A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders

Autor: Fischer, Patrick D., Papadopoulos, Evangelos, Dempersmier, Jon M., Wang, Zi-Fu, Nowak, Radosław P., Donovan, Katherine A., Kalabathula, Joann, Gorgulla, Christoph, Junghanns, Pierre P.M., Kabha, Eihab, Dimitrakakis, Nikolaos, Petrov, Ognyan I., Mitsiades, Constantine, Ducho, Christian, Gelev, Vladimir, Fischer, Eric S., Wagner, Gerhard, Arthanari, Haribabu

Publikováno v: In European Journal of Medicinal Chemistry 5 July 2021 219

Epigenetic Regulation of the Thermogenic Adipose Program

Autor: Sambeat, Audrey, Gulyaeva, Olga, Dempersmier, Jon, Sul, Hei Sook

Publikováno v: In Trends in Endocrinology & Metabolism January 2017 28(1):19-31

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New Transcriptional Regulators of Non-shivering Thermogenesis

Autor: Dempersmier, Jon Michael

Publikováno v: Dempersmier, Jon Michael. (2015). New Transcriptional Regulators of Non-shivering Thermogenesis. UC Berkeley: Comparative Biochemistry. Retrieved from: http://www.escholarship.org/uc/item/0cf4h6j1

Unlike white adipose tissue (WAT), which stores excess energy as triglycerides, brown adipose tissue (BAT) burns fatty acids and glucose to produce heat. The thermogenic ability of BAT is due to the specialized inner mitochondrial proton transporter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::32e32598320783caed93d137349d7c12
http://www.escholarship.org/uc/item/0cf4h6j1

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