Two functionally distinct heme/iron transport systems are virulence determinants of the fish pathogen Flavobacterium psychrophilum

Autor: Yueying Zhu, Delphine Lechardeur, Jean-François Bernardet, Brigitte Kerouault, Cyprien Guérin, Dimitri Rigaudeau, Pierre Nicolas, Eric Duchaud, Tatiana Rochat

Publikováno v: Virulence, Vol 13, Iss 1, Pp 1221-1241 (2022)

Bacterial pathogens have a critical impact on aquaculture, a sector that accounts for half of the human fish consumption. Flavobacterium psychrophilum (phylum Bacteroidetes) is responsible for bacterial cold-water disease in salmonids worldwide. The

Externí odkaz: https://doaj.org/article/795ed96466d9448187e7cc3e4abd46c6

Two coregulated efflux transporters modulate intracellular heme and protoporphyrin IX availability in Streptococcus agalactiae.

Autor: Annabelle Fernandez, Delphine Lechardeur, Aurélie Derré-Bobillot, Elisabeth Couvé, Philippe Gaudu, Alexandra Gruss

Publikováno v: PLoS Pathogens, Vol 6, Iss 4, p e1000860 (2010)

Streptococcus agalactiae is a major neonatal pathogen whose infectious route involves septicemia. This pathogen does not synthesize heme, but scavenges it from blood to activate a respiration metabolism, which increases bacterial cell density and is

Externí odkaz: https://doaj.org/article/b5c5622ce08e4f2a9c88c7e821d6a813

A novel Enterococcus faecalis heme transport regulator (FhtR) is a heme sensor in the gastrointestinal tract

Autor: Pascal Arnoux, Alain Boussac, Emeline Ostyn, Damien Lipuma, Delphine Lechardeur, Vincent Saillant, Hugo Guerin, Géraldine Brandelet, Laetitia Joubert

Enterococcus faecalis is a commensal Gram-positive pathogen found in the intestines of mammals, and is also a leading cause of severe infections occurring mainly among antibiotic-treated dysbiotic hospitalized patients. Like most intestinal bacteria,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4304ddb4b82f5d133f94e83bf619461e
https://hal.inrae.fr/hal-03352408

Genetics of Lactococci

Autor: Karin Hammer, Delphine Lechardeur, Peter Ruhdal Jensen, Yuji Yamamoto, Alexandra Gruss, Philippe Gaudu

Publikováno v: Gram-Positive Pathogens
Gaudu, P, Yamamoto, Y, Jensen, P R, Hammer, K, Lechardeur, D & Gruss, A 2019, ' Genetics of Lactococci ', Microbiology Spectrum, vol. 7, no. 4 . https://doi.org/10.1128/microbiolspec.GPP3-0035-2018
Microbiology Spectrum
Microbiology Spectrum, American Society for Microbiology, 2019, 7, ⟨10.1128/microbiolspec.gpp3-0035-2018⟩
Microbiology Spectrum, American Society for Microbiology, 2019, 7 (4), ⟨10.1128/microbiolspec.GPP3-0035-2018⟩

Lactococcus lactis is the best characterized species among the lactococci, and among the most consumed food-fermenting bacteria worldwide. Thanks to their importance in industrialized food production, lactococci are among the lead bacteria understood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40dac9e6edef89ed5244cbd919ffb402
https://doi.org/10.1128/microbiolspec.gpp3-0035-2018

Respiration, a strategy to avoid oxidative stress in Lactococcus lactis, is regulated by the heme status

Autor: Philippe Gaudu, Gilles Lamberet, Annabelle Fernandez, Aurélie Derré-Bobillot, Bénédicte Cesselin, Yuji Yamamoto, Delphine Lechardeur, Martin Bastian Pedersen, Christel Garrigues

Publikováno v: Japanese Journal of Lactic Acid Bacteria. 21:10-15

Lactic acid bacteria (LAB) species like L. lactis are traditionally considered as obligate fermentative bacteria because even in aerobiosis they use sugar degradation for substrate-level phosphorylation, i.e. ATP production. However, recent studies r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46ed2c577f6e4da7fc09dd210dddc683
https://doi.org/10.4109/jslab.21.10