Hair hormone data from Syrian refugee children: Perspectives from a two-year longitudinal study

Autor: Andrew K. May, Demelza Smeeth, Fiona McEwen, Patricia Moghames, Elie Karam, Michael J. Rieder, Abdelbaset A. Elzagallaai, Stan van Uum, Michael Pluess

Publikováno v: Comprehensive Psychoneuroendocrinology, Vol 18, Iss , Pp 100231- (2024)

For numerous issues of convenience and acceptability, hair hormone data have been increasingly incorporated in the field of war trauma and forced displacement, allowing retrospective examination of several biological metrics thought to covary with re

Externí odkaz: https://doaj.org/article/6626e4892eee44e39148575be70afb18

Cohort profile: biological pathways of risk and resilience in Syrian refugee children (BIOPATH)

Autor: Fiona S. McEwen, Cassandra Popham, Patricia Moghames, Demelza Smeeth, Bernadette de Villiers, Dahlia Saab, Georges Karam, John Fayyad, Elie Karam, Michael Pluess

Publikováno v: Social Psychiatry and Psychiatric Epidemiology. 57:873-883

The BIOPATH cohort was established to explore the interplay of psychosocial and biological factors in the development of resilience and mental health problems in Syrian refugee children. Based in Lebanon, a middle-income country significantly impacte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681c3133418456afdc822fbe5eeb9b59
https://doi.org/10.1007/s00127-022-02228-8

Prolactin, Estradiol and Testosterone Differentially Impact Human Hippocampal Neurogenesis in an In Vitro Model

Autor: Rodrigo R.R. Duarte, Sandrine Thuret, Timothy R. Powell, Demelza Smeeth, Ioanna Kourouzidou

Publikováno v: Neuroscience

Highlights • Human hippocampal progenitor cells (HPCs) and tissue express classical sex hormone receptors. • Prolactin does not impact human HPCs maintained in a proliferative state. • Prolactin increases neuronal differentiation of human HPCs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79be9ca5ba6757d62536be1fef095375
http://europepmc.org/articles/PMC7839971

Telomere length and human hippocampal neurogenesis

Autor: Alish B. Palmos, Douglas F. Nixon, Demelza Smeeth, Rodrigo R.R. Duarte, Timothy R. Powell, Sandrine Thuret, Erin C. Hedges

Publikováno v: Palmos, A B, Duarte, R R R, Smeeth, D M, Hedges, E C, Nixon, D F, Thuret, S & Powell, T R 2020, ' Telomere length and human hippocampal neurogenesis ', Neuropsychopharmacology . https://doi.org/10.1038/s41386-020-00863-w
Neuropsychopharmacology

Short telomere length is a risk factor for age-related disease, but it is also associated with reduced hippocampal volumes, age-related cognitive decline and psychiatric disorder risk. The current study explored whether telomere shortening might have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5740cb27d3ecacab3c2bdd771a168c1
https://doi.org/10.1038/s41386-020-00863-w

Inter-individual variation in genes governing human hippocampal progenitor differentiation in vitro is associated with hippocampal volume in adulthood

Autor: Timothy R, Powell, Tytus, Murphy, Sang H, Lee, Rodrigo R R, Duarte, Hyun Ah, Lee, Demelza, Smeeth, Jack, Price, Gerome, Breen, Sandrine, Thuret

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Powell, T R, Murphy, T, Lee, S H, Duarte, R R R, Lee, H A, Smeeth, D, Price, J, Breen, G & Thuret, S 2017, ' Inter-individual variation in genes governing human hippocampal progenitor differentiation in vitro is associated with hippocampal volume in adulthood ', Scientific Reports, vol. 7, no. 1, 15112, pp. 1-10 . https://doi.org/10.1038/s41598-017-15042-z, https://doi.org/10.1038/s41598-017-15042-z
Scientific Reports

Hippocampal volumes are smaller in psychiatric disorder patients and lower levels of hippocampal neurogenesis are the hypothesized cause. Understanding which molecular processes regulate hippocampal progenitor differentiation might aid in the identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::34393806890b3494e1a1e57443656786
http://link.springer.com/article/10.1038/s41598-017-15042-z