Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Delphine Valognes"'
Publikováno v:
Journal of Heterocyclic Chemistry. 36:1409-1419
Publikováno v:
Tetrahedron Letters. 40:3693-3696
We describe a protocol for the multigram preparation of a tripeptide found in peptin antibiotics. The N -terminus is an azido group, while the C -terminus is an allyl ester. The molecule may be cleanly and selectively deblocked under neutral conditio
Publikováno v:
Synthetic Communications. 28:1189-1195
A general method for direct preparation of carbamoyl chlorides from corresponding benzylamines using triphosgene is described.
Publikováno v:
Tetrahedron Letters. 42:1907-1909
The synthesis of luzopeptin C has been accomplished by self-assembly of the macrocycle via activation of a pentapeptide monomer. The present work underscores the generality of the spontaneous macrocyclization approach to the peptins, a strategy intro
Publikováno v:
ChemInform. 29
A general method for direct preparation of carbamoyl chlorides from corresponding benzylamines using triphosgene is described.
Publikováno v:
ChemInform. 31
Publikováno v:
ChemInform. 32
Publikováno v:
Angewandte Chemie. 112:2612-2614
Publikováno v:
Angewandte Chemie International Edition. 39:2493-2495
Autor:
Corinne Gillieron, Christian Chabert, Thomas Rückle, Jasna Klicic, Denise Gretener, Jeffrey P. Shaw, Karen Roulin, Didier Leroy, Fabienne Burgat-Charvillon, Dennis D. Church, Susanna Carboni, Matthias Schwarz, Delphine Valognes, Pierre Alain Vitte, Anthony Nichols, Bernard Françon, Vincent Pomel, Dominique Perrin, David Covini, Montserrat Camps, Christian Rommel
Publikováno v:
Journal of medicinal chemistry. 49(13)
Class I phosphoinositide 3-kinases (PI3Ks), in particular PI3Kgamma, have become attractive drug targets for inflammatory and autoimmune diseases. Here, we disclose a novel series of furan-2-ylmethylene thiazolidinediones as selective, ATP-competitiv