Výsledky vyhledávání - "Dendrites/drug effects"

Effect of Ketamine on Dendritic Arbor Development and Survival of Immature GABAergic Neurons In Vitro

Autor: Laszlo Vutskits, Eduardo Gascon, Edömer Tassonyi, Jozsef Zoltan Kiss

Publikováno v: Review of Economic Dynamics, Vol. 91, No 2 (2006) pp. 540-549

Ketamine, a noncompetitive antagonist of the N-methyl-D-aspartate type of glutamate receptors, was reported to induce neuronal cell death when administered to produce anesthesia in young rodents and monkeys. Subanesthetic doses of ketamine, as adjuva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e2c3eb4d59753a5f78b2f2805f52c2
http://doc.rero.ch/record/298328/files/kfj180.pdf

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Silent synapses generate sparse and orthogonal action potential firing in adult-born hippocampal granule cells

Autor: Josef Bischofberger, Nicolas Toni, Stefanie Heigele, Charlotte Schmidt-Salzmann, Sébastien Sultan, Liyi Li

Publikováno v: eLife, Vol 6 (2017)
eLife, vol. 6, pp. e23612
eLife

In adult neurogenesis young neurons connect to the existing network via formation of thousands of new synapses. At early developmental stages, glutamatergic synapses are sparse, immature and functionally 'silent', expressing mainly NMDA receptors. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c8ece4563131045f7de155c1f8b2da
https://elifesciences.org/articles/23612

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Dendritic backpropagation and synaptic plasticity in the mormyrid electrosensory lobe

Autor: Yoshiko Sugawara, E. van de Burg, Shun-ichi Kuwana, Kirsty Grant, Jacob Engelmann, Joao Bacelo, M. de Ruijters

Publikováno v: Journal of Physiology-Paris. 102:233-245

This study is concerned with the origin of backpropagating action potentials in GABAergic, medium ganglionic layer neurones (MG-cells) of the mormyrid electrosensory lobe (ELL). The characteristically broad action potentials of these neurones are req

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2f6376e285c27b5e7a4591c9176f36
https://doi.org/10.1016/j.jphysparis.2008.10.004

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Clinically Relevant Concentrations of Propofol but Not Midazolam Alter In Vitro Dendritic Development of Isolated γ-Aminobutyric Acid-positive Interneurons

Autor: Edömer Tassonyi, Laszlo Vutskits, Jozsef Zoltan Kiss, Eduardo Gascon

Publikováno v: Anesthesiology, Vol. 102, No 5 (2005) pp. 970-976

Background Recent laboratory studies showed that exposure to supraclinical concentrations of propofol can induce cell death of immature neurons. However, no data are available regarding the effects of clinically relevant concentrations of this agent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5af8c8ff1ce5634b9a17675e613467
https://doi.org/10.1097/00000542-200505000-00016

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Sequential activation of p75 and TrkB is involved in dendritic development of subventricular zone-derived neuronal progenitorsin vitro

Autor: Eduardo Gascon, M. J. Barral-Moran, Laszlo Vutskits, Huanxiang Zhang, P. J. Kiss, Christophe Mas, Jozsef Zoltan Kiss

Publikováno v: European Journal of Neuroscience, Vol. 21, No 1 (2005) pp. 69-80

Dendritic arbor development of subventricular zone-derived interneurons is a critical step in their integration into functional circuits of the postnatal olfactory bulb. However, the mechanism and molecular control of this process remain unknown. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9118173b6f644b9e0874c6274186e1
https://doi.org/10.1111/j.1460-9568.2004.03849.x

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Miniature synaptic events maintain dendritic spines via AMPA receptor activation

Autor: Scott M. Thompson, R A McKinney, Beat H. Gähwiler, R Dürr, Marco Capogna

Publikováno v: McKinney, R A, Capogna, M, Dürr, R, Gähwiler, B H & Thompson, S M 1999, ' Miniature synaptic events maintain dendritic spines via AMPA receptor activation ', Nature Neuroscience, vol. 2, no. 1, pp. 44-9 . https://doi.org/10.1038/4548

We investigated the influence of synaptically released glutamate on postsynaptic structure by comparing the effects of deafferentation, receptor antagonists and blockers of glutamate release in hippocampal slice cultures. CA1 pyramidal cell spine den

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7c936867831ae3ad8ff35338ebf319
https://doi.org/10.1038/4548

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Estradiol promotes spine growth and synapse formation without affecting pre-established networks

Autor: Pablo Mendez, Dominique Muller, Luis M. Garcia-Segura

Publikováno v: Hippocampus
Hippocampus, Vol. 21, No 12 (2011) pp. 1263-7
Digital.CSIC. Repositorio Institucional del CSIC
instname

Estrogens regulate dendritic spine density, but the mechanism and significance of this effect for brain networks remain unknown. We used repetitive imaging over several days to investigate how 17β-estradiol affected the turnover and long-term behavi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25da74e106230d7d05f36b6074a86b89
http://hdl.handle.net/10261/61554

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AS601245, a c-Jun NH2-terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils

Autor: S, Carboni, U, Boschert, P, Gaillard, J-P, Gotteland, J-Y, Gillon, P-A, Vitte

Publikováno v: British Journal of Pharmacology, Vol. 153, No 1 (2008) pp. 157-163

Based on their proven ability, in animal models of stroke, to reduce damage to brain grey matter, many drugs have been tested in clinical trials but without success. Failure to save axons from injury and to protect functional outcome has been propose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bd6daf2274e87e9af3c7954965c637e5
https://archive-ouverte.unige.ch/unige:89899

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Etomidate reduces initiation of backpropagating dendritic action potentials: implications for sensory processing and synaptic plasticity during anesthesia

Autor: Joao Bacelo, Leonel Gómez, Jacob Engelmann, Erwin H. van den Burg, Kirsty Grant

Publikováno v: Journal of neurophysiology. 97(3)

Anesthetics may induce specific changes that alter the balance of activity within neural networks. Here we describe the effects of the GABAAreceptor potentiating anesthetic etomidate on sensory processing, studied in a cerebellum-like structure, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f259416cf140a9c6d7fcefbeebd165
https://pubmed.ncbi.nlm.nih.gov/17202233

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Low concentrations of ketamine initiate dendritic atrophy of differentiated GABAergic neurons in culture

Autor: Gael Potter, Laszlo Vutskits, Eduardo Gascon, Jozsef Zoltan Kiss, Edömer Tassonyi

Publikováno v: Toxicology, Vol. 234, No 3 (2007) pp. 216-226

Administration of subanesthetic concentrations of ketamine, a noncompetitive antagonist of the N-methyl-d-aspartate (NMDA) type of glutamate receptors, is a widely accepted therapeutic modality in perioperative and chronic pain management. Although e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb9f57ccfff1cbcc67af97ef270e0fc
https://archive-ouverte.unige.ch/unige:10508

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