Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Demi Both"'
Autor:
Marco V. Haselager, Rachel Thijssen, Danique Bax, Demi Both, Francien De Boer, Simon Mackay, Julie Dubois, Clemens Mellink, Arnon P. Kater, Eric Eldering
Publikováno v:
Molecular Oncology, Vol 17, Iss 6, Pp 1112-1128 (2023)
Preventing or overcoming resistance to the Bcl‐2 inhibitor venetoclax is an emerging unmet clinical need in patients with chronic lymphocytic leukaemia (CLL). The upregulation of anti‐apoptotic Bcl‐2 members through signalling pathways within t
Externí odkaz:
https://doaj.org/article/2e43009de0ac4b10a008f5313a882ab0
Autor:
Francesca Favaro, Demi Both, Ingrid A. M. Derks, Marcel Spaargaren, Cristina Muñoz-Pinedo, Eric Eldering
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-9 (2023)
Abstract Impairments in protein folding in the endoplasmic reticulum (ER) lead to a condition called ER stress, which can trigger apoptosis via the mitochondrial or the death receptor (extrinsic) pathway. There is controversy concerning involvement o
Externí odkaz:
https://doaj.org/article/e736815b837b4dfbba0af30109427fa2
Autor:
Francesca Favaro, Fedra Luciano-Mateo, Joaquim Moreno-Caceres, Miguel Hernández-Madrigal, Demi Both, Chiara Montironi, Franziska Püschel, Ernest Nadal, Eric Eldering, Cristina Muñoz-Pinedo
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-12 (2022)
Abstract Interleukin-8 (IL-8/CXCL8) is a pro-angiogenic and pro-inflammatory chemokine that plays a role in cancer development. Non-small cell lung carcinoma (NSCLC) produces high amounts of IL-8, which is associated with poor prognosis and resistanc
Externí odkaz:
https://doaj.org/article/f53ac57ae28b49ff9a2963780dcda7af
Autor:
null Marco V. Haselager, null Rachel Thijssen, null Danique Bax, null Demi Both, null Francien De Boer, null Simon Mackay, null Julie Dubois, null Clemens Mellink, null Arnon P. Kater, null Eric Eldering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bea98a1602493861cf6f7162912b1e
https://doi.org/10.1002/1878-0261.13364/v3/response1
https://doi.org/10.1002/1878-0261.13364/v3/response1
Autor:
Marco V. Haselager, Rachel Thijssen, Danique Bax, Demi Both, Francien De Boer, Simon Mackay, Julie Dubois, Clemens Mellink, Arnon P. Kater, Eric Eldering
Publikováno v:
Molecular oncology. Elsevier
Haselager, M V, Thijssen, R, Bax, D, Both, D, de Boer, F, Mackay, S, Dubois, J, Mellink, C, Kater, A P & Eldering, E 2022, ' JAK–STAT signalling shapes the NF-κB response in CLL towards venetoclax sensitivity or resistance via Bcl-XL ', Molecular oncology . https://doi.org/10.1002/1878-0261.13364
Haselager, M V, Thijssen, R, Bax, D, Both, D, de Boer, F, Mackay, S, Dubois, J, Mellink, C, Kater, A P & Eldering, E 2022, ' JAK–STAT signalling shapes the NF-κB response in CLL towards venetoclax sensitivity or resistance via Bcl-XL ', Molecular oncology . https://doi.org/10.1002/1878-0261.13364
Preventing or overcoming resistance to the Bcl-2 inhibitor venetoclax is an emerging unmet clinical need in patients with chronic lymphocytic leukaemia (CLL). The upregulation of anti-apoptotic Bcl-2 members through signalling pathways within the tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d35d8654653f5b16a694f07088fe92
https://pure.amc.nl/en/publications/jakstat-signalling-shapes-the-nfb-response-in-cll-towards-venetoclax-sensitivity-or-resistance-via-bclxl(4a996479-0622-45fc-93e2-335ac2000c94).html
https://pure.amc.nl/en/publications/jakstat-signalling-shapes-the-nfb-response-in-cll-towards-venetoclax-sensitivity-or-resistance-via-bclxl(4a996479-0622-45fc-93e2-335ac2000c94).html
Autor:
Sander, de Kivit, Mark, Mensink, Anna T, Hoekstra, Ilana, Berlin, Rico J E, Derks, Demi, Both, Muhammad A, Aslam, Derk, Amsen, Celia R, Berkers, Jannie, Borst
Publikováno v:
Nature metabolism. 2(10)
Following activation, conventional T (T