Synergistic effect of peptide inhibitors derived from the extracellular and intracellular domain of αIIb subunit of integrin αIIbβ3 on platelet activation and aggregation

Autor: Alexia V. Gkourogianni, Klytaimnistra Kiouptsi, Vassiliki Koloka, Vassilios Moussis, Vassilios Tsikaris, Christilla Bachelot-Loza, Demokritos C. Tsoukatos

Publikováno v: Platelets, Vol 29, Iss 1, Pp 34-40 (2018)

αIIbβ3, the major platelet integrin, plays a central role in hemostasis and thrombosis. Upon platelet activation, conformation of αIIbβ3 changes and allows fibrinogen binding and, subsequently, platelet aggregation. It was previously shown that a

Externí odkaz: https://doaj.org/article/71ee734721a64c40843b69af0eefe17e

Molecular and mechanistic characterization of platelet-activating factor-like bioactivity produced upon LDL oxidation

Autor: Nicolaos Androulakis, Hervé Durand, Ewa Ninio, Demokritos C. Tsoukatos

Publikováno v: Journal of Lipid Research, Vol 46, Iss 9, Pp 1923-1932 (2005)

Oxidation of LDL is thought to be involved in both initiating and sustaining atherogenesis through the formation of proinflammatory lipids and the covalent modification of LDL particles. Platelet-activating factor (PAF; 1-0-alkyl-2-acetyl-sn-glycero-

Externí odkaz: https://doaj.org/article/67fd54438da94f3abb8a755732e61e49

Influence of dietary olive paste flour on the performance and oxidative stress in chickens raised in field conditions

Autor: Demokritos C. Tsoukatos, Constantinos C. Tellis, V Tsiouris, I Angelis, A Patsias, V Moulasioti, Me Boti, E Fotou, Vassilios Moussis

Publikováno v: Περιοδικό της Ελληνικής Κτηνιατρικής Εταιρείας; Τόμ. 72 Αρ. 3 (2021); 3239-3248
Journal of the Hellenic Veterinary Medical Society; Vol. 72 No. 3 (2021); 3239-3248

ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗ
Olive oil contains a variety of antioxidants, including vitamin E. Its consumption protects against oxidative stress, which is involved in many pathological conditions, affecting animals’ developmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588ea5ab6e5714eb45ca82804a3c3ef8
https://doi.org/10.12681/jhvms.28520

Synergistic effect of peptide inhibitors derived from the extracellular and intracellular domain of α

Autor: Alexia V, Gkourogianni, Klytaimnistra, Kiouptsi, Vassiliki, Koloka, Vassilios, Moussis, Vassilios, Tsikaris, Christilla, Bachelot-Loza, Demokritos C, Tsoukatos

Publikováno v: Platelets. 29(1)

α

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d8668e00ee458bf23c7562cdc03ec8b
https://pubmed.ncbi.nlm.nih.gov/28351192

Investigation of the role of adjacent amino acids to the 313–320 sequence of the αIIbsubunit on platelet activation and fibrinogen binding to αIIbβ3

Autor: Maria-Ruxandra Stanica, John V. Mitsios, Georgios Stamos, Foteini I. Rodis, Demokritos C. Tsoukatos, Alexandros D. Tselepis, Loukas D. Tsironis, Constantinos Sakarellos, Vassilios Tsikaris

Publikováno v: Platelets. 17:277-282

The platelet integrin receptor alphaIIbbeta3 plays a critical role in thrombosis and haemostasis by mediating interactions between platelets and several ligands, primarily fibrinogen. We have previously shown that the synthetic peptide YMESRADRKLAEVG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2498493f073d33527dfcf26a3ef8ee00
https://doi.org/10.1080/09537100500436713