Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Demirhan Kobat"'
Autor:
Chris Xu, Catharine G. Clark, Chris B. Schaffer, Ke Wang, Frank W. Wise, Demirhan Kobat, Nicholas G. Horton
Publikováno v:
Nature photonics
Two-photon fluorescence microscopy (2PM)1 enables scientists in various fields including neuroscience2,3, embryology4, and oncology5 to visualize in vivo and ex vivo tissue morphology and physiology at a cellular level deep within scattering tissue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92208119970e9cdfc0047760335d3992
https://doi.org/10.1038/nphoton.2012.336
https://doi.org/10.1038/nphoton.2012.336
Publikováno v:
Nature Photonics. 7:33-37
A parallel implementation of multifocal multiphoton modulation microscopy allows simultaneous phosphorescent lifetime and intensity imaging in vivo at speeds 100 times faster than conventional configurations. Three-dimensional imaging of a phosphores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f3905fe18c83212532d72c37fea6706
https://doi.org/10.1038/nphoton.2012.307
https://doi.org/10.1038/nphoton.2012.307
Autor:
David R. Rivera, Christopher M. Brown, Ina Pavlova, Watt W. Webb, Chris Xu, Demirhan Kobat, Dimitre G. Ouzounov
Publikováno v:
Proceedings of the National Academy of Sciences. 108:17598-17603
We present a compact and flexible endoscope (3-mm outer diameter, 4-cm rigid length) that utilizes a miniaturized resonant/nonresonant fiber raster scanner and a multielement gradient-index lens assembly for two-photon excited intrinsic fluorescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1736fa6f31d982cc5ce10e9e3149eca
https://doi.org/10.1073/pnas.1114746108
https://doi.org/10.1073/pnas.1114746108
Publikováno v:
Nature photonics
Multiphoton microscopy (MPM) is widely used for optical sectioning deep in scattering tissue, in vivo [1–2]. Phosphorescence lifetime imaging microscopy (PLIM) [3] is a powerful technique for obtaining biologically relevant chemical information thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::612a45e7d9f357cfc89c54b11eb3671d
https://pubmed.ncbi.nlm.nih.gov/23472061
https://pubmed.ncbi.nlm.nih.gov/23472061
Autor:
Scott S. Howard, Chris Xu, Eric R. DeLeon, Demirhan Kobat, Nicholas G. Horton, Kenneth R. Olsen, Adam Straub, Aamir A. Khan
Publikováno v:
Optics in the Life Sciences.
Multiphoton Microscopy and Phosphorescence Lifetime Microscopy are combined to produce full-frame lifetime resolved 3D images in vivo. Parallel excitation and acquisition of two-photon emission is achieved via a frequency multiplexed multi-foci excit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97b19d7bac2cfec861a782df14e2c5dd
https://doi.org/10.1364/ntm.2013.nth2b.1
https://doi.org/10.1364/ntm.2013.nth2b.1
Publikováno v:
Optics in the Life Sciences.
In vivo images of the mouse brain were recorded through an unthinned, intact skull using three-photon fluorescence microscopy at 1700 nm. Images of brain vasculature 900 μm below the surface of the skull were obtained.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd8b6a20991aab9e6b7e0825e835479c
https://doi.org/10.1364/ntm.2013.nt3b.3
https://doi.org/10.1364/ntm.2013.nt3b.3
Publikováno v:
Scopus-Elsevier
We demonstrate deep tissue three-photon microscopy at the new spectral window of 1700 nm. We imaged vasculature and RFP-tagged neurons up to 1 mm below the cortical surface, and RFP-tagged neurons below an unthinned skull.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e26ef1c031572675bd7dc7e2baae31b
https://doi.org/10.1364/biomed.2012.bsu2b.2
https://doi.org/10.1364/biomed.2012.bsu2b.2
Publikováno v:
Scopus-Elsevier
We demonstrate non-invasive, high-resolution, in vivo imaging of subcortical structures (the external capsule (EC) and hippocampus) within an intact mouse brain using three-photon fluorescence microscopy at the new spectral window of 1700 nm.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cafb404b8fafdc6234f3041bc3db7d
https://doi.org/10.1364/cleo_si.2012.cth5c.4
https://doi.org/10.1364/cleo_si.2012.cth5c.4
Publikováno v:
Journal of biomedical optics. 16(10)
Deep tissue in vivo two-photon fluorescence imaging of cortical vasculature in a mouse brain using 1280-nm excitation is presented. A record imaging depth of 1.6 mm in mouse cortex is achieved in vivo, approximately reaching the fundamental depth lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885615c3d4149afcc1de3dbef578f4d5
https://pubmed.ncbi.nlm.nih.gov/22029361
https://pubmed.ncbi.nlm.nih.gov/22029361
Publikováno v:
SPIE Proceedings.
A miniaturized scanning mechanism is a crucial component in the creation of endoscopes for microscopic imaging. Several groups have developed resonant sca nners (e.g., spiral or Lissajous scan pa ttern), but these suffer from limitations in non-unifo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::155f081dc05e83d9fb812cea8008b8d5
https://doi.org/10.1117/12.874176
https://doi.org/10.1117/12.874176