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Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease.

Autor: Makhaeva GF; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Russia., Kovaleva NV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Russia., Rudakova EV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Russia., Boltneva NP; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Russia., Lushchekina SV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Russia.; Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia., Astakhova TY; Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia., Timokhina EN; Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia., Serebryakova OG; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Russia., Shchepochkin AV; Institute of Organic Synthesis, Russian Academy of Sciences, Yekaterinburg, Russia.; Department of Organic and Biomolecular Chemistry, Ural Federal University, Yekaterinburg, Russia., Averkov MA; Institute of Organic Synthesis, Russian Academy of Sciences, Yekaterinburg, Russia.; Department of Organic and Biomolecular Chemistry, Ural Federal University, Yekaterinburg, Russia., Utepova IA; Institute of Organic Synthesis, Russian Academy of Sciences, Yekaterinburg, Russia.; Department of Organic and Biomolecular Chemistry, Ural Federal University, Yekaterinburg, Russia., Demina NS; Institute of Organic Synthesis, Russian Academy of Sciences, Yekaterinburg, Russia., Radchenko EV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Russia.; Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia., Palyulin VA; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Russia.; Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia., Fisenko VP; Department of Pharmacology of the Institute of Biodesign and Complex System Modeling of Biomedical Science & Technology Park of Sechenov I.M., First Moscow State Medical University, Moscow, Russia., Bachurin SO; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Russia., Chupakhin ON; Institute of Organic Synthesis, Russian Academy of Sciences, Yekaterinburg, Russia.; Department of Organic and Biomolecular Chemistry, Ural Federal University, Yekaterinburg, Russia., Charushin VN; Institute of Organic Synthesis, Russian Academy of Sciences, Yekaterinburg, Russia.; Department of Organic and Biomolecular Chemistry, Ural Federal University, Yekaterinburg, Russia., Richardson RJ; Department of Pharmacology of the Institute of Biodesign and Complex System Modeling of Biomedical Science & Technology Park of Sechenov I.M., First Moscow State Medical University, Moscow, Russia.; Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, United States.; Department of Neurology, University of Michigan, Ann Arbor, MI, United States.; Center of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2023 Aug 09; Vol. 14, pp. 1219980. Date of Electronic Publication: 2023 Aug 09 (Print Publication: 2023).

Benzo[ b ]selenophene/thieno[3,2- b ]indole-Based N,S,Se-Heteroacenes for Hole-Transporting Layers.

Autor: Demina NS; I. A. Postovsky Institute of Organic Synthesis, Ural Division, Russian Academy of Sciences, S. Kovalevskoy Str., 22, Ekaterinburg 620990, Russia.; Ural Federal University Named after the First President of Russia B.N. Yeltsin, Mira Str., 19, Ekaterinburg 620002, Russia., Rasputin NA; I. A. Postovsky Institute of Organic Synthesis, Ural Division, Russian Academy of Sciences, S. Kovalevskoy Str., 22, Ekaterinburg 620990, Russia.; Ural Federal University Named after the First President of Russia B.N. Yeltsin, Mira Str., 19, Ekaterinburg 620002, Russia., Irgashev RA; I. A. Postovsky Institute of Organic Synthesis, Ural Division, Russian Academy of Sciences, S. Kovalevskoy Str., 22, Ekaterinburg 620990, Russia.; Ural Federal University Named after the First President of Russia B.N. Yeltsin, Mira Str., 19, Ekaterinburg 620002, Russia., Tameev AR; I. A. Postovsky Institute of Organic Synthesis, Ural Division, Russian Academy of Sciences, S. Kovalevskoy Str., 22, Ekaterinburg 620990, Russia.; A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninsky Prosp., 31, Bld.4, Moscow 119071, Russia., Nekrasova NV; A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninsky Prosp., 31, Bld.4, Moscow 119071, Russia., Rusinov GL; I. A. Postovsky Institute of Organic Synthesis, Ural Division, Russian Academy of Sciences, S. Kovalevskoy Str., 22, Ekaterinburg 620990, Russia.; Ural Federal University Named after the First President of Russia B.N. Yeltsin, Mira Str., 19, Ekaterinburg 620002, Russia., Nunzi JM; Department of Physics, Engineering Physics and Astronomy, Department of Chemistry, Queens University, 90 Bader Lane, Kingston, Ontario K7L-3N6, Canada., Charushin VN; I. A. Postovsky Institute of Organic Synthesis, Ural Division, Russian Academy of Sciences, S. Kovalevskoy Str., 22, Ekaterinburg 620990, Russia.; Ural Federal University Named after the First President of Russia B.N. Yeltsin, Mira Str., 19, Ekaterinburg 620002, Russia.

Publikováno v: ACS omega [ACS Omega] 2020 Apr 17; Vol. 5 (16), pp. 9377-9383. Date of Electronic Publication: 2020 Apr 17 (Print Publication: 2020).