Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Demissie Alemayehu"'
Publikováno v:
Current Oncology, Vol 30, Iss 4, Pp 3964-3973 (2023)
A platform trial is a trial involving an innovative adaptive design with a single master protocol to efficiently evaluate multiple interventions. It offers flexible features such as dropping interventions for futility and adding new interventions to
Externí odkaz:
https://doaj.org/article/33fdd38bef8f4634b329a51404cc2481
Autor:
Lauren E. Dang, Susan Gruber, Hana Lee, Issa J. Dahabreh, Elizabeth A. Stuart, Brian D. Williamson, Richard Wyss, Iván Díaz, Debashis Ghosh, Emre Kıcıman, Demissie Alemayehu, Katherine L. Hoffman, Carla Y. Vossen, Raymond A. Huml, Henrik Ravn, Kajsa Kvist, Richard Pratley, Mei-Chiung Shih, Gene Pennello, David Martin, Salina P. Waddy, Charles E. Barr, Mouna Akacha, John B. Buse, Mark van der Laan, Maya Petersen
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Increasing emphasis on the use of real-world evidence (RWE) to support clinical policy and regulatory decision-making has led to a proliferation of guidance, advice, and frameworks from regulatory agencies, academia, professional societies, and indus
Externí odkaz:
https://doaj.org/article/1b066ab2c2c342e3b214a06e4b384ce1
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 106-112 (2021)
Increased use of azithromycin (AZ) in treating infections associated with coronavirus disease 2019 (COVID‐19) and reports of increased incidence of prolonged corrected QT (QTc) interval associated with AZ used with hydroxychloroquine prompted us to
Externí odkaz:
https://doaj.org/article/a614d481d60242c8bcf4c4c26c354a11
Publikováno v:
Perspectives in Clinical Research, Vol 4, Iss 4, Pp 221-226 (2013)
Aim: An effective clinical trial strategy to ensure patient safety as well as trial quality and efficiency involves an integrated approach, including prospective identification of risk factors, mitigation of the risks through proper study design and
Externí odkaz:
https://doaj.org/article/ba6cbde823b04a359bef4fe6683df17a
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 1, p e564 (2010)
Externí odkaz:
https://doaj.org/article/f8fffb13ec4e48b4a8f0da43db5a6667
Akademický článek
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Autor:
Demissie Alemayehu, Nigussie Dechassa
Publikováno v:
International Journal of Plant Production. 16:261-273
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef784b309bbb85c893204b245054fa19
https://doi.org/10.1007/s42106-022-00187-3
https://doi.org/10.1007/s42106-022-00187-3
Publikováno v:
Value in Health. 24:1643-1650
Objectives To compare finite mixture models with common survival models with respect to how well they fit heterogenous data used to estimate mean survival times required for cost-effectiveness analysis. Methods Publicly available overall survival (OS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce45430f4ebf5186cfa5aefe07675335
https://doi.org/10.1016/j.jval.2021.05.012
https://doi.org/10.1016/j.jval.2021.05.012
Publikováno v:
Statistics in Biopharmaceutical Research. 15:164-177
The goal of a phase I dose-finding trial is to determine the dose level of a new drug with acceptable toxicity. The optimal dose level is determined by sequentially allocating patients to increasin...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a78a28eb874b61cfd006edd74b09ed09
https://doi.org/10.1080/19466315.2021.1962402
https://doi.org/10.1080/19466315.2021.1962402
Publikováno v:
Clinical Pharmacology & Therapeutics. 111:373-381
Although the digital revolution has transformed many areas of human endeavor, pharmaceutical drug development has been relatively slow to embrace the emerging technologies to enhance efficiency and optimize value in clinical trials. The topic has gar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a31cc1c0d362b90ee8b8a194c581c6
https://doi.org/10.1002/cpt.2248
https://doi.org/10.1002/cpt.2248