A PRE loop at the daclocus acts as a topological chromatin structure that restricts and specifies enhancer–promoter communication

Autor: Denaud, Sandrine, Bardou, Marion, Papadopoulos, Giorgio-Lucio, Grob, Stefan, Di Stefano, Marco, Sabarís, Gonzalo, Nollmann, Marcelo, Schuettengruber, Bernd, Cavalli, Giacomo

Publikováno v: Nature Structural and Molecular Biology; December 2024, Vol. 31 Issue: 12 p1942-1954, 13p

A PRE loop at the dac locus acts as a topological chromatin structure that restricts and specifies enhancer-promoter communication.

Autor: Denaud S; Institute of Human Genetics, UMR9002 CNRS, University of Montpellier, Montpellier, France., Bardou M; Centre de Biologie Structurale, IUMR5048 CNRS, INSERM U1054, University of Montpellier, Montpellier, France., Papadopoulos GL; Institute of Human Genetics, UMR9002 CNRS, University of Montpellier, Montpellier, France., Grob S; Department of Plant and Microbial Biology and Zurich-Basel Plant Science Center, University of Zurich, Zurich, Switzerland., Di Stefano M; Institute of Human Genetics, UMR9002 CNRS, University of Montpellier, Montpellier, France., Sabarís G; Institute of Human Genetics, UMR9002 CNRS, University of Montpellier, Montpellier, France., Nollmann M; Centre de Biologie Structurale, IUMR5048 CNRS, INSERM U1054, University of Montpellier, Montpellier, France., Schuettengruber B; Institute of Human Genetics, UMR9002 CNRS, University of Montpellier, Montpellier, France. bernd.schuttengruber@igh.cnrs.fr., Cavalli G; Institute of Human Genetics, UMR9002 CNRS, University of Montpellier, Montpellier, France. giacomo.cavalli@igh.cnrs.fr.

Publikováno v: Nature structural & molecular biology [Nat Struct Mol Biol] 2024 Dec; Vol. 31 (12), pp. 1942-1954. Date of Electronic Publication: 2024 Aug 16.