Design, synthesis, and biological activity of D-bishomo-1α,25-dihydroxyvitamin D 3 analogs and their crystal structures with the vitamin D nuclear receptor.

Autor: Fabisiak A; Department of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland. Electronic address: afabisiak@chem.uw.edu.pl., Brzeminski P; Department of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland., Sicinski RR; Department of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland., Rochel N; Department of Integrative Structural Biology, IGBMC - Université de Strasbourg, CNRS UMR 7104, INSERM U1258, 67400, Illkirch, France., Maj E; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Rudolf Weigl Street, 53-114, Wrocław, Poland., Filip-Psurska B; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Rudolf Weigl Street, 53-114, Wrocław, Poland., Wietrzyk J; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Rudolf Weigl Street, 53-114, Wrocław, Poland., Plum LA; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI, 53706, USA., DeLuca HF; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI, 53706, USA.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 May 05; Vol. 271, pp. 116403. Date of Electronic Publication: 2024 Apr 10.

Antibody production in mice requires neither vitamin D, nor the vitamin D receptor.

Autor: Plum LA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, United States., Blaser W; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, United States., Peter L; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, United States., Prahl J; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, United States., Seeman J; Organic Lab, DiaSorin Inc., Stillwater, MN, United States., DeLuca HF; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Oct 20; Vol. 13, pp. 960405. Date of Electronic Publication: 2022 Oct 20 (Print Publication: 2022).

Vitamin D esters are the major form of vitamin D produced by UV irradiation in mice.

Autor: Duchow EG; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, 271a Biochemistry, Madison, WI, 53706, USA., Sibilska-Kaminski IK; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, 271a Biochemistry, Madison, WI, 53706, USA., Plum LA; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, 271a Biochemistry, Madison, WI, 53706, USA., DeLuca HF; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, 271a Biochemistry, Madison, WI, 53706, USA. deluca@biochem.wisc.edu.

Publikováno v: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology [Photochem Photobiol Sci] 2022 Aug; Vol. 21 (8), pp. 1399-1404. Date of Electronic Publication: 2022 Apr 30.

Novel superagonist analogs of 2-methylene calcitriol: Design, molecular docking, synthesis and biological evaluation.

Autor: Sibilska-Kaminski IK; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA., Fabisiak A; Department of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland., Brzeminski P; Department of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland., Plum LA; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA., Sicinski RR; Department of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland., DeLuca HF; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA. Electronic address: deluca@biochem.wisc.edu.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2022 Jan; Vol. 118, pp. 105416. Date of Electronic Publication: 2021 Oct 11.

Vitamin D receptor and its antiproliferative effect in human pulmonary arterial hypertension.

Autor: Callejo, Maria^1,2 (AUTHOR), Morales-Cano, Daniel^1,2,3 (AUTHOR), Olivencia, Miguel A.^1,2,3 (AUTHOR), Mondejar-Parreño, Gema⁴ (AUTHOR), Barreira, Bianca^1,2,3 (AUTHOR), Tura-Ceide, Olga^2,5,6 (AUTHOR), Martínez, Victor G.^7,8,9 (AUTHOR), Serrano-Navarro, Alvaro¹⁰ (AUTHOR), Moreno, Laura^1,2,3 (AUTHOR), Morrell, Nick¹¹ (AUTHOR), Perros, Frédéric¹² (AUTHOR), Vicente, Angeles¹³ (AUTHOR), Cogolludo, Angel^1,2,3 (AUTHOR), Perez-Vizcaino, Francisco^1,2,3 (AUTHOR) fperez@med.ucm.es

Publikováno v: Scientific Reports. 11/10/2024, Vol. 14 Issue 1, p1-14. 14p.