Supporting Information Homotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells

Autor: Denèfle, Thomas, Pramil, Elodie, Gómez-Morales, Luis, Levasseur, Mikail, Lardé, Eva, Newton, Clara, Herry, Kenny, Herbi, Linda, Lamotte, Yann, Odile, Estelle, Ancellin, Nicolas, Grondin, Pascal, Martinez-Torres, Ana-Carolina, Viviani, Fabrice, Merle-Béral, Hélène, Lequin, Olivier, Susin, Santos, Karoyan, Philippe

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (17), pp.7656-7668. ⟨10.1021/acs.jmedchem.9b00024⟩

International audience; In order to optimize the potency of the first serum-stable peptide agonist of CD47 (PKHB1) in triggering regulated cell death of cancer cells, we designed a maturation process aimed to mimic the trimeric structure of the throm

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https://hal.sorbonne-universite.fr/hal-02367977/document

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CD47 agonist peptide PKHB1 induces immunogenic cell death in T‐cell acute lymphoblastic leukemia cells.

Autor: Uscanga‐Palomeque, Ashanti Concepción, Calvillo‐Rodríguez, Kenny Misael, Gómez‐Morales, Luis, Lardé, Eva, Denèfle, Thomas, Caballero‐Hernández, Diana, Merle‐Béral, Hélène, Susin, Santos A., Karoyan, Philippe, Martínez‐Torres, Ana Carolina, Rodríguez‐Padilla, Cristina

Publikováno v: Cancer Science; Jan2019, Vol. 110 Issue 1, p256-268, 13p

Homotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells

Autor: Denèfle, Thomas, Pramil, Elodie, Gómez-Morales, Luis, Levasseur, Mikail D., Lardé, Eva, Newton, Clara, Herry, Kenny, Herbi, Linda, Lamotte, Yann, Odile, Estelle, Ancellin, Nicolas, Grondin, Pascal, Martinez-Torres, Ana-Carolina, Viviani, Fabrice, Merle-Beral, Hélène, Lequin, Olivier, Susin, Santos A., Karoyan, Philippe

Publikováno v: Journal of Medicinal Chemistry; 20240101, Issue: Preprints