Výsledky vyhledávání - "Denes Medzihradszky"

Solid-Phase Synthesis of Adenosine Phosphopeptides as Potential Bisubstrate Inhibitors of Protein Kinases

Autor: Susan L. Chen, Bradford W. Gibson, George L. Kenyon, Denes Medzihradszky

Publikováno v: Journal of the American Chemical Society. 116:9413-9419

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ad41273e0c5dca01ca1fb791d931c35
https://doi.org/10.1021/ja00100a001

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The primary structure of fatty-acid-binding protein from nurse shark liver. Structural and evolutionary relationship to the mammalian fatty-acid-binding protein family

Autor: Bradford W. Gibson, Denes Medzihradszky, Katalin F. Medzihradszky, Nathan M. Bass, Zhonghua Yu, Alma L. Burlingame, S Kaur

Publikováno v: European Journal of Biochemistry. 203:327-339

The primary structure of a fatty-acid-binding protein (FABP) isolated from the liver of the nurse shark (Ginglymostoma cirratum) was determined by high-performance tandem mass spectrometry (employing multichannel array detection) and Edman degradatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa66a835f34ac7295478657bb1bbc85
https://doi.org/10.1111/j.1432-1033.1992.tb16553.x

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Synthetic HIV-2 protease cleaves the GAG precursor of HIV-1 with the same specificity as HIV-1 protease

Autor: Denes Medzihradszky, Ming S. Chen, Stephen F. Carr, Daniel V. Santit, John C. Wu, Kurt Jarnagin, Jim W. Barnett, Hardy W. Chan, Donald Yamashiro, Steven Kirsher, Joan Chow

Publikováno v: Archives of Biochemistry and Biophysics. 277:306-311

A 99-amino acid protein having the deduced sequence of the protease from human immunodeficiency virus type 2 (HIV-2) was synthesized by the solid phase method and tested for specificity. The folded peptide catalyzes specific processing of a recombina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5f369c181562e3dc406dd7f1be9c7f
https://doi.org/10.1016/0003-9861(90)90584-l

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Mass spectrometric characterization of a series of adenosylated peptides acting as bisubstrate analogs of protein kinases

Autor: Denes Medzihradszky, Wade M. Hines, Seppo Auriola, Bradford W. Gibson, George L. Kenyon

Publikováno v: Journal of the American Society for Mass Spectrometry. 5(5)

We are currently developing strategies to synthesize bisubstrate analogs as potential inhibitors of serine and tyrosine protein kinases; several such analogs have been synthesized. The initial target proteins were the cAMP dependent protein kinase (c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf99685e2a4805cebb849911c9919b2f
https://pubmed.ncbi.nlm.nih.gov/24222599

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