Synergistic effect of peptide inhibitors derived from the extracellular and intracellular domain of αIIb subunit of integrin αIIbβ3 on platelet activation and aggregation

Autor: Alexia V. Gkourogianni, Klytaimnistra Kiouptsi, Vassiliki Koloka, Vassilios Moussis, Vassilios Tsikaris, Christilla Bachelot-Loza, Demokritos C. Tsoukatos

Publikováno v: Platelets, Vol 29, Iss 1, Pp 34-40 (2018)

αIIbβ3, the major platelet integrin, plays a central role in hemostasis and thrombosis. Upon platelet activation, conformation of αIIbβ3 changes and allows fibrinogen binding and, subsequently, platelet aggregation. It was previously shown that a

Externí odkaz: https://doaj.org/article/71ee734721a64c40843b69af0eefe17e

Inhibition of αIIbβ3 Ligand Binding by an αIIb Peptide that Clasps the Hybrid Domain to the βI Domain of β3.

Autor: Wen Hwa Lee, Elisabeth Schaffner-Reckinger, Demokritos C Tsoukatos, Kelly Aylward, Vassilios Moussis, Vassilios Tsikaris, Paraskevi Trypou, Marion Egot, Dominique Baruch, Nelly Kieffer, Christilla Bachelot-Loza

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0134952 (2015)

Agonist-stimulated platelet activation triggers conformational changes of integrin αIIbβ3, allowing fibrinogen binding and platelet aggregation. We have previously shown that an octapeptide, p1YMESRADR8, corresponding to amino acids 313-320 of the

Externí odkaz: https://doaj.org/article/02f6cc7527ea44f0a394fd7b92417bb0

Influence of dietary olive paste flour on the performance and oxidative stress in chickens raised in field conditions

Autor: Demokritos C. Tsoukatos, Constantinos C. Tellis, V Tsiouris, I Angelis, A Patsias, V Moulasioti, Me Boti, E Fotou, Vassilios Moussis

Publikováno v: Περιοδικό της Ελληνικής Κτηνιατρικής Εταιρείας; Τόμ. 72 Αρ. 3 (2021); 3239-3248
Journal of the Hellenic Veterinary Medical Society; Vol. 72 No. 3 (2021); 3239-3248

ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗ
Olive oil contains a variety of antioxidants, including vitamin E. Its consumption protects against oxidative stress, which is involved in many pathological conditions, affecting animals’ developmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588ea5ab6e5714eb45ca82804a3c3ef8
https://doi.org/10.12681/jhvms.28520

Synergistic effect of peptide inhibitors derived from the extracellular and intracellular domain of α

Autor: Alexia V, Gkourogianni, Klytaimnistra, Kiouptsi, Vassiliki, Koloka, Vassilios, Moussis, Vassilios, Tsikaris, Christilla, Bachelot-Loza, Demokritos C, Tsoukatos

Publikováno v: Platelets. 29(1)

α

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d8668e00ee458bf23c7562cdc03ec8b
https://pubmed.ncbi.nlm.nih.gov/28351192

Inhibition of αIIbβ3 Ligand Binding by an αIIb Peptide that Clasps the Hybrid Domain to the βI Domain of β3

Autor: Elisabeth Schaffner-Reckinger, Dominique Baruch, Demokritos C. Tsoukatos, Wen Hwa Lee, Kelly Aylward, Vassilios Moussis, Vassilios Tsikaris, Nelly Kieffer, Paraskevi Trypou, Marion Egot, Christilla Bachelot-Loza

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0134952 (2015)
PLoS ONE
PLoS ONE. San Franscisco, CA: Public Library of Science (2015).

Agonist-stimulated platelet activation triggers conformational changes of integrin αIIbβ3, allowing fibrinogen binding and platelet aggregation. We have previously shown that an octapeptide, p1YMESRADR8, corresponding to amino acids 313–320 of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d2dfb697dfaeaae4381f7d527f6739
http://europepmc.org/articles/PMC4557944?pdf=render