Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Delyth J. Goodwin"'
Autor:
Delyth J. Goodwin, Adrian Whitehouse, Mathew S. Giles, Kersten T. Hall, Michael A. Calderwood, David A. Matthews
Publikováno v:
Journal of Virology. 76:11612-11622
The role of the gamma-2 herpesvirus open reading frame (ORF) 73 gene product has become the focus of considerable interest. It has recently been shown that the Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA) i
Autor:
Delyth J. Goodwin, Mathias Thurau, Peter G. Smith, Adrian Whitehouse, Helmut Fickenscher, Matthew S. Walters
Publikováno v:
Journal of Virology. 75:4008-4013
Herpesviruses occur in two distinct forms of infection, lytic replication and latent persistence. In this study, we investigated the molecular mechanisms that govern the latent-lytic switch in the prototype gamma-2 herpesvirus, herpesvirus saimiri (H
Autor:
Mathew S. Giles, Delyth J. Goodwin, Kersten T. Hall, Michael A. Calderwood, Alexander F. Markham, Adrian Whitehouse
Publikováno v:
Journal of General Virology. 81:2653-2658
The herpesvirus saimiri (HVS) gene product encoded by ORF73 shares a limited homology with the ORF73 encoded protein of Kaposi’s sarcomaassociated herpesvirus (KSHV). It has recently been shown that the KSHV ORF73 protein is expressed during a late
Autor:
Mathew S. Giles, Adrian Whitehouse, Alex J. Stevenson, Kersten T. Hall, Delyth J. Goodwin, Alex F. Markham, Michael A. Calderwood
Publikováno v:
British Journal of Cancer
The potential use of oncolytic viruses in the treatment of cancer has been investigated for some time. A variety of agents have been studied, including some which appear to be selectively replication-competent in cancer cell lines. In this study, we
Autor:
Alex J. Stevenson, Adrian Whitehouse, Paul C. Gibson, Delyth J. Goodwin, Kersten T. Hall, Alex F. Markham
Publikováno v:
Journal of Virology. 73:9756-9763
The herpesvirus saimiri open reading frame (ORF) 50 produces two transcripts. The first is spliced, contains a single intron, and is detected at early times during the productive cycle, whereas the second is expressed later and is produced from a pro
Autor:
Kersten T. Hall, David Meredith, Delyth J. Goodwin, Adrian Whitehouse, Alexander F. Markham, Matthew Cooper, Alex J. Stevenson
Publikováno v:
Europe PubMed Central
The herpesvirus saimiri (HVS) gene product encoded by ORF 57 shares limited C-terminal similarity with herpes simplex virus 1 ICP27, a protein that has been demonstrated to be involved in the inhibition of host-cell splicing and is responsible for th
Autor:
Delyth J. Goodwin, Stuart A. Wilson, Adrian Whitehouse, Ben J. L. Williams, James R. Boyne, Guillaume M. Hautbergue, Louise Roaden
HVS (herpesvirus saimiri) is the prototype γ-2 herpesvirus. This is a subfamily of herpesviruses gaining importance since the identification of the first human γ-2 herpesvirus, Kaposi's sarcoma-associated herpesvirus. The HVS ORF 57 (open reading f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814edff6c3c22b72750089ab2dac089b
https://europepmc.org/articles/PMC1134957/
https://europepmc.org/articles/PMC1134957/
Autor:
Michael A. Calderwood, Kersten T. Hall, Delyth J. Goodwin, Adrian Whitehouse, Alex F. Markham, Mathew S. Giles
Publikováno v:
The Journal of general virology. 81(Pt 9)
Herpesvirus saimiri (HVS) ORF 57 is homologous to genes identified in all classes of herpesviruses. We have previously shown that ORF 57 encodes a multifunctional protein, responsible for both transactivation and repression of viral gene expression a
Autor:
Alex F. Markham, Michael A. Calderwood, Delyth J. Goodwin, Mathew S. Giles, Kersten T. Hall, Alex J. Stevenson, Ian M. Carr, Adrian Whitehouse
Herpesvirus saimiri (HVS) is the prototype gamma-2 herpesvirus, or rhadinovirus; it has significant homology to the human gammaherpesviruses Kaposi's sarcoma-associated virus (KSHV) and Epstein-Barr virus (EBV) and the murine gammaherpesvirus murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf722a360b19b707af944432fecb22d
https://europepmc.org/articles/PMC112253/
https://europepmc.org/articles/PMC112253/
Publikováno v:
Europe PubMed Central
The herpesvirus saimiri open reading frame (ORF) 57 is homologous to genes identified in all classes of herpesviruses. It has previously been shown to regulate gene expression through a posttranscriptional mechanism. We demonstrate in this report tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6ff18e12c2292d2a5ede74caed8db1
http://europepmc.org/abstract/med/10559371
http://europepmc.org/abstract/med/10559371