Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Delphine Marchaud"'
Autor:
Yvonne Rosiaux, Jean-Michel Girard, Delphine Marchaud, Amandine Forest, Carole Deleglise, Liz Sheehan
Publikováno v:
Journal of Drug Delivery Science and Technology. 48:437-449
Lipid coating in a high shear blender without heating and complex spray mechanism was investigated as a simplified approach to hot melt coating in a fluid bed device. Potassium chloride was coated with 20% glyceryl distearate using both processes. Mi
Autor:
Justin M. Keen, James W. McGinity, Justin R. Hughey, Vincent Jannin, Ryan C. Bennett, Connor J. Foley, Yvonne Rosiaux, Delphine Marchaud
Publikováno v:
International Journal of Pharmaceutics. 487:72-80
Interest in granulation processes using twin screw extrusion machines is rapidly growing. The primary objectives of this study were to develop a continuous granulation process for direct production of granules using this technique with glyceryl behen
Autor:
Hassan Benameur, Colin W. Pouton, Marilyn Calderone, Eduardo Jule, Anette Müllertz, Jan Vertommen, Vincent Jannin, Frédéric Carrière, Annabel Igonin, Philip Jonas Sassene, Christopher J.H. Porter, Hywel David Williams, Anette Partheil, Delphine Marchaud, Jean-Claude Bakala-N'Goma, Karen Kleberg, Mario Maio, Ross Blundell
Publikováno v:
The AAPS Journal. 16:1344-1357
The impact of pancreatin and calcium addition on a wide array of lipid-based formulations (LBFs) during in vitro lipolysis, with regard to digestion rates and distribution of the model drug danazol, was investigated. Pancreatin primarily affected the
Publikováno v:
Journal of Controlled Release. 175:63-71
A mechanistically realistic mathematical model is presented allowing for the quantification of niacin release from lipid tablets, based on glyceryl dibehenate. The systems were prepared either by direct compression or via hot-melt extrusion/grinding/
Autor:
Vincent Jannin, Colin W. Pouton, Mario Maio, Hassan Benameur, Christopher J.H. Porter, Annabel Igonin, Anette Müllertz, Philip Jonas Sassene, Jean-Claude Bakala-N'Goma, Anette Partheil, Marilyn Calderone, Frédéric Carrière, Jan Vertommen, Delphine Marchaud, Ross Blundell, Hywel David Williams, Karen Kleberg, Eduardo Jule
Publikováno v:
Journal of Pharmaceutical Sciences. 101:3360-3380
The Lipid Formulation Classification System Consortium is an industry-academia collaboration, established to develop standardized in vitro methods for the assessment of lipid-based formulations (LBFs). In this first publication, baseline conditions f
Publikováno v:
Drug Development and Industrial Pharmacy. 38:1068-1076
Sustained-release mini-tablets are a potentially suitable for paediatric drug delivery or as multi-particulate dosage forms.To evaluate the potential for developing lipophilic matrix mini-tablets and to assess the effects of Compritol® 888 ATO conce
Publikováno v:
Journal of Pharmaceutical Sciences. 99:262-274
The production and physicochemical characterisation of spray chilled Gelucire 50/13 microspheres is described with a view to improving the dissolution of a poorly water-soluble drug, piroxicam, and understanding the fundamental mechanisms associated
Publikováno v:
Drug development and industrial pharmacy. 41(10)
Niacin (vitamin B3) is a micronized active pharmaceutical ingredient (API) with poor flow properties making the production of high-dose sustained-release tablets by direct compression a challenge.We evaluated various wet granulation processes as a si
Publikováno v:
Excipient Applications in Formulation Design and Drug Delivery ISBN: 9783319202051
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aafb17472e2bd5c9a43478b3fcb8888
https://doi.org/10.1007/978-3-319-20206-8_9
https://doi.org/10.1007/978-3-319-20206-8_9
Autor:
Delphine Marchaud, Ryan C. Bennett, James W. McGinity, Yvonne Rosiaux, Justin R. Hughey, Vincent Jannin, Justin M. Keen
Publikováno v:
Molecular pharmaceutics. 12(1)
The objective of this study was to evaluate the use of glyceryl behenate as a plasticizer and release modifier in solid dispersion systems containing itraconazole and carbamazepine. Amorphous solid dispersions of high molecular weight polyvinylpyrrol