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Autor:
Allison K. Martin, Charles A. Dinarello, Morgan K. Collins, Amy S. McKee, Andrew P. Fontenot, Denay J.K. Richards, Morgan F. Wade, Douglas G. Mack
Publikováno v:
The Journal of Immunology. 201:2232-2243
Metal-induced hypersensitivity is driven by dendritic cells (DCs) that migrate from the site of exposure to the lymph nodes, upregulate costimulatory molecules, and initiate metal-specific CD4+ T cell responses. Chronic beryllium disease (CBD), a lif