Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Deltorphin I"'
Autor:
Oliwia Frączak, Michał Nowakowski, Aleksandra Olma, Anika Lasota, Maciej Maciejczyk, Andrzej Ejchart, Adriana Muchowska
Publikováno v:
Chemical Biology & Drug Design. 87:824-832
This article describes new deltorphin I analogs in which phenylalanine residues were replaced by the corresponding (R) or (S)-α-benzyl-β-azidoalanine, α-benzyl-β-(1-pyrrolidinyl)alanine, α-benzyl-β-(1-piperidinyl)alanine, and α-benzyl-β-(4-mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5939294c45bd1f0b905670f0b89bcab3
https://doi.org/10.1111/cbdd.12730
https://doi.org/10.1111/cbdd.12730
Autor:
Aleksandra Olma, Anika Lasota, Andrzej Ejchart, Oliwia Frączak, Michał Nowakowski, Andrzej W. Lipkowski, Anna Leśniak, Adriana Muchowska
Publikováno v:
Journal of Peptide Science. 21:120-125
New analogues of deltorphin I (DT I, Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2 ), with the D-Ala residue in position 2 replaced by α-methyl-β-azido(amino, 1-pyrrolidinyl, 1-piperidinyl or 4-morpholinyl)alanine, were synthesized by a combination of solid-ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d21e2d9b9b706164233f0ba58b4ba94
https://doi.org/10.1002/psc.2738
https://doi.org/10.1002/psc.2738
Autor:
George L. Wilcox, Robert O. Messing, Carolyn A. Fairbanks, M. D. Metcalf, Daniel J. Schuster, Kelley F. Kitto
Publikováno v:
British Journal of Pharmacology. 172:642-653
Background and Purpose We recently found that PKCe was required for spinal analgesic synergy between two GPCRs, δ opioid receptors and α2A adrenoceptors, co-located in the same cellular subpopulation. We sought to determine if co-delivery of μ and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b0834252d2e7850f59c4c334df3f136
https://doi.org/10.1111/bph.12774
https://doi.org/10.1111/bph.12774
Autor:
Benjamin Aguila, Géza Tóth, Laurent Coulbault, Florian Le Bras, Stéphane Allouche, Philippe Jauzac, Ahmed Hasbi, Audrey Davis, Anna Borsodi, Nicolas Marie, Vsevolod V. Gurevich
Publikováno v:
Cellular Signalling. 24:699-707
We have previously reported on the differential regulation of the human δ-opioid receptor (hDOR) by alkaloid (etorphine) and peptidic (DPDPE and deltorphin I) ligands, in terms of both receptor desensitization and post-endocytic sorting. Since sarre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8654fd7512f93c818ce9315b96ec7add
https://doi.org/10.1016/j.cellsig.2011.10.018
https://doi.org/10.1016/j.cellsig.2011.10.018
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Journal of Peptide Science. 15:777-782
beta-Amino acids containing hybrid peptides and beta-peptides show great potential as peptidomimetics. In this paper we describe the synthesis and affinity toward the micro- and delta-opioid receptors of beta-peptides, analogues of Leu-enkephalin, de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a027014bb704ecd8e8db700aa9b5e494
https://doi.org/10.1002/psc.1175
https://doi.org/10.1002/psc.1175
Autor:
Grzegorz Bujacz, Marek J. Potrzebowski, Danuta Pentak, Jarosław Gajda, Włodzimierz Ciesielski, Katarzyna Trzeciak-Karlikowska, Agata Jeziorna, Anna Bujacz
Publikováno v:
Crystal Growth & Design. 9:4051-4059
Tyr-d-Ala-Phe is a “message sequence” of naturally occurring opioid peptides, deltorphin I (Tyr-d-Ala-Phe-Asp-Val-Val-Gly-NH2), deltorphin II (Tyr-d-Ala-Phe-Glu-Val-Val-Gly-NH2), and dermorphin (Tyr-d-Ala-Phe-Gly-Tyr-Pro-Ser-NH2). Analogous hepta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::938e0e4c5424331598e7fa854a4c927c
https://doi.org/10.1021/cg900264x
https://doi.org/10.1021/cg900264x
Autor:
Pier Carlo Montecucchi, Luigia Gozzini, Vittorio Erspamer, Silvano Piani, Roberto De Castiglione
Publikováno v:
International Journal of Peptide and Protein Research. 17:275-283
Dermorphin, a heptapeptide with very potent opiate-like activity, has been isolated from methanol extracts of the skin of the South American frog Phyllomedusa sauvagei. The amino acid sequence of the peptide is: H-Try-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2270b3b49955366cf42f142b6653fc
https://doi.org/10.1111/j.1399-3011.1981.tb01993.x
https://doi.org/10.1111/j.1399-3011.1981.tb01993.x
Publikováno v:
International Journal of Peptide and Protein Research. 46:47-55
A series of dermorphin analogues containing an N-alkylated amino-acid residue Xaa in the 2-position of the peptide sequence was synthesized (Xaa =N-methylalanine, proline, pipecolic acid, N-methylphenylalanine, 1,2,3,4-tetrahydroisoquinoline-3-carbox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf1a3d5d1e5b0dff3714be55de5a37e
https://doi.org/10.1111/j.1399-3011.1995.tb00580.x
https://doi.org/10.1111/j.1399-3011.1995.tb00580.x
Publikováno v:
International Journal of Peptide and Protein Research. 48:411-419
The beta-casomorphin-5 analog H-Tyr-c[-D-Orn-2-Nal-D-Pro-Gly-] (2-Nal = 2-naphthylalanine) was the first reported cyclic opioid peptide with mixed mu agonist/delta antagonist properties [R. Schmidt et al. (1994) J. Med. Chem. 37, 1136-1144]. The 2-Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::978f936bfc0d2728acb2b6562223ad4b
https://doi.org/10.1111/j.1399-3011.1996.tb00859.x
https://doi.org/10.1111/j.1399-3011.1996.tb00859.x