Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

Autor: Lazar, AJ, McLellan, MD, Bailey, MH, Miller, CA, Appelbaum, EL, Cordes, MG, Fronick, CC, Fulton, LA, Fulton, RS, Mardis, ER, Schmidt, HK, Wong, W, Wilson, RK, Yellapantula, V, Radenbaugh, AJ, Hoadley, KA, Hayes, DN, Parker, JS, Wilkerson, MD, Auman, JT, Balu, S, Bodenheimer, T, Hoyle, AP, Jefferys, SR, Jones, CD, Lehmann, K-V, Meng, S, Mieczkowski, PA, Mose, LE, Perou, CM, Roach, J, Senbabaoglu, Y, Shi, Y, Simons, JV, Skelly, T, Soloway, MG, Tan, D, Veluvolu, U, Davis, IJ, Hepperla, AJ, Brohl, AS, Kasaian, K, Mungall, K, Sadeghi, S, Barthel, FP, Verhaak, R, Hu, X, Chibon, F, Cherniack, AD, Shih, J, Beroukhim, R, Meyerson, M, Cibulskis, C, Gabriel, SB, Saksena, G, Schumacher, SE, Gao, Q, Wyczalkowski, M, Bowlby, R, Robertson, AG, Ally, A, Balasundaram, M, Brooks, D, Carlsen, R, Chuah, E, Dhalla, N, Holt, RA, Jones, SJM, Lee, D, Li, I, Ma, Y, Marra, MA, Mayo, M, Moore, RA, Mungall, AJ, Schein, JE, Sipahimalani, P, Tam, A, Thiessen, N, Wong, T, Danilova, L, Cope, L, Baylin, SB, Bootwalla, MS, Lai, PH, Laird, PW, Maglinte, DT, Van Den Berg, DJ, Weisenberger, DJ, Wrangle, J, Drill, E, Shen, R, Iype, L, Reynolds, SM, Shmulevich, I, Yau, C, Armenia, J, Liu, EM, Benz, C, Pastore, A, Sanchez-Vega, F, Schultz, N, Akbani, R, Hegde, AM, Liu, W, Lu, Y, Mills, GB, Weinstein, JN, Roszik, J, Anur, P, Spellman, P, Abeshouse, A, Chen, H-W, Gao, J, Heins, Z, Kundra, R, Larsson, E, Ochoa, A, Sander, C, Socci, N, Zhang, H, Noble, MS, Heiman, DI, Kim, J, Chin, L, Getz, G, Cho, J, Defreitas, T, Frazer, S, Gehlenborg, N, Lawrence, MS, Lin, P, Meier, S, Voet, D, Byers, L, Diao, L, Gay, CM, Wang, J, Newton, Y, Cooper, LAD, Gutman, DA, Lee, S, Nalisnik, M, Bowen, J, Gastier-Foster, JM, Gerken, M, Helsel, C, Hobensack, S, Leraas, KM, Lichtenberg, TM, Ramirez, NC, Wise, L, Zmuda, E, Anderson, ML, Castro, P, Ittmann, M, Gordienko, E, Paklina, O, Setdikova, G, Raut, CP, Karlan, BY, Lester, J, Belyaev, D, Fulidou, V, Potapova, O, Voronina, O, Demetri, GD, Ramalingam, SS, Behera, M, Delman, K, Owonikoko, TK, Sica, GL, Boyd, J, Magliocco, A, Salner, A, Bennett, J, Iacocca, M, Swanson, P, Dottino, P, Kalir, T, Pereira, E, Akeredolu, T, Crain, D, Curley, E, Gardner, J, Mallery, D, Morris, S, Paulauskis, J, Penny, R, Shelton, C, Shelton, T, Thompson, E, Hoon, DB, Parfitt, J, Birrer, M, Karseladze, A, Mariamidze, A, Dao, F, Levine, DA, Olvera, N, Maki, RG, Bartlett, J, Eschbacher, J, Dubina, M, Mozgovoy, E, Fedosenko, K, Manikhas, G, Sekhon, H, Ramirez, N, Ingram, DR, Torres, KE, DiSaia, P, Godwin, AK, Godwin, EM, Kuo, H, Madan, R, Reilly, C, Adebamowo, C, Adebamowo, SN, Bocklage, T, Higgins, K, Martinez, C, Boice, L, Grilley-Olson, JE, Huang, M, Perou, AH, Thorne, LB, Rathmell, WK, Gutmann, DH, Singer, S, Chudamani, S, Liu, J, Lolla, L, Naresh, R, Pihl, T, Sun, Q, Wan, Y, Wu, Y, Felau, I, Zenklusen, JC, Demchok, JA, Ferguson, ML, Hutter, CM, Sofia, HJ, Tarnuzzer, R, Wang, Z, Yang, L, Zhang, JJ, Demicco, EG, Doyle, LA, Hornick, JL, Rubin, BP, de Rijn, MV, Baker, L, Riedel, RF, Ding, L, Ladanyi, M, Novak, JE, Van Tine, BA, Davis, LE, Grilley-Olsen, JE, Pollock, RE, Jones, KB, Martignetti, JA, Tong, P, Network, CGAR

Publikováno v: Lazar, AJ; McLellan, MD; Bailey, MH; Miller, CA; Appelbaum, EL; Cordes, MG; et al.(2017). Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas. CELL, 171(4), 950-+. doi: 10.1016/j.cell.2017.10.014. UCLA: Retrieved from: http://www.escholarship.org/uc/item/47j3z4n7

Summary Sarcomas are a broad family of mesenchymal malignancies exhibiting remarkable histologic diversity. We describe the multi-platform molecular landscape of 206 adult soft tissue sarcomas representing 6 major types. Along with novel insights int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c86ec3399a3a9a3d27362677c3acb09

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Epigenomic and Transcriptomic Profiling of Solitary Fibrous Tumors Identifies Site-Specific Patterns and Candidate Genes Regulated by DNA Methylation.

Autor: Beird HC; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Cloutier JM; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Gokgoz N; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital Toronto, Ontario, Canada., Eeles C; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Griffin AM; University of Toronto Musculoskeletal Oncology Unit, Division of Orthopaedic Surgery, Department of Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada., Ingram DR; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wani KM; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Segura RL; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Cohen L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ho C; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wunder JS; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital Toronto, Ontario, Canada; University of Toronto Musculoskeletal Oncology Unit, Division of Orthopaedic Surgery, Department of Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada., Andrulis IL; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital Toronto, Ontario, Canada; Department of Molecular Genetics Canada, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Futreal PA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Haibe-Kains B; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Vector Institute for Artificial Intelligence, Toronto, Ontario, Canada., Lazar AJ; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wang WL; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Przybyl J; Department of Surgery, McGill University & Cancer Research Program, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada., Demicco EG; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada. Electronic address: Elizabeth.demicco@sinaihealth.ca.

Publikováno v: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2024 Nov; Vol. 104 (11), pp. 102146. Date of Electronic Publication: 2024 Sep 30.

International Multicenter Retrospective Study From the Ultra-rare Sarcoma Working Group on Low-grade Fibromyxoid Sarcoma, Sclerosing Epithelioid Fibrosarcoma, and Hybrid Forms: Outcome of Primary Localized Disease.

Autor: Giani C; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Salawu A; Division of Medical Oncology and Hematology, Mount Sinai Hospital and Princess Margaret Cancer Centre, Toronto, Canada., Ljevar S; Unit of Biostatistics for Clinical Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Denu RA; Division of Cancer Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX., Napolitano A; Department of Medical Oncology, The Royal Marsden NHS and Institute of Cancer Research, London., Palmerini E; Osteoncology, Bone and Soft Tissue Sarcomas, and Innovative Therapies Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy., Connolly EA; Department of Medical Oncology, Chris O'Brien Lifehouse.; Faculty of Medicine & Health, University of Sydney, Sydney, Australia., Ogura K; Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan., Wong DD; Department of Anatomical Pathology, PathWest, Sir Charles Gairdner Hospital, Nedlands, WA, Australia., Scanferla R; Department of Orthopedics Oncology and Reconstructive Surgery, AOU Careggi, Florence, Italy., Rosenbaum E; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Bajpai J; Department of Medical Oncology, Tata Memorial Centre, Homi Bhabha National University, Mumbai, Maharashtra, India., Li ZC; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan., Bae S; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., D'Ambrosio L; Department of Medical Oncology, University of Turin, Turin, Italy., Bialick S; Department of Medical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, Coral Gables, FL., Wagner AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Lee ATJ; Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester., Koseła-Paterczyk H; Department of Medical Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Baldi GG; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Brunello A; Department of Oncology, Medical Oncology 1 Unit, Istituto Oncologico Veneto IOV - IRCCS, Padua, Italy., Lee YC; Department of Medical Oncology, Prince of Wales Hospital (POW), Randwick.; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, Australia., Loong HH; Department of Clinical Oncology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China., Boikos S; Department of Medical Oncology, MedStar Washington Hospital Center, Washington, DC., Campos F; Department of Medical Oncology, A.C.Camargo Cancer Center, São Paulo, Brazil., Cicala CM; Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), Barcelona., Maki RG; Department of Medical Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Hindi N; Department of Medical Oncology, Fundación Jimenez Diaz University Hospital and Villalba General Hospital, Madrid, Spain., Figura C; Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Almohsen SS; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada., Patel S; Division of Cancer Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX., Jones RL; Department of Medical Oncology, The Royal Marsden NHS and Institute of Cancer Research, London., Ibrahim T; Osteoncology, Bone and Soft Tissue Sarcomas, and Innovative Therapies Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy., Karim R; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, NSW Health Pathology, Sydney.; Faculty of Medicine and Health, The University of Sydney, NSW., Kawai A; Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan., Carey-Smith R; Department of Orthopaedic Surgery, Sir Charles Gairdner Hospital, Perth, WA., Boyle R; Orthopaedic Surgeon, Royal Prince Alfred Hospital, Faculty of Medicine, Sydney.; Health, Sydney University, School of Medicine University of Notre Dame, Sydney, NSW, Australia., Taverna SM; Technology Transfer Office, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Lazar AJ; Department of Pathology and Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX., Demicco EG; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada., Bovee JVMG; Department of Pathology, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Dei Tos AP; Department of Pathology, Azienda Ospedale-Università Padova, Padova, Italy., Fletcher C; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Baumhoer D; Department of Pathology, University Hospital Basel, Basel, Switzerland., Sbaraglia M; Department of Pathology, Azienda Ospedale-Università Padova, Padova, Italy., Schaefer IM; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Miceli R; Unit of Biostatistics for Clinical Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Gronchi A; Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Stacchiotti S; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Publikováno v: The American journal of surgical pathology [Am J Surg Pathol] 2024 Oct 28. Date of Electronic Publication: 2024 Oct 28.