Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Delta–notch"'
Autor:
Naoto Sambe, Masaharu Yoshihara, Teppei Nishino, Ryosuke Sugiura, Takahiro Nakayama, Chandra Louis, Satoru Takahashi
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Objective A mammalian Delta-Notch signaling component, Notch1, has been suggested for its expression during the normal sperm development although its conditional deletion caused no apparent abnormalities. Since we established our original tr
Externí odkaz:
https://doaj.org/article/770f38d900274e69a599aaf7efe5b9b5
Autor:
Ryosuke Sugiura, Takahiro Nakayama, Teppei Nishino, Naoto Sambe, Freddy Radtke, Masaharu Yoshihara, Satoru Takahashi
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Objective A Delta-Notch signaling component, Notch1, is involved in the normal development and multiple disorders of the kidney. Although the increase in Notch1 signaling is crucial to these pathogeneses, the basal signaling level in ‘heal
Externí odkaz:
https://doaj.org/article/7c1bf0cc20784688bc9b986e9d750616
Autor:
Teppei Nishino, Masaharu Yoshihara, Takahiro Nakayama, Takaho Tsuchiya, Saeko Tahara, Haruka Ozaki, Satoru Takahashi
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Objective Portal mesenchymal cells induce the epithelial differentiation of the bile ducts in the developing liver via one of the Delta-Notch signaling components, JAGGED1. Although this differential induction is crucial for normal liver phy
Externí odkaz:
https://doaj.org/article/a3d14774f77c43169b192c0b08c2ba12
Akademický článek
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Publikováno v:
Advances in Difference Equations, Vol 2020, Iss 1, Pp 1-19 (2020)
Abstract In this paper, an improved fractional-order model of boundary formation in the Drosophila large intestine dependent on Delta-Notch pathway is proposed for the first time. The uniqueness, nonnegativity, and boundedness of solutions are studie
Externí odkaz:
https://doaj.org/article/ff1cd70f6f40434b8db05ed7fc8f5588
Publikováno v:
eLife, Vol 10 (2021)
Integrity of rhythmic spatial gene expression patterns in the vertebrate segmentation clock requires local synchronization between neighboring cells by Delta-Notch signaling and its inhibition causes defective segment boundaries. Whether deformation
Externí odkaz:
https://doaj.org/article/92367da8be3e403692bc168062e63d8e
Autor:
Branden R Nelson, Rebecca D Hodge, Ray AM Daza, Prem Prakash Tripathi, Sebastian J Arnold, Kathleen J Millen, Robert F Hevner
Publikováno v:
eLife, Vol 9 (2020)
The hippocampal dentate gyrus (DG) is a unique brain region maintaining neural stem cells (NCSs) and neurogenesis into adulthood. We used multiphoton imaging to visualize genetically defined progenitor subpopulations in live slices across key stages
Externí odkaz:
https://doaj.org/article/f6a9cc73f49c42e5945cb98f7ba78864
Akademický článek
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Akademický článek
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Publikováno v:
Molecular Systems Biology, Vol 13, Iss 1, Pp 1-15 (2017)
Abstract Tissue stem cells produce a constant flux of differentiated cells with distinct proportions. Here, we show that stem cells in colonic crypts differentiate early to form precisely 1:3 ratio of secretory to absorptive cells. This precision is
Externí odkaz:
https://doaj.org/article/a1f0791550cc4955a50f9c9ebe2c5e5f