Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dena Ahmad"'
Autor:
Simon J. Johnston, Dena Ahmad, Mohammed A. Aleskandarany, Sasagu Kurozumi, Chris C. Nolan, Maria Diez-Rodriguez, Andrew R. Green, Emad A. Rakha
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background P38 mitogen activated protein kinase is an intermediary signal transduction factor with context-specific roles in breast cancer. Recent mechanistic studies add to the growing consensus that P38 is a tumour suppressor, and it may r
Externí odkaz:
https://doaj.org/article/3758fe8095cf420d90a08aa95b669c9c
Autor:
Stephen Chan, Dena Ahmad, Muslim L. Alabdullah, Paul M. Moseley, Emad A. Rakha, Srinivasan Madhusudan
Publikováno v:
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology. 39(4)
Ovarian cancer is associated with the highest mortality rate among gynaecologic malignancies. There is a need to refine the classification of ovarian cancer and identify novel targets. The mammalian target of rapamycin (mTOR) pathway has a crucial ro
Autor:
Mohamed R. Hamed, M. Layth Alabdullah, Vimla Band, Ian O. Ellis, Dena Ahmad, Ola H. Negm, Sameer Mirza, Emad A. Rakha, Andrew R. Green
Publikováno v:
Breast Cancer Research and Treatment
Background Mitogen-activated protein kinases (MAPKs) are signalling transduction molecules that have different functions and diverse behaviour in cancer. In breast cancer, MAPK is related to oestrogen receptor (ER) and HER2. Methods Protein expressio
Autor:
Eric C. Tom, Timothy Alan Bielecki, Matthew D. Storck, Sameer Mirza, Emad A. Rakha, Rokaya El Ansari, Dena Ahmad, Priyanka Arya, Insha Mushtaq, Bhopal Mohapatra, Hamid Band, Vimla Band
Publikováno v:
Cancer Research. 78:2517-2517
Epidermal growth factor receptor (EGFR) is a prototype receptor tyrosine kinase and serves as an oncogene in a variety of solid tumors. Its surface expression is dynamically regulated, and display of an activation-competent cell surface pool is an es
Autor:
Patrick J. Tighe, Emad A. Rakha, Andrew R. Green, Christopher C. Nolan, Abir A. Muftah, Ola H. Negm, Ian O. Ellis, Maria Diez-Rodriguez, Mohammed A. Aleskandarany, Dena Ahmad, Mohamed R. Hamed
Publikováno v:
Breast cancer research and treatment. 155(1)
Reverse Phase Protein Array (RPPA) represents a sensitive and high-throughput technique allowing simultaneous quantitation of protein expression levels in biological samples. This study aimed to confirm the ability of RPPA to classify archival formal