C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection.

Autor: Desai JV; Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy & Infectious Diseases, NIH, Bethesda, MD, USA., Kumar D; Immunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA; Departments of Biochemistry and Computer Science, Purdue University, West Lafayette, IN, USA., Freiwald T; Immunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA., Chauss D; Immunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA., Johnson MD; Duke Clinical Research Institute, Durham, NC, USA., Abers MS; Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy & Infectious Diseases, NIH, Bethesda, MD, USA., Steinbrink JM; Department of Medicine, Division of Infectious Diseases, Duke University, Durham, NC, USA., Perfect JR; Department of Medicine, Division of Infectious Diseases, Duke University, Durham, NC, USA., Alexander B; Department of Medicine, Division of Infectious Diseases, Duke University, Durham, NC, USA., Matzaraki V; Department of Genetics, University of Groningen, Groningen, the Netherlands., Snarr BD; Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy & Infectious Diseases, NIH, Bethesda, MD, USA., Zarakas MA; Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy & Infectious Diseases, NIH, Bethesda, MD, USA., Oikonomou V; Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy & Infectious Diseases, NIH, Bethesda, MD, USA., Silva LM; Oral Immunity and Infection Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD, USA., Shivarathri R; Center for Discovery & Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Beltran E; Complement and Inflammation Research Section, National Heart Lung and Blood Institute, NIH, Bethesda, MD, USA., Demontel LN; Complement and Inflammation Research Section, National Heart Lung and Blood Institute, NIH, Bethesda, MD, USA., Wang L; Departments of Biochemistry and Computer Science, Purdue University, West Lafayette, IN, USA., Lim JK; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Launder D; Department of Biological Sciences, University of Toledo, Toledo, OH, USA., Conti HR; Department of Biological Sciences, University of Toledo, Toledo, OH, USA., Swamydas M; Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy & Infectious Diseases, NIH, Bethesda, MD, USA., McClain MT; Department of Medicine, Division of Infectious Diseases, Duke University, Durham, NC, USA., Moutsopoulos NM; Oral Immunity and Infection Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD, USA., Kazemian M; Departments of Biochemistry and Computer Science, Purdue University, West Lafayette, IN, USA., Netea MG; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University, Nijmegen, the Netherlands., Kumar V; Department of Genetics, University of Groningen, Groningen, the Netherlands; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University, Nijmegen, the Netherlands., Köhl J; Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany., Kemper C; Complement and Inflammation Research Section, National Heart Lung and Blood Institute, NIH, Bethesda, MD, USA., Afzali B; Immunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA., Lionakis MS; Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology, National Institute of Allergy & Infectious Diseases, NIH, Bethesda, MD, USA. Electronic address: lionakism@mail.nih.gov.

Publikováno v: Cell [Cell] 2023 Jun 22; Vol. 186 (13), pp. 2802-2822.e22. Date of Electronic Publication: 2023 May 22.