Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Demetra D, Christou"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Parkinson’s Disease (PD) is a prevalent and complex age-related neurodegenerative condition for which there are no disease-modifying treatments currently available. The pathophysiological process underlying PD remains incompletely understood but in
Externí odkaz:
https://doaj.org/article/12176350909449a69de222d3476df07c
Autor:
Trace Thome, Ravi A. Kumar, Sarah K. Burke, Ram B. Khattri, Zachary R. Salyers, Rachel C. Kelley, Madeline D. Coleman, Demetra D. Christou, Russell T. Hepple, Salvatore T. Scali, Leonardo F. Ferreira, Terence E. Ryan
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
Chronic kidney disease (CKD) causes progressive skeletal myopathy involving atrophy, weakness, and fatigue. Mitochondria have been thought to contribute to skeletal myopathy; however, the molecular mechanisms underlying muscle metabolism changes in C
Externí odkaz:
https://doaj.org/article/6eeb058807be4b4b9dc967c2b9ae67f9
Autor:
Kellie B Cooper, Stephanie Lapierre, Montserrat Carrera Seoane, Katie Lindstrom, Ricarda Pritschmann, Marissa Donahue, Demetra D Christou, Megan A McVay, Danielle E Jake-Schoffman
Publikováno v:
Translational Behavioral Medicine. 13:268-280
Given the broad benefits of physical activity (PA) but low PA levels among breast cancer survivors (i.e., women who have received a breast cancer diagnosis), innovative and evidence-based techniques are needed to motivate and support exercise. This s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::deaa9739bcc7e71f0dc9d236d5a790cf
https://doi.org/10.1093/tbm/ibac111
https://doi.org/10.1093/tbm/ibac111
Autor:
Danielle E Jake-Schoffman, Meredith S Berry, Marissa L Donahue, Demetra D Christou, Jesse Dallery, Jillian M Rung
Publikováno v:
Substance Abuse: Research and Treatment, Vol 14 (2020)
Background: Opioid maintenance treatment (OMT) is the standard for treatment of opioid use disorder, but some individuals on OMT experience disrupted sleep, heightened sensitivity to pain, and continued relapse to non-medical opioid use. An adjunctiv
Externí odkaz:
https://doaj.org/article/bbe941a570bb4ecabdfe8f0c7ac676bd
Autor:
Ryan J. Pettit-Mee, Gavin Power, Francisco J. Cabral-Amador, Francisco I. Ramirez-Perez, Rogerio N. Soares, Neekun Sharma, Ying Liu, Demetra D. Christou, Jill A. Kanaley, Luis A. Martinez-Lemus, Camila Manrique-Acevedo, Jaume Padilla
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Impaired endothelial insulin signaling and consequent blunting of insulin-induced vasodilation is a feature of type 2 diabetes (T2D) that contributes to vascular disease and glycemic dysregulation. However, the molecular mechanisms underlying endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a1579077331c2207c0033666d5a3ad
https://doi.org/10.1152/ajpregu.00006.2022
https://doi.org/10.1152/ajpregu.00006.2022
Autor:
Dongyu Zhang, Kori A. Spiropoulos, Akemi Wijayabahu, Demetra D. Christou, Shama D. Karanth, Stephen D. Anton, Christiaan Leeuwenburgh, Muxuan Liang, Meghann Wheeler, Danting Yang, Aduse-Poku Livingstone, Robert T. Mankowski, Ting-Yuan David Cheng, Hanchao Zhang, Erin M. Siegel, Frank J. Penedo, Jonathan D. Licht, Dejana Braithwaite
Publikováno v:
Nutrition (Burbank, Los Angeles County, Calif.). 107
Individuals with prior cancer diagnosis are more likely to have low muscle mass (LMM) than their cancer-free counterparts. Understanding the effects of LMM on the prognosis of cancer survivors can be clinically important. The aim of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2357f30d3f1048c42e1d59c4e1e1f023
https://pubmed.ncbi.nlm.nih.gov/36563433
https://pubmed.ncbi.nlm.nih.gov/36563433
Autor:
Demetra D. Christou, Jeung-Ki Yoo, Andrew Judge, Michael P. Wiggs, Hazel H. Szeto, David D. Fuller, Oh Sung Kwon, Ashley J. Smuder, Brandon M. Roberts
Publikováno v:
Oncotarget
Cancer cachexia is a syndrome characterized by profound cardiac and diaphragm muscle wasting, which increase the risk of morbidity in cancer patients due to failure of the cardiorespiratory system. In this regard, muscle relies greatly on mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f62d5d318f8954827edb4e909abb6d
https://doi.org/10.18632/oncotarget.27748
https://doi.org/10.18632/oncotarget.27748
Autor:
Samuel Vargas Munhoz, Alvaro Reischak-Oliveira, Jerri Luiz Ribeiro, Demetra D. Christou, Juliano Boufleur Farinha, Thiago Rozales Ramis, Francesco Pinto Boeno, Cesar Eduardo Jacintho Moritz, Rodrigo Leal-Menezes
Publikováno v:
Journal of Hypertension. 38:2501-2509
OBJECTIVE The current randomized controlled trial tested the hypothesis that both aerobic training and dynamic resistance training will improve inflammation, endothelial function and 24-h ambulatory blood pressure (ABP) in middle-aged adults with hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd36e2c2b2b44ad980bd5e2b5b2dfa48
https://doi.org/10.1097/hjh.0000000000002581
https://doi.org/10.1097/hjh.0000000000002581
Autor:
Rachel C. Kelley, Stephanie S. Lapierre, Derek R. Muscato, Dongwoo Hahn, Demetra D. Christou, Leonardo F. Ferreira
Publikováno v:
Experimental physiology. 107(11)
What is the central question of this study? This study addresses whether a high-fat, high-sucrose diet causes cardiac and diaphragm muscle abnormalities in male rats and whether supplementation with the antioxidant N-acetylcysteine reverses diet-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66347c98a5a524477ef3e618abf82e04
https://pubmed.ncbi.nlm.nih.gov/35938289
https://pubmed.ncbi.nlm.nih.gov/35938289
Autor:
Aaron B. Morton, Noriko Ichinoseki-Sekine, Andres Mor Huertas, J. Matthew Hinkley, Demetra D. Christou, Ashley J. Smuder
Publikováno v:
Mitochondrion. 45:52-62
Doxorubicin (DOX) is a highly effective anthracycline antibiotic. Unfortunately, the clinical use of DOX is limited by the risk of deleterious effects to cardiac and respiratory (i.e. diaphragm) muscle, resulting from mitochondrial reactive oxygen sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88e709b5c398d2cef822a195ea96a48
https://doi.org/10.1016/j.mito.2018.02.005
https://doi.org/10.1016/j.mito.2018.02.005