Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Delphine Roussel"'
Autor:
Maria-Belen Lopez-Herdoiza, Stephanie Bauché, Baptiste Wilmet, Caroline Le Duigou, Delphine Roussel, Magali Frah, Jonas Béal, Gabin Devely, Susana Boluda, Petra Frick, Delphine Bouteiller, Sébastien Dussaud, Pierre Guillabert, Carine Dalle, Magali Dumont, Agnes Camuzat, Dario Saracino, Mathieu Barbier, Gaelle Bruneteau, Phillippe Ravassard, Manuela Neumann, Sophie Nicole, Isabelle Le Ber, Alexis Brice, Morwena Latouche
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The GGGGCC intronic repeat expansion within C9ORF72 is the most common genetic cause of ALS and FTD. This mutation results in toxic gain of function through accumulation of expanded RNA foci and aggregation of abnormally translated dipeptide repeat p
Externí odkaz:
https://doaj.org/article/cf47ec065e0e43cbbe6e3408fa24d68b
Autor:
Aurélie Hanin, Paul Baudin, Sophie Demeret, Delphine Roussel, Sarah Lecas, Elisa Teyssou, Maria Damiano, David Luis, Virginie Lambrecq, Valerio Frazzini, Maxens Decavèle, Isabelle Plu, Dominique Bonnefont-Rousselot, Randa Bittar, Foudil Lamari, Vincent Navarro
Publikováno v:
Neurobiology of Disease, Vol 154, Iss , Pp 105346- (2021)
The understanding of the excitotoxic processes associated with a severe status epilepticus (SE) is of major importance.Changes of brain cholesterol homeostasis is an emerging candidate for excitotoxicity. We conducted an overall analysis of the chole
Externí odkaz:
https://doaj.org/article/45b17a83c4894d01a887e3b960dc1a79
Autor:
Elisa Teyssou, Laura Chartier, Delphine Roussel, Nirma D. Perera, Ivan Nemazanyy, Dominique Langui, Mélanie Albert, Thierry Larmonier, Safaa Saker, François Salachas, Pierre-François Pradat, Vincent Meininger, Philippe Ravassard, Francine Côté, Christian S. Lobsiger, Séverine Boillée, Bradley J. Turner, Danielle Seilhean, Stéphanie Millecamps
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5694 (2022)
Mutations in profilin 1 (PFN1) have been identified in rare familial cases of Amyotrophic Lateral Sclerosis (ALS). PFN1 is involved in multiple pathways that could intervene in ALS pathology. However, the specific pathogenic role of PFN1 mutations in
Externí odkaz:
https://doaj.org/article/d755c887523b42e6bf965626df96c24f
Autor:
Hélène Cwerman-Thibault, Christophe Lechauve, Sébastien Augustin, Delphine Roussel, Élodie Reboussin, Ammara Mohammad, Julie Degardin-Chicaud, Manuel Simonutti, Hong Liang, Françoise Brignole-Baudouin, Anne Maron, Thomas Debeir, Marisol Corral-Debrinski
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 200-220 (2017)
Mitochondrial dysfunction is responsible for hereditary optic neuropathies. We wished to determine whether preserving mitochondrial bioenergetics could prevent optic neuropathy in a reliable model of glaucoma. DBA/2J mice exhibit elevated intraocular
Externí odkaz:
https://doaj.org/article/d1a0ab37db8e4c718df48d2d936645ef
Autor:
Elise Marsan, Saeko Ishida, Adrien Schramm, Sarah Weckhuysen, Giuseppe Muraca, Sarah Lecas, Ning Liang, Caroline Treins, Mario Pende, Delphine Roussel, Michel Le Van Quyen, Tomoji Mashimo, Takehito Kaneko, Takashi Yamamoto, Tetsushi Sakuma, Séverine Mahon, Richard Miles, Eric Leguern, Stéphane Charpier, Stéphanie Baulac
Publikováno v:
Neurobiology of Disease, Vol 89, Iss , Pp 180-189 (2016)
DEP-domain containing 5 (DEPDC5), encoding a repressor of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway, has recently emerged as a major gene mutated in familial focal epilepsies and focal cortical dysplasia. Here we establ
Externí odkaz:
https://doaj.org/article/848e02bb7fa74f6fb765b3d6bcd24fad
Autor:
Emilie Lyne Saussereau, Delphine Roussel, Siradiou Diallo, Laurent Debarbieux, Aleksander Edelman, Isabelle Sermet-Gaudelus
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57317 (2013)
BACKGROUND: Treatments designed to correct cystic fibrosis transmembrane conductance regulator (CFTR) defects must first be evaluated in preclinical experiments in the mouse model of cystic fibrosis (CF). Mice nasal mucosa mimics the bioelectric defe
Externí odkaz:
https://doaj.org/article/dad98dc64fbe4353a9570af0fdb65d26
Autor:
Bertrand Mathon, Vincent Navarro, Sarah Lecas, Delphine Roussel, Stéphane Charpier, Alexandre Carpentier
Publikováno v:
Ultrasound in Medicine & Biology. 49:1327-1336
Publikováno v:
Psychiatric Services. 73:467-469
PRISM (Projet Reaffiliation Itinerance Sante Mentale [Homelessness Mental Health Reaffiliation Project]) is a clinical service developed through partnerships between shelters and the publicly funde...
Publikováno v:
Epilepsy & Behavior. 141:109133
Publikováno v:
eneuro. 10:ENEURO.0267-22.2023
Autoimmune encephalitis (AIE) associated with antibodies directed against the leucine-rich glioma inactivated 1 (LGI1) protein is the second most common AIE and is responsible for deleterious neocortical and limbic epileptic seizures. Previous studie