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pro vyhledávání: '"Dendritic cell homeostasis"'
Akademický článek
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Autor:
Alessandra Castiglioni, Markus Brown, Jillian L. Astarita, Mark Z. Chen, Lucinda Tam, Richard Bourgon, Claudia X. Dominguez, Shilpa Keerthivasan, Cecile Chalouni, Wendy Sandoval, Viviana Cremasco, Xiumin Wu, Yeqing Angela Yang, Andrey S. Shaw, Frederic J. de Sauvage, Ira Mellman, Elaine E. Storm, Catherine B Carbone, Merone Roose-Girma, Zora Modrusan, Amber W. Wang, Akshay T. Krishnamurty, Yasin Senbabaoglu, Wyne P. Lee, Jonas Doerr, Maximilian Nitschké, Shannon J. Turley, Varun N. Kapoor, Ryan Lane, Sören Müller, Christine Moussion
Publikováno v:
Nature Immunology. 22:571-585
Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture and regulate lymphocyte compartmentalization, homeostasis, and innate and adaptive immunity in secondary lymphoid organs (SLOs). In the present study, w
Publikováno v:
Nature Immunology. 22:541-543
Single-cell technologies reveal the building blocks of secondary lymphoid organs, identifying Grem1(+) fibroblastic reticular cells (FRCs) as critical niche cells that contribute to resident dendritic cell homeostasis and T cell immunity.
Autor:
Hsueh Chun Wang, Kazunari K. Yokoyama, Shyh Shin Chiou, Li Wen Tseng, Shau Ku Huang, Chee Yin Chai, Hsin Ying Clair Chiou, Ming-Hong Lin, Li Ting Wang, Shih Hsien Hsu, Kwei Yan Liu, Shen-Nien Wang
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
We propose that beyond its role in WNT secretion, WLS/GPR177 (wntless, WNT ligand secretion mediator) acts as an essential regulator controlling protein glycosylation, endoplasmic reticulum (ER) homeostasis, and dendritic cell (DC)-mediated immunity.
Autor:
Harriet A. Purvis, Fiona Clarke, Anna B. Montgomery, Chloe Colas, Jack A. Bibby, Georgina H. Cornish, Xuezhi Dai, Diana Dudziak, David J. Rawlings, Rose Zamoyska, Pierre Guermonprez, Andrew P. Cope
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2020, 11, ⟨10.3389/fimmu.2020.00376⟩
Purvis, H A, Clarke, F, Montgomery, A B K, Colas, C, Bibby, J A, Cornish, G H, Dai, X, Dudziak, D, Rawlings, D J, Zamoyska, R, Guermonprez, P & Cope, A P 2020, ' Phosphatase PTPN22 regulates dendritic cell homeostasis and cDC2 dependent T cell responses ', Frontiers in immunology, vol. 11, 376 . https://doi.org/10.3389/fimmu.2020.00376
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Frontiers, 2020, 11, ⟨10.3389/fimmu.2020.00376⟩
Purvis, H A, Clarke, F, Montgomery, A B K, Colas, C, Bibby, J A, Cornish, G H, Dai, X, Dudziak, D, Rawlings, D J, Zamoyska, R, Guermonprez, P & Cope, A P 2020, ' Phosphatase PTPN22 regulates dendritic cell homeostasis and cDC2 dependent T cell responses ', Frontiers in immunology, vol. 11, 376 . https://doi.org/10.3389/fimmu.2020.00376
Frontiers in Immunology, Vol 11 (2020)
Dendritic cells (DCs) are specialized antigen presenting cells that instruct T cell responses through sensing environmental and inflammatory danger signals. Maintaining the homeostasis of the multiple functionally distinct conventional dendritic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8703d5ab661bc19e05f0db1faa29d9
https://opus4.kobv.de/opus4-fau/files/13275/fimmu-11-00376-g0001.tif
https://opus4.kobv.de/opus4-fau/files/13275/fimmu-11-00376-g0001.tif
Autor:
Lijun Fang, Song Chen, Xiaolei Sun, Tiantian Feng, Huifang Huang, Jingru Liu, Xiaoming Feng, Chunmin Fang, Yuechen Luo
Publikováno v:
Experimental Cell Research. 363:73-83
Dendritic cells (DCs) are pivotal to initiating adaptive immune response. Emerging evidence highlights important roles of tuberous sclerosis complex 1 (Tsc1) in DC development and activation. Our previous study also showed that Tsc1 expression in DCs
Autor:
Sheng Xia, Huimin Jin, Nannan Yan, Lu Cheng, Huazhang An, Cheng Yan, Mutian Han, Qixiang Shao, Xiaoming Zhou, Shuiyun Wu, Yetao Qiang, Tengfei Xiao
Publikováno v:
International Immunopharmacology. 40:1-10
Epidemiological studies have shown that fat rich western diet contributes to the high incidence of inflammatory bowel disease (IBD). Moreover, accumulated data indicated that fat dietary factor might promote the change of the composition and metaboli
Autor:
Taketo Yamada, Takeya Adachi, Hideyuki Saya, Eiji Sugihara, Masayuki Amagai, Stefania Pittaluga, Koichi Ikuta, Tetsuro Kobayashi, Keisuke Nagao
Publikováno v:
Nature medicine
The skin harbors a variety of resident leukocyte subsets that must be tightly regulated to maintain immune homeostasis. Hair follicles are unique structures in the skin that contribute to skin dendritic cell homeostasis through chemokine production.
Autor:
Liu, K.
Publikováno v:
Encyclopedia of Cell Biology
T cells are an essential element that regulates the balance in immunity, by killing infected cells, helping antibody formation and suppressing autoimmune responses. However, T cells are incapable of recognizing native antigens. Instead, they recogniz
Autor:
Divya Gupta, Ann-Hwee Lee, Thomas A. Caputo, Sarah E. Bettigole, Lora Hedrick Ellenson, Pedro C. Silberman, Alfredo Perales-Puchalt, Jose R. Conejo-Garcia, Kevin Holcomb, Laurie H. Glimcher, Melanie R. Rutkowski, Sahil Chopra, Minkyung Song, Sheng Zhang, Juan R. Cubillos-Ruiz
Publikováno v:
Cell. 161:1527-1538
SummaryDendritic cells (DCs) are required to initiate and sustain T cell-dependent anti-cancer immunity. However, tumors often evade immune control by crippling normal DC function. The endoplasmic reticulum (ER) stress response factor XBP1 promotes i