Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dendritic Cells/drug effects"'
Autor:
Alexander A. Navarini, Curdin Conrad, Alessio Mylonas, Anne-Karine Lapointe, Jeremy Di Domizio, Olivier Demaria, Michel Gilliet, Cyrine Belkhodja, Lars E. French, Maxime Vernez
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature communications, vol. 9, no. 1, pp. 25
Nature Communications
Nature communications, vol. 9, no. 1, pp. 25
Although anti-tumor necrosis factor (TNF) agents are highly effective in the treatment of psoriasis, 2–5% of treated patients develop psoriasis-like skin lesions called paradoxical psoriasis. The pathogenesis of this side effect and its distinction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbc7decb248c10970a313c075620f0f
https://doaj.org/article/180fc992d72e4fcbbf1d606055e86015
https://doaj.org/article/180fc992d72e4fcbbf1d606055e86015
Autor:
Daniel Schnepf, Nils Lycke, Valentina Bernasconi, Hans Henrik Gad, Jan Becker, Yakup Tanriver, Karolina Ebert, Rune Hartmann, Liang Ye, Peter Staeheli
Publikováno v:
Ye, L, Schnepf, D, Becker, J, Ebert, K, Tanriver, Y, Bernasconi, V, Gad, H H, Hartmann, R, Lycke, N & Staeheli, P 2019, ' Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin ', Nature Immunology, vol. 20, no. 5, pp. 593-601 . https://doi.org/10.1038/s41590-019-0345-x
Interferon-λ (IFN-λ) acts on mucosal epithelial cells and thereby confers direct antiviral protection. In contrast, the role of IFN-λ in adaptive immunity is far less clear. Here, we report that mice deficient in IFN-λ signaling exhibited impaire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ff9cbee59331ae55971b8a53ef7e1a
https://pure.au.dk/portal/da/publications/interferon-enhances-adaptive-mucosal-immunity-by-boosting-release-of-thymic-stromal-lymphopoietin(103ab490-cd68-4f02-8921-47100722608f).html
https://pure.au.dk/portal/da/publications/interferon-enhances-adaptive-mucosal-immunity-by-boosting-release-of-thymic-stromal-lymphopoietin(103ab490-cd68-4f02-8921-47100722608f).html
Autor:
Nina Suhartha Löwa, Priscilla S. Brunetto, Inès Mottas, Magdalena Priebe, Carole Bourquin, Sarah-Luise Abram, Nina Khanna, Anne-Kathrin Woischnig, Katharina M. Fromm, Jérôme Widmer
Publikováno v:
Nanomedicine : nanotechnology biology and medicine
Nanomedicine, Vol. 13, No 1 (2017) pp. 11-22
Nanomedicine, Vol. 13, No 1 (2017) pp. 11-22
The progression in the use of orthopedic implants has led to an increase in the absolute number of implant infections, triggering a search for more effective antibacterial coatings. Nanorattles have recently gained interest in biomedical applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cca32c9f47e9a5085571464eded4956
http://doc.rero.ch/record/288596/files/fro_asf.pdf
http://doc.rero.ch/record/288596/files/fro_asf.pdf
Publikováno v:
Scientific Reports
Scientific reports, vol. 7, pp. 43844
Scientific reports, vol. 7, pp. 43844
The inflammasome–IL-1 axis and type I interferons (IFNs) have been shown to exert protective effects upon respiratory tract infections. Conversely, IL-1 has also been implicated in inflammatory airway pathologies such as asthma and chronic obstruct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db7b72299d640486f2d0ab0a279b556
Publikováno v:
BIOORGANIC & MEDICINAL CHEMISTRY
We report the synthesis of a small series of 6"-triazol-1-yl-substituted α-GalCer analogues by late-stage conversion of the 6"-OH to an azide group, copper-catalyzed azide-alkyne cycloaddition and final deprotection. When evaluated for their capacit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbff980302a2172b479f59c5efa7474
https://doi.org/10.1016/j.bmc.2012.09.063
https://doi.org/10.1016/j.bmc.2012.09.063
Publikováno v:
Menon, M, Blair, P A, Isenberg, D A & Mauri, C 2016, ' A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus ', Immunity, vol. 44, no. 3, pp. 683-697 . https://doi.org/10.1016/j.immuni.2016.02.012
Immunity
Immunity
Summary Signals controlling the generation of regulatory B (Breg) cells remain ill-defined. Here we report an “auto”-regulatory feedback mechanism between plasmacytoid dendritic cells (pDCs) and Breg cells. In healthy individuals, pDCs drive the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6360c924dbe40ed812fed1bc6c4f32df
https://www.research.manchester.ac.uk/portal/en/publications/a-regulatory-feedback-between-plasmacytoid-dendritic-cells-and-regulatory-b-cells-is-aberrant-in-systemic-lupus-erythematosus(1d3ade0f-c5b6-4cc3-b03e-877898151a19).html
https://www.research.manchester.ac.uk/portal/en/publications/a-regulatory-feedback-between-plasmacytoid-dendritic-cells-and-regulatory-b-cells-is-aberrant-in-systemic-lupus-erythematosus(1d3ade0f-c5b6-4cc3-b03e-877898151a19).html
Autor:
Nipa Decroix, Anne Hosmalin, Jean-Pierre Jourdain, Anne-Sophie Liovat, Odile Launay, Christiane Deveau, Michaela Müller-Trutwin, Matthieu Goguet, Charles-Antoine Dutertre, Sonia Amraoui, Pierre Loulergue, Laurence Meyer, Vincent Feuillet, Séverine A. Degrelle, Annalisa DeRosa, Cécile Goujard, Yolande Richard, Lene Vimeux
Publikováno v:
Blood
Blood, American Society of Hematology, 2012, 120 (11), pp.2259-2268. ⟨10.1182/blood-2012-03-418681⟩
Blood, 2012, 120 (11), pp.2259-2268. ⟨10.1182/blood-2012-03-418681⟩
Blood, American Society of Hematology, 2012, 120 (11), pp.2259-2268. ⟨10.1182/blood-2012-03-418681⟩
Blood, 2012, 120 (11), pp.2259-2268. ⟨10.1182/blood-2012-03-418681⟩
HIV infects activated CD4+ T cells and induces their depletion. Progressive HIV infection leading to AIDS is fueled by chronic immune hyperactivation, mediated by inflammatory cytokines like TNFα. This has been related to intestinal epithelial damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb5a4137f647010c8abf343dbc7b070
https://doi.org/10.1182/blood-2012-03-418681
https://doi.org/10.1182/blood-2012-03-418681
Publikováno v:
Molecular Immunology, Vol. 47, No 14 (2010) pp. 2349-2358
NK cells express toll-like receptors (TLR) that recognize conserved pathogen or damage associated molecular patterns and play a fundamental role in innate immunity. Low molecular weight dextran sulfate (DXS), known to inhibit the complement system, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3055223e8dff5fd5264a3084cbd4e20d
https://doi.org/10.1016/j.molimm.2010.05.284
https://doi.org/10.1016/j.molimm.2010.05.284
Autor:
Alan R. Prescott, Colin Watts, John M. Lucocq, Emma M. King, Zhongjun Zhou, Christian Gawden-Bone
Publikováno v:
Journal of Cell Science. 123:1427-1437
Podosomes are spot-like actin-rich structures formed at the ventral surface of monocytic and haematopoietic cells. Podosomes degrade extracellular matrix and are proposed to be involved in cell migration. A key question is whether podosomes form prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d05b8d79dec966fd369103f8dc3ff92
https://doi.org/10.1242/jcs.056515
https://doi.org/10.1242/jcs.056515
Autor:
Isabelle Angers, Stephen J. Galli, Adam Flaczyk, Salman T. Qureshi, Lothar Vogel, Ingo Spreitzer, Nicolas Gaudenzio, Sonja Wolfheimer, Stefan Schülke, B. Löschner, Mindy Tsai, Stephan Scheurer, Stefan Vieths
Publikováno v:
Allergy
Allergy, Wiley, 2015, 70 (10), pp.1259-1268. ⟨10.1111/all.12675⟩
Allergy, Wiley, 2015, 70 (10), pp.1259-1268. ⟨10.1111/all.12675⟩
Background Monophosphoryl lipid A (MPLA), a nontoxic TLR4 ligand derived from lipopolysaccharide (LPS), is used clinically as an adjuvant in cancer, hepatitis, and malaria vaccines and in allergen-specific immunotherapy. Nevertheless, its cell-activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead28381c905416c0cb2ec75c2a88011
https://pubmed.ncbi.nlm.nih.gov/26081583
https://pubmed.ncbi.nlm.nih.gov/26081583