Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Deming, Gou"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background RNA sequencing is a vital technique for analyzing RNA behavior in cells, but it often suffers from various biases that distort the data. Traditional methods to address these biases are typically empirical and handle them individua
Externí odkaz:
https://doaj.org/article/4d06436d76624014a77129ac9675522a
Autor:
Shujin Li, Jun Wang, Lin Qiu, Gaohui Fu, Yang Li, Qiang Su, Yiheng Zhu, Feilong Zhao, Jinglin Tian, Jinyong Huang, Yanqin Niu, Kang Kang, Deming Gou
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/f6d9a0247a0640f18a6399e6ef78b0f7
Autor:
Kang Kang, Jingjing Xiang, Xingshi Zhang, Yuting Xie, Mengting Zhou, Le Zeng, Junhao Zhuang, Jiahao Kuang, Yuanyuan Lin, Bozhe Hu, Qianmin Xiong, Qing Yin, Qiang Su, Xiaoyun Liao, Jun Wang, Yanqin Niu, Cuilian Liu, Jinglin Tian, Deming Gou
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-20 (2024)
Abstract Background Pulmonary hypertension (PH) is a progressive disease characterized by pulmonary vascular remodeling. Increasing evidence indicates that endothelial-to-mesenchymal transition (EndMT) in pulmonary artery endothelial cells (PAECs) is
Externí odkaz:
https://doaj.org/article/7f4efdfbb8a44e77858fecf9c64e3cc3
Autor:
Jun Wang, Jinyong Huang, Yunlong Hu, Qianwen Guo, Shasha Zhang, Jinglin Tian, Yanqin Niu, Ling Ji, Yuzhong Xu, Peijun Tang, Yaqin He, Yuna Wang, Shuya Zhang, Hao Yang, Kang Kang, Xinchun Chen, Xinying Li, Ming Yang, Deming Gou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Cell-free RNAs (cfRNAs) offer an opportunity to detect diseases from a transcriptomic perspective, however, existing techniques have fallen short in generating a comprehensive cell-free transcriptome profile. We develop a sensitive library p
Externí odkaz:
https://doaj.org/article/fd1ff641e7c94483a11ea6bc23bf2c4d
Altered cfDNA fragmentation profile in hypomethylated regions as diagnostic markers in breast cancer
Autor:
Jun Wang, Yanqin Niu, Ming Yang, Lirong Shu, Hongxian Wang, Xiaoqian Wu, Yaqin He, Peng Chen, Guocheng Zhong, Zhixiong Tang, Shasha Zhang, Qianwen Guo, Yun Wang, Li Yu, Deming Gou
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background Breast cancer, the most common malignancy in women worldwide, has been proven to have both altered plasma cell-free DNA (cfDNA) methylation and fragmentation profiles. Nevertheless, simultaneously detecting both of them for breast
Externí odkaz:
https://doaj.org/article/fa5b61b7e8794f5eb099a0178933fd6f
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 954 (2024)
Cardiac mesoderm enhancer-associated non-coding RNA (CARMN), an evolutionarily conserved long non-coding RNA (lncRNA), serves as the host gene for the miR143/145 cluster. It plays a crucial role in cardiovascular cell differentiation and the maintena
Externí odkaz:
https://doaj.org/article/d217307f810948e98b1c9047293f446c
Autor:
Jun Wang, Jiahao Kuang, Shasha Zhang, Zixin Liu, Qianwen Guo, Shujin Li, Lin Qiu, Gaohui Fu, Xinyang Lin, Jiayu Wu, Jinglin Tian, Jinyong Huang, Yanqin Niu, Kang Kang, Yunhui Zhang, Deming Gou
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108815- (2024)
Summary: Hypoxia-induced pulmonary hypertension (HPH) is a fatal cardiovascular disease characterized by an elevation in pulmonary artery pressure, resulting in right ventricular dysfunction and eventual heart failure. Exploring the pathogenesis of H
Externí odkaz:
https://doaj.org/article/a5aa86f579c347b6bb8c0e1ca52f3d52
Autor:
Jun Wang, Yanqin Niu, Lingjie Luo, Zefeng Lu, Qinghua Chen, Shasha Zhang, Qianwen Guo, Li Li, Deming Gou
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Background Hypoxia-induced pulmonary hypertension (HPH) is a lethal cardiovascular disease with the characteristic of severe remodeling of pulmonary vascular. Although a large number of dysregulated mRNAs, lncRNAs, circRNAs, and miRNAs relat
Externí odkaz:
https://doaj.org/article/8cac32475f93432d86f6dd89311c65e3
Autor:
Lei Yang, Jinglin Tian, Jun Wang, Jie Zeng, Ting Wang, Boya Lin, John Linneman, Li Li, Yanqin Niu, Deming Gou, Yunhui Zhang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundPulmonary hypertension (PH) is a lethal disease characterized by pulmonary vascular remodeling, which is mediated by the abnormal proliferation/migration of pulmonary arterial smooth muscle cells (PASMCs). Recent reports suggest the involve
Externí odkaz:
https://doaj.org/article/81b7785268dd473386a30d8429e01f98
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Blood circulating microRNAs (miRNAs) are proposed to be promising biomarkers for many neurodegenerative disorders, including Parkinson’s disease (PD). However, there is a lack of identified differentially expressed miRNAs in PD from differ
Externí odkaz:
https://doaj.org/article/575bb908b010497b9e21bb89ae948dba