Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Dengguo Wei"'
Autor:
Ju Sun, Zhiyuan Huang, Lei Chen, Liangrong Guo, Yuxiang Wang, Yingxiang Deng, Guoyue Liu, Zi Wen, Dengguo Wei
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-11 (2024)
Abstract Porcine deltacoronavirus (PDCoV) is a newly emerging and special delta coronavirus, which infect mammals such as pigs, cattle and humans, as well as chickens and birds. Exploring RNA structures in the viral genome benefits the understanding
Externí odkaz:
https://doaj.org/article/d77b11534da14ca2912d88e300dab500
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract G-quadruplex (G4) is a four-stranded helical DNA secondary structure formed by guanine-rich sequence folding, and G4 has been computationally predicted to exist in a wide range of species. Substantial evidence has supported the formation of
Externí odkaz:
https://doaj.org/article/450442d20cb54c358f97869b42e83738
Autor:
Congbao Xie, Xianpeng Zhang, Wenyue Pei, Ju Sun, Hongqi Shang, Zhiyuan Huang, Mengxi Wang, Daozhong Wang, Guiqian Wang, Zhikun Gui, Sisi Liu, Feng Li, Dengguo Wei
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011796 (2023)
Plant viruses seriously disrupt crop growth and development, and classic protein-targeted antiviral drugs could not provide complete protection against them. It is urgent to develop antiviral compounds with novel targets. Photodynamic therapy shows p
Externí odkaz:
https://doaj.org/article/59769020894c4a7ebc336d05aae055dd
Autor:
Ping Zhang, Weicheng Sun, Dengguo Wei, Guodong Li, Jinsheng Xu, Zhuhong You, Bowei Zhao, Li Li
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background Emerging evidences show that Piwi-interacting RNAs (piRNAs) play a pivotal role in numerous complex human diseases. Identifying potential piRNA-disease associations (PDAs) is crucial for understanding disease pathogenesis at molec
Externí odkaz:
https://doaj.org/article/e3da4df733b5417bb370abfcfdf79026
Autor:
Hui Deng, Bowen Gong, Zhiquan Yang, Zhen Li, Huan Zhou, Yashu Zhang, Xiaohui Niu, Sisi Liu, Dengguo Wei
Publikováno v:
Molecules, Vol 24, Iss 4, p 774 (2019)
Guanine-rich sequences in the genomes of herpesviruses can fold into G-quadruplexes. Compared with the widely-studied G3-quadruplexes, the dynamic G2-quadruplexes are more sensitive to the cell microenvironment, but they attract less attention. Pseud
Externí odkaz:
https://doaj.org/article/d340a4895c7142e188ab71d3329cd1d6
Publikováno v:
New Journal of Chemistry. 46:8619-8625
An aptamer combined with a c-MYC-selective fluorophore could work as the fluorescent core of nucleic acid mimics of fluorescent proteins to locate and image functional biomolecules in cells.
Autor:
Hui Feng, Huang Wenbo, Dengguo Wei, Xu Lu, Junli Ye, Feng Li, Liu Sisi, Ke Shaoyong, Xianpeng Zhang, Wanneng Yang
Publikováno v:
Journal of Agricultural and Food Chemistry. 69:7458-7466
Difficulty in preventing crops from plant viruses urges to discover novel efficient antiviral chemicals, which is sped up by precise screening methods. Fluorescence-based methods have recently been applied as innovative and rapid tools for visually m
Publikováno v:
Biochimie.
Nucleic acids are an indispensable component in all known life forms. The biological processes are regulated by Nucleic acids, which associate to form special high-order structures. since the high-level structures of nucleic acids are related to gene
Autor:
Gary N. Parkinson, Hany I. Mohamed, Song Zibing, Chao Gao, Zhu Liu, Dengguo Wei, Mingqian Feng, Zhe Hu, Jieqin Ding, Haitao Hou, Shengzhen Xu, Shozeb Haider, Congbao Xie, Xin Chen
Publikováno v:
Nucleic Acids Research
A single G-quadruplex forming sequence from the human telomere can adopt six distinct topologies that are inter-convertible under physiological conditions. This presents challenges to design ligands that show selectivity and specificity towards a par
Publikováno v:
Analytica Chimica Acta. 1132:93-100
The development of highly sensitive fluorescence probes for telomeric multimeric G-quadruplexes has attracted extensive attention. However, few probes reported have exhibited selectivity for telomeric multimeric G-quadruplexes. Thus, it is challengin