Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation

Autor: Fueyo-González, Francisco, McGinty, Mitchell, Ningoo, Mehek, Anderson, Lisa, Cantarelli, Chiara, Andrea Angeletti, Demir, Markus, Llaudó, Inés, Purroy, Carolina, Marjanovic, Nada, Heja, David, Sealfon, Stuart C., Heeger, Peter S., Cravedi, Paolo, Fribourg, Miguel

Publikováno v: In Immunity 8 March 2022 55(3):459-474

T Cell Expression of C5a Receptor 2 Augments Murine Regulatory T Cell (T REG ) Generation and T REG -Dependent Cardiac Allograft Survival.

Autor: A Verghese D; Nephrology Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Translational Transplant Research Center, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Demir M; Nephrology Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Translational Transplant Research Center, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Chun N; Nephrology Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Translational Transplant Research Center, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Fribourg M; Nephrology Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Cravedi P; Nephrology Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Translational Transplant Research Center, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Llaudo I; Nephrology Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Translational Transplant Research Center, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Woodruff TM; School of Biomedical Sciences, The University of Queensland, Brisbane St. Lucia, Brisbane, Queensland 4072, Australia; and., Yadav P; Nephrology Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Translational Transplant Research Center, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Lira SA; Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Medof ME; Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106., Heeger PS; Nephrology Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029; peter.heeger@mssm.edu.; Translational Transplant Research Center, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2018 Mar 15; Vol. 200 (6), pp. 2186-2198. Date of Electronic Publication: 2018 Feb 07.