sporadic Alzheimer’s disease (AD) and other neurodegenerative diseases. Senescence-accelerated mouse-prone 8 (SAMP8) is used as an animal model for brain aging and sporadic AD research studies. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f33e43372cd8effe565743bac54392
https://doi.org/10.1155/2021/9920962
https://doi.org/10.1155/2021/9920962
Publikováno v:
Current Medical Science. 40:1031-1039
rTg4510 mice are transgenic mice expressing P301L mutant tau and have been developed as an animal model of tauopathies including Alzheimer's disease (AD). Besides cognitive impairments, rTg4510 mice also show abnormal hyperactivity behavior. Cornel i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0e6ef125d24da3cf215ad416473539
https://doi.org/10.1007/s11596-020-2284-z
https://doi.org/10.1007/s11596-020-2284-z
Autor:
Denglei Ma
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::110dfbc5cda52e070ccfd1ebdb2094f5
https://doi.org/10.1002/alz.055778
https://doi.org/10.1002/alz.055778