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pro vyhledávání: '"Demartino Jason L"'
SCH 43478 and analogs: in vitro activity and in vivo efficacy of novel agents for herpesvirus type 2
Autor:
Ann D. Kwong, Eric Ferrari, Randi Albin, Gilbert Jirau-Lucca, Christine Risano, Edward J Rozthon, Angela Skelton, Jacquelyn Wright-Minogue, Demartino Jason L, Melvin Lieberman, Robert Chase, Stuart Cox, Adrian Afonso, Joseph M. Kelly, Peter Buontempo, John O'Connell
Publikováno v:
Antiviral Research. 35:139-146
SCH 43478 and analogs are a class of non-nucleoside antiviral agents that have potent and selective activity against herpes simplex virus type 2 (HSV-2). The IC50 for these compounds in plaque reduction analysis using Vero cells ranges from 0.8 to 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bae380c45e196ba43c78fed69edf04
https://doi.org/10.1016/s0166-3542(97)00023-5
https://doi.org/10.1016/s0166-3542(97)00023-5
Autor:
Jerome Schwartz, Demartino Jason L, Chin-Chung Linn, V. Girijavallabhan, Peter Buontempo, John O'Connell, Eric Ferrari, Stuart Cox, Jacquelyn Wright-Minogue, Rozhon Edward J, Angela Skelton
Publikováno v:
Antiviral Research. 32:71-79
SCH 47802 and its derivatives are potent inhibitors of enteroviruses in vitro. The IC50 for SCH 47802 ranges from 0.03 to 10 micrograms/ml when tested against a spectrum of enteroviruses in plaque reduction assays. The compounds have in vitro therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de40810d7e95fed621d05d1c1a3d01c8
https://doi.org/10.1016/0166-3542(95)00979-5
https://doi.org/10.1016/0166-3542(95)00979-5
Autor:
Karen N Lentz, John O'Connell, Jerome Schwartz, Angela Skelton, Stuart Cox, Peter Buontempo, Sheila C. Geisler, V. Girijavallabhan, A. D. Smith, E. Rozhon, Demartino Jason L, Edward Arnold
Publikováno v:
Structure (London, England : 1993). 5(7)
Background: Polioviruses are human pathogens and the causative agents of poliomyelitis. Polioviruses are icosahedral single-standed RNA viruses, which belong to the picornavirus family, and occur as three distinct serotypes. All three serotypes of po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a125a3d185fee08e8e7ac7122d0bf685
https://pubmed.ncbi.nlm.nih.gov/9261087
https://pubmed.ncbi.nlm.nih.gov/9261087
Autor:
Randi Albin, John F. Modlin, Eric Ferrari, V. Girijavallabhan, Demartino Jason L, Jacquelyn Wright-Minogue, Peter Buontempo, E. Rozhon, Angela Skelton, John O'Connell, Stuart Cox
Publikováno v:
Antimicrobial agents and chemotherapy. 41(6)
SCH 48973 is a novel molecule with potent, selective, antienterovirus activity. In assays of the cytopathic effect against five picornaviruses, SCH 48973 had antiviral activity (50% inhibitory concentrations [IC50s]) of 0.02 to 0.11 microg/ml, with n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55b788f6907497cb5984bb126c8d145
https://pubmed.ncbi.nlm.nih.gov/9174174
https://pubmed.ncbi.nlm.nih.gov/9174174
Autor:
Cox, Stuart, Buontempo, Peter J., Wright-Minogue, Jacquelyn, DeMartino, Jason L., Skelton, Angela M., Ferrari, Eric, Schwartz, Jerome, Rozhon, Edward J., Linn, Chin-Chung, Girijavallabhan, V., O'Connell, John F.
Publikováno v:
In Antiviral Research 1996 32(2):71-79