Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Delphine T. Marie-Egyptienne"'
Autor:
Graeme A.M. Nimmo, J. Arturo Londoño-Vallejo, Delphine T. Marie-Egyptienne, Marie Eve Brault, Chantal Autexier
Publikováno v:
Cancer Letters. 275:266-276
Cellular viability requires telomere maintenance, which, in mammals, is mainly mediated by the reverse transcriptase telomerase. Telomerase core components are a catalytic subunit TERT and an RNA subunit TR (hTR in humans, mTR in mouse) that carries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902f5c4ba6203a8201752d9feed5af4e
https://doi.org/10.1016/j.canlet.2008.10.027
https://doi.org/10.1016/j.canlet.2008.10.027
Publikováno v:
RNA. 11:1448-1460
Telomerase accurately synthesizes telomeric DNA by reverse transcription of a tightly defined template region in the telomerase RNA (TR). Reverse transcription past the 5′ boundary of the template can cause the incorporation of noncognate nucleotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd43f50ca3a77cb79a4e27ddf7d232c8
https://doi.org/10.1261/rna.2910105
https://doi.org/10.1261/rna.2910105
Publikováno v:
Molecular and Cellular Biology. 24:3720-3733
Human telomerase is a multimer containing two human telomerase RNAs (hTRs) and most likely two human telomerase reverse transcriptases (hTERTs). Telomerase synthesizes multiple telomeric repeats using a unique repeat addition form of processivity. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829b377f5c34aa4e99e6063bd639840c
https://doi.org/10.1128/mcb.24.9.3720-3733.2004
https://doi.org/10.1128/mcb.24.9.3720-3733.2004
Autor:
Qing, Chang, Olga I, Ornatsky, Cameron J, Koch, Naz, Chaudary, Delphine T, Marie-Egyptienne, Richard P, Hill, Scott D, Tanner, David W, Hedley
Publikováno v:
International journal of cancer. 136(5)
Although of fundamental importance to the treatment of cancer patients, the quantitative study of drug distribution and action in vivo at the single cell level is challenging. We used the recently-developed technique of mass cytometry to measure cisp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c901149f8aaac2c946a5f49356e5d89
https://pubmed.ncbi.nlm.nih.gov/25042623
https://pubmed.ncbi.nlm.nih.gov/25042623
Autor:
Johans Fakhoury, Laëtitia Trapp-Fragnet, Chantal Autexier, Denis Rasschaert, Delphine T. Marie-Egyptienne
Publikováno v:
Cellular and Molecular Biology Letters
Cellular and Molecular Biology Letters, Springer Verlag (Germany), 2012, 17 (4), pp.598-615. ⟨10.2478/s11658-012-0031-6⟩
Cellular & Molecular Biology Letters
Cellular and Molecular Biology Letters, Springer Verlag (Germany), 2012, 17 (4), pp.598-615. ⟨10.2478/s11658-012-0031-6⟩
Cellular & Molecular Biology Letters
The minimal vertebrate telomerase enzyme is composed of a protein component (telomerase reverse transcriptase, TERT) and an RNA component (telomerase RNA, TR). Expression of these two subunits is sufficient to reconstitute telomerase activity in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f0565a9a7815c5806c262f26349b5c
https://doi.org/10.2478/s11658-012-0031-6
https://doi.org/10.2478/s11658-012-0031-6
Publikováno v:
Experimental cell research. 314(3)
The indefinite growth of cancer cells requires telomere maintenance, which, in the majority of mammalian cancers is mediated via the enzyme telomerase. The core components of telomerase are a catalytic reverse transcriptase (hTERT in human, mTERT in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305763f928e0d82facd584b3b5835448
https://pubmed.ncbi.nlm.nih.gov/18067891
https://pubmed.ncbi.nlm.nih.gov/18067891
Autor:
Delphine T. Marie-Egyptienne, Maria Antonietta Cerone, J. Arturo Londoño-Vallejo, Chantal Autexier
Publikováno v:
Nucleic Acids Research
The phylogenetically-derived secondary structures of telomerase RNAs (TR) from ciliates, yeasts and vertebrates are surprisingly conserved and contain a pseudoknot domain at a similar location downstream of the template. As the pseudoknot domains of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802554e31069c9a17770352b6e605916
https://pubmed.ncbi.nlm.nih.gov/16192571
https://pubmed.ncbi.nlm.nih.gov/16192571