SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry.

Autor: Decaesteker B; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium. Bieke.Decaesteker@ugent.be.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium. Bieke.Decaesteker@ugent.be., Louwagie A; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Loontiens S; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., De Vloed F; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Bekaert SL; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Roels J; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Vanhauwaert S; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., De Brouwer S; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Sanders E; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Berezovskaya A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Denecker G; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., D'haene E; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Van Haver S; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Van Loocke W; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Van Dorpe J; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium.; Department of Pathology, Ghent University Hospital, Ghent, Belgium., Creytens D; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium.; Department of Pathology, Ghent University Hospital, Ghent, Belgium., Van Roy N; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Pieters T; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Van Neste C; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Fischer M; Department for Experimental Pediatric Oncology, and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne, Cologne, Germany., Van Vlierberghe P; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Roberts SS; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Schulte J; Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, 13353, Germany., Ek S; Department of Immunotechnology, Lund University, Lund, Sweden., Versteeg R; Department of Oncogenomics, Academic Medical Center, Amsterdam, 1105, AZ, The Netherlands., Koster J; Department of Oncogenomics, Academic Medical Center, Amsterdam, 1105, AZ, The Netherlands., van Nes J; Department of Oncogenomics, Academic Medical Center, Amsterdam, 1105, AZ, The Netherlands., Zimmerman M; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., De Preter K; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium., Speleman F; Department of Biomolecular medicine, Ghent University, Ghent, 9000, Belgium. Franki.Speleman@ugent.be.; Cancer Research Institute Ghent (CRIG), Ghent, 9000, Belgium. Franki.Speleman@ugent.be.

Publikováno v: Nature communications [Nat Commun] 2023 Mar 07; Vol. 14 (1), pp. 1267. Date of Electronic Publication: 2023 Mar 07.

Macrophages use different internalization mechanisms to clear apoptotic and necrotic cells.

Autor: Krysko, D V^1,2, Denecker, G², Festjens, N², Gabriels, S¹, Parthoens, E³, D'Herde, K¹, Vandenabeele, P² Peter.Vandenabeele@dmbr.UGent.be

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Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.

Autor: Denecker, G, Vercammen, D, Steemans, M, Vanden Berghe, T, Brouckaert, G, Van Loo, G, Zhivotovsky, B, Fiers, W, Grooten, J, Declercq, W, Vandenabeele, P

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Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential.

Autor: De Craene, B¹, Denecker, G¹, Vermassen, P¹, Taminau, J¹, Mauch, C², Derore, A³, Jonkers, J⁴, Fuchs, E⁵, Berx, G¹

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NAD⁺ enhancers as therapeutic agents in the cardiorenal axis.

Autor: Marín-Blázquez, Mariano¹ (AUTHOR), Rovira, Jordi^2,3 (AUTHOR), Ramírez-Bajo, María José^2,3 (AUTHOR), Zapata-Pérez, Rubén¹ (AUTHOR) rzapata@ucam.edu, Rabadán-Ros, Rubén¹ (AUTHOR) rrabadan@ucam.edu

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