Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Demao Zhang"'
Autor:
Fei Fang, Jie Yang, Jiahe Wang, Tiantian Li, Erxiang Wang, Demao Zhang, Xiaoheng Liu, Chenchen Zhou
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Osteoporosis is a widely observed condition characterized by the systemic deterioration of bone mass and microarchitecture, which increases patient susceptibility to fragile fractures. The intricate mechanisms governing bone homeostasis are
Externí odkaz:
https://doaj.org/article/7eb62cb688d045ce8cd9ebb16c40563f
Autor:
Guanyue Su, Demao Zhang, Tiantian Li, Tong Pei, Jie Yang, Shasha Tu, Sijun Liu, Jie Ren, Yaojia Zhang, Mengmeng Duan, Xinrui Yang, Yang Shen, Chenchen Zhou, Jing Xie, Xiaoheng Liu
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Matrix vesicles (MVs) have shown strong effects in diseases such as vascular ectopic calcification and pathological calcified osteoarthritis and in wound repair of the skeletal system due to their membranous vesicle characteristics and abund
Externí odkaz:
https://doaj.org/article/5af0d59e7bea40b8bcc8ad0a20c670e9
Publikováno v:
Bone & Joint Research, Vol 12, Iss 7, Pp 397-411 (2023)
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by progressive cartilage degradation, synovial membrane inflammation, osteophyte formation, and subchondral bone sclerosis. Pathological changes in cartilage and subchondral bo
Externí odkaz:
https://doaj.org/article/30de049327294d7bbd3f5b1ba1a32304
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Fibroblast growth factor 19 (FGF19) has appeared as a new possible avenue in the treatment of skeletal metabolic disorders. However, the role of FGF19 on cell cycle progression in skeletal system is poorly understood. Here we demonstrated th
Externí odkaz:
https://doaj.org/article/0d64514feeda4efd820743b6fbc7dcfc
Autor:
Chenchen Zhou, Chunli Wang, Kang Xu, Zhixing Niu, Shujuan Zou, Demao Zhang, Zhiyong Qian, Jinfeng Liao, Jing Xie
Publikováno v:
Bioactive Materials, Vol 25, Iss , Pp 615-628 (2023)
Cartilage injury affects numerous individuals, but the efficient repair of damaged cartilage is still a problem in clinic. Hydrogel is a potent scaffold candidate for tissue regeneration, but it remains a big challenge to improve its mechanical prope
Externí odkaz:
https://doaj.org/article/a30c21321b044ffd9bdbe7ff46357bc3
Autor:
Shiyi Kan, Caixia Pi, Li Zhang, Daimo Guo, Zhixing Niu, Yang Liu, Mengmeng Duan, Xiahua Pu, Mingru Bai, Chenchen Zhou, Demao Zhang, Jing Xie
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Fibroblast growth factor 19 (FGF19) is recognized to play an essential role in cartilage development and physiology, and has emerged as a potential therapeutic target for skeletal metabolic diseases. However, FGF19-mediated cellular behavior
Externí odkaz:
https://doaj.org/article/586c013bcbad4eaca10fdd903c4e108a
Autor:
Zuping Wu, Yuying He, Sirui Chen, Li Zhu, Jiahe Wang, Demao Zhang, Jing Xie, Shujuan Zou, Chenchen Zhou
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Background Orthodontic tooth movement inevitably induces cementum resorption, which is an urgent problem for orthodontists to confront. Human periodontal ligament stem cells (hPDLSCs) exert an important role in the orthodontic tooth movement
Externí odkaz:
https://doaj.org/article/835b7542dc6b473d99d7ede8d8d14ef3
Publikováno v:
Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101462- (2023)
Gap junctions, which are mainly composed of connexin units, play an indispensable role in cell morphogenesis, proliferation, migration, adhesion and differentiation of osteoblast lineage cells, and thus mediate bone development, homeostasis and disea
Externí odkaz:
https://doaj.org/article/f2bec5f2ef484ff59ae407c97f7759a1
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Mineralized tissues, such as teeth and bones, pose significant challenges for repair due to their hardness, low permeability, and limited blood flow compared to soft tissues. Bone morphogenetic proteins (BMPs) have been identified as playing a crucia
Externí odkaz:
https://doaj.org/article/7454d97dea174c43973fd86953e5f219
Autor:
Mengmeng Duan, Shuang Xia, Yang Liu, Xiaohua Pu, Yukun Chen, Yilin Zhou, Minglei Huang, Caixia Pi, Demao Zhang, Jing Xie
Publikováno v:
Materials Today Bio, Vol 20, Iss , Pp 100682- (2023)
Articular cartilage, composed of collagen type II as a major extracellular matrix and chondrocyte as a unique cell type, is a specialized connective tissue without blood vessels, lymphatic vessels and nerves. This distinctive characteristic of articu
Externí odkaz:
https://doaj.org/article/de01fb8db0c448d7ba259f182a22a5e3