Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dena M. Minning"'
Autor:
William P. Sheridan, Brian R. Taubenheim, Pravin L. Kotian, Dena M. Minning, Y.S. Babu, Donald F. Smee, Justin G. Julander, John D. Morrey, Shanta Bantia
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:6607-6614
No effective antiviral therapies are currently available to treat disease after infection with yellow fever virus (YFV). A Syrian golden hamster model of yellow fever (YF) was used to characterize the effect of treatment with BCX4430, a novel adenosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961ad009f00efd19a41112fd036950b6
https://doi.org/10.1128/aac.03368-14
https://doi.org/10.1128/aac.03368-14
Autor:
Brett P. Eaton, Shanta Bantia, Shelley P. Honnold, Gianluca Pegoraro, Rekha G. Panchal, Nicole L. Garza, Travis K. Warren, Sina Bavari, Brian R. Taubenheim, William P. Sheridan, Jay Wells, Lian Dong, Pravin L. Kotian, Kelly S. Stuthman, Xilin Chen, Sean A. Van Tongeren, Y.S. Babu, Dena M. Minning, Cary Retterer, Lisa S. Welch
Publikováno v:
Nature
A broad-spectrum antiviral small molecule is reported to act as an inhibitor of viral polymerase activity and is shown to be effective in protecting non-human primates from lethal filovirus infection when administered after exposure. Supplementary in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22ee30eec1bfc646ed2a5e4d14995a9
http://europepmc.org/articles/PMC7095208
http://europepmc.org/articles/PMC7095208
Publikováno v:
Best Practice & Research Clinical Haematology. 17:3-22
Thromboembolic disorders are a major cause of morbidity and mortality. As knowledge of the complex interactions between the vessel wall, platelets and coagulation and fibrinolytic enzyme systems increases, new avenues for more effective and safer the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e092de821bb30e4b69fca145924052
https://doi.org/10.1016/j.beha.2004.02.001
https://doi.org/10.1016/j.beha.2004.02.001
Autor:
Joseph Bonaventura, Dena M. Minning, Andrew J. Gow, Jonathan S. Stamler, Daniel E. Goldberg, Mark W. Dewhirst, Rod D. Braun
Publikováno v:
Nature. 401:497-502
The parasitic nematode Ascaris lumbricoides infects one billion people worldwide. Its perienteric fluid contains an octameric haemoglobin that binds oxygen nearly 25,000 times more tightly than does human haemoglobin. Despite numerous investigations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99fd2eddeca1a09ab4f5281e43960d4c
https://doi.org/10.1038/46822
https://doi.org/10.1038/46822
Autor:
Loretta J. Nastoupil, Dena M. Minning, John M. Timmerman, Nam H. Dang, Patricia A. Young, Michael Gresser
Publikováno v:
Journal of Clinical Oncology. 34:TPS3109-TPS3109
TPS3109Background: Interferon alpha (IFNα) has anti-proliferative and pro-apoptotic effects against many cancers, including NHL, and promotes both innate and adaptive anti-tumor immunity, but the c...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2cbb95f0c8548397cfccf6cbf83e32c
https://doi.org/10.1200/jco.2016.34.15_suppl.tps3109
https://doi.org/10.1200/jco.2016.34.15_suppl.tps3109
Autor:
Dena M. Minning, Raj Sachdev, Sanjay Khare, Sherie L. Morrison, Kristopher K Steward, John M. Timmerman, Reiko E. Yamada, Michael Gresser, Patricia A. Young
Publikováno v:
Blood. 126:2762-2762
Background: Interferon-alpha (IFNα) is a pleiotrophic cytokine with direct anti-tumor and immunostimulatory effects. Currently IFNα is approved for the treatment of multiple hematologic malignancies, including non-Hodgkin lymphoma (NHL). However, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a99e5d0f6eadc54b23b8a055401bb943
https://doi.org/10.1182/blood.v126.23.2762.2762
https://doi.org/10.1182/blood.v126.23.2762.2762
Publikováno v:
Women’s Issues in Thrombosis and Hemostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9689c02a30806bc1b65bb594d4981fd4
https://doi.org/10.4324/9780203306994_chapter_1
https://doi.org/10.4324/9780203306994_chapter_1
Autor:
Dena M. Minning, Daniel E. Goldberg
Publikováno v:
The Journal of biological chemistry. 273(49)
The oxygen-avid, homooctameric hemoglobin of Ascaris (AH) has an unusual structure. Each polypeptide consists of two tandem globin folds followed by a highly charged COOH-terminal tail that contains four direct repeats of His-Lys-Glu-Glu (HKEE). Dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8290433583915f6910aab18b373d5ce7
https://pubmed.ncbi.nlm.nih.gov/9830004
https://pubmed.ncbi.nlm.nih.gov/9830004