Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Denan Zhang"'
Autor:
Junpeng Cheng, Meizhu Xiao, Qingkang Meng, Min Zhang, Denan Zhang, Lei Liu, Qing Jin, Zhijin Fu, Yanjiao Li, Xiujie Chen, Hongbo Xie
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Non-small cell lung cancer (NSCLC) is a prevalent and heterogeneous disease with significant genomic variations between the early and advanced stages. The identification of key genes and pathways driving NSCLC tumor progression is
Externí odkaz:
https://doaj.org/article/99003a0899bc46deacc60cf3ed62f26f
Autor:
Hongzhe Ma, Guoqi Li, Diwei Huo, Yangguang Su, Qing Jin, Yangxu Lu, Yanyan Sun, Denan Zhang, Xiujie Chen
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
This study investigates the impact of Hashimoto’s thyroiditis (HT), an autoimmune disorder, on the papillary thyroid cancer (PTC) microenvironment using a dataset of 140,456 cells from 11 patients. By comparing PTC cases with and without HT, we ide
Externí odkaz:
https://doaj.org/article/98877b2ba6234790ac802b04703738a4
Autor:
Ying Wang, Yangguang Su, Kairui Zhao, Diwei Huo, Zhenshun Du, Zhiju Wang, Hongbo Xie, Lei Liu, Qing Jin, Xuekun Ren, Xiujie Chen, Denan Zhang
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34244- (2024)
At the beginning of the ''Disease X'' outbreak, drug discovery and development are often challenged by insufficient and unbalanced data. To address this problem and maximize the information value of limited data, we propose a drug screening model, LG
Externí odkaz:
https://doaj.org/article/05119be3a5bf40ae808125db7d829789
Autor:
Zhiyi MOU, Chunyan DUAN, Yanyu LI, Denan ZHANG, Yingjie SUN, Qiumei TENG, Yunshuang CHEN, Yang CAO, Zihui WANG, Guangping XU
Publikováno v:
Guangxi Zhiwu, Vol 43, Iss 5, Pp 880-889 (2023)
To investigate the effects of different biochar applications on soil enzyme activities in Eucalyptus plantations in North Guangxi, and provide theoretical references for the rational application of biochar to Eucalyptus plantations. Based on field ex
Externí odkaz:
https://doaj.org/article/e66b7eb1784c45afa1af79800a581e9e
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Target therapy for cancer cell mutation has brought attention to several challenges in clinical applications, including limited therapeutic targets, less patient benefits, and susceptibility to acquired due to their clear biological mec
Externí odkaz:
https://doaj.org/article/f113f36d77e84be08c68aa4a870e6965
Autor:
Guoqi Li, Diwei Huo, Naifu Guo, Yi Li, Hongzhe Ma, Lei Liu, Hongbo Xie, Denan Zhang, Bo Qu, Xiujie Chen
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Long non-coding RNAs (lncRNAs) play an important role in the immune regulation of gastric cancer (GC). However, the clinical application value of immune-related lncRNAs has not been fully developed. It is of great significance to overcome
Externí odkaz:
https://doaj.org/article/4118947cc82544cc94c5306d8d76268a
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background Breast cancer (BC) is a complex disease with high heterogeneity, which often leads to great differences in treatment results. Current common molecular typing method is PAM50, which shows positive results for precision medicine; ho
Externí odkaz:
https://doaj.org/article/4b0b2148935c41708d0cd4932df82c3c
Autor:
Lei Liu, Zhuo Shao, Jiaxuan Lv, Fei Xu, Sibo Ren, Qing Jin, Jingbo Yang, Weifang Ma, Hongbo Xie, Denan Zhang, Xiujie Chen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide. Due to the lack of early diagnosis methods and warning signals of CRC and its strong heterogeneity, the determination of accurate treatments for CRC and the ident
Externí odkaz:
https://doaj.org/article/1fcee3b09279474fa3e225cf9c68c357
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
BackgroundThe analysis of cancer diversity based on a logical framework of hallmarks has greatly improved our understanding of the occurrence, development and metastasis of various cancers.MethodsWe designed Cancer Hallmark Genes (CHG) database which
Externí odkaz:
https://doaj.org/article/f1c82f69bcb747f48b84f1dd9dc654b3
Autor:
Lingxiang Wu, Xiujie Chen, Denan Zhang, Wubing Zhang, Lei Liu, Hongzhe Ma, Jingbo Yang, Hongbo Xie, Bo Liu, Qing Jin
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164542 (2016)
Analysis of gene sets has been widely applied in various high-throughput biological studies. One weakness in the traditional methods is that they neglect the heterogeneity of genes expressions in samples which may lead to the omission of some specifi
Externí odkaz:
https://doaj.org/article/2286474631d649ba92fca76455715090