Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Deng-Min Feng"'
Autor:
Deng-Min Feng1, Chen-Xia He1, Chao-Yu Miao2, Bin Lu3, Wen-Jun Wu3, You-Fa Ding4, Jing-Lun Xue1 jixue@fudan.ac.cn
Publikováno v:
Clinical & Experimental Pharmacology & Physiology. Dec2004, Vol. 31 Issue 12, p850-855. 6p.
Publikováno v:
Biomedicine & Pharmacotherapy. 63:129-135
To test the hypothesis that the persistent high level of transgene expression of linear DNA eliminating bacterial backbone (LDEBB) results from less cytokine induction in vivo. We systematically investigated the effect of circular DNA (C DNA), linear
Publikováno v:
FEBS Letters. 580:4346-4352
The success of Cre-mediated conditional gene targeting in liver of mice has until now depended on the generation of Cre recombinase transgenic mice or on viral-mediated transduction. Here, we sought to establish the feasibility of using hydrodynamic
Publikováno v:
Journal of Molecular Biology. 358:38-45
Adeno-associated virus (AAV) is a non-pathogenic virus and the only known eukaryotic virus capable of targeting human chromosome 19 for integration at a well-characterized AAVS1 site. Its site-specific integration is mediated by Rep68 and Rep78, vira
Autor:
Jihua Yao, You-Fa Ding, Jinglun Xue, Daru Lu, Haoming Chen, Chenxia He, Li Chen, Deng-Min Feng, Qi Shen, Weniun Wu
Publikováno v:
Chinese Science Bulletin. 48:790-795
Hydrodynamics-based administration via tail vein was used to deliver naked plasmid with human factor IX (hFIX) cDNA in 2.2 mL Ringer’s solution into mice within 7 s. The peak level of expression of hFIX was 2921 ng/mL in mouse plasma. The hFIX cDNA
Publikováno v:
Clinical and experimental pharmacologyphysiology. 31(12)
1. It has been demonstrated that the hydrodynamics-based procedure has high efficiency to deliver foreign genes into the liver. The widespread use of this procedure in gene function studies and as a treatment option for liver and other organ diseases
Autor:
Qi Shen, Deng-Min Feng, Wen-Jun Wu, Jihua Yao, Jinglun Xue, Ding Shi, Bin Lu, Chenxia He, You-Fa Ding, Haoming Chen, Daru Lu
Publikováno v:
World Journal of Gastroenterology. 10:567
AIM: Transfer and expression of insulin gene in vivo are an alternative strategy to improve glycemic control in type 1 diabetes. Hydrodynamics-based procedure has been proved to be very efficient to transfer naked DNA to mouse livers. The basal hepat