Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Delphine Guilligay"'
Publikováno v:
Viruses, Vol 15, Iss 2, p 558 (2023)
The SARS-CoV-2 pandemic has again shown that structural biology plays an important role in understanding biological mechanisms and exploiting structural data for therapeutic interventions. Notably, previous work on SARS-related glycoproteins has pave
Externí odkaz:
https://doaj.org/article/ee41b50dc1b54fb7bc4c964674a4a37c
Autor:
Christophe Caillat, Delphine Guilligay, Johana Torralba, Nikolas Friedrich, Jose L Nieva, Alexandra Trkola, Christophe J Chipot, François L Dehez, Winfried Weissenhorn
Publikováno v:
eLife, Vol 10 (2021)
The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate state by an MPER-specifi
Externí odkaz:
https://doaj.org/article/c1f8eb01d322414cb7d10e348e2d38dc
Publikováno v:
Viruses, Vol 12, Iss 11, p 1210 (2020)
HIV-1 vaccine research has obtained an enormous boost since the discovery of many broadly neutralizing antibodies (bnAbs) targeting all accessible sites on the HIV-1 envelope glycoprotein (Env). This in turn facilitated high-resolution structures of
Externí odkaz:
https://doaj.org/article/fdf85a1e9e054c7c87277dadd688dbf6
Autor:
Delphine Guilligay, Jan Kadlec, Thibaut Crépin, Thomas Lunardi, Denis Bouvier, Georg Kochs, Rob W H Ruigrok, Stephen Cusack
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84973 (2014)
Orthomyxovirus Influenza A virus (IAV) heterotrimeric polymerase performs transcription of viral mRNAs by cap-snatching, which involves generation of capped primers by host pre-mRNA binding via the PB2 subunit cap-binding site and cleavage 10-13 nucl
Externí odkaz:
https://doaj.org/article/d352208700df4855855c26107ef1e3eb
Autor:
Franck Tarendeau, Thibaut Crepin, Delphine Guilligay, Rob W H Ruigrok, Stephen Cusack, Darren J Hart
Publikováno v:
PLoS Pathogens, Vol 4, Iss 8, p e1000136 (2008)
Understanding how avian influenza viruses adapt to human hosts is critical for the monitoring and prevention of future pandemics. Host specificity is determined by multiple sites in different viral proteins, and mutation of only a limited number of t
Externí odkaz:
https://doaj.org/article/361942610ca84785807c834f399f9449
Autor:
Kimi Azad, Delphine Guilligay, Cecile Boscheron, Sourav Maity, Nicola De Franceschi, Guidenn Sulbaran, Gregory Effantin, Haiyan Wang, Jean-Philippe Kleman, Patricia Bassereau, Guy Schoehn, Wouter H. Roos, Ambroise Desfosses, Winfried Weissenhorn
Publikováno v:
Nature Structural and Molecular Biology, 30, 81-90. Nature Publishing Group
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2022, 30 (1), pp.81-90. ⟨10.1038/s41594-022-00867-8⟩
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2022, 30 (1), pp.81-90. ⟨10.1038/s41594-022-00867-8⟩
International audience; The endosomal sorting complex required for transport (ESCRT) is a highly conserved protein machinery that drives a divers set of physiological and pathological membrane remodeling processes. However, the structural basis of ES
Autor:
Sylvie, Chenavas, Delphine, Guilligay, Stephen, Cusack, Darren J, Hart, Rob W H, Ruigrok, Thibaut, Crépin
Publikováno v:
Virologie (Montrouge, France). 14(6)
Influenza virus polymerase transcribes and replicates the viral RNA genome within the context of a ribonucleoprotein complex that has been hitherto remarkably intractable to structural analysis. In the last three years, crystal structures of independ
Autor:
Kimi Azad, Delphine Guilligay, Cecile Boscheron, Sourav Maity, Nicola De Franceschi, Guidenn Sulbaran, Gregory Effantin, Haiyan Wang, Jean-Philippe Kleman, Patricia Bassereau, Guy Schoehn, Ambroise Desfosses, Winfried Weissenhorn
The endosomal sorting complex required for transport (ESCRT) is a highly conserved protein machinery that drives a divers set of physiological and pathological membrane remodeling processes. However, the structural basis of ESCRT-III polymers stabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd3000df25e9382f1abdadfc7783ba1d
https://doi.org/10.1101/2022.04.12.487901
https://doi.org/10.1101/2022.04.12.487901
Autor:
Isabelle Bally, Judith A. Burger, Rogier W. Sanders, M. Buisson, Wesley Gros, Pascal Poignard, Axelle Amen, Roger Le Grand, Daphna Fenel, Francis Relouzat, Guy Schoehn, Camille Bouillier, Vanessa Contreras, Nicole M. Thielens, Julien Lemaitre, Franck Fieschi, Guidenn Sulbaran, Sylvie van der Werf, Anne-Sophie Gallouet, Nathalie Dereuddre-Bosquet, Winfried Weissenhorn, Romain Marlin, Michel Thépaut, Thibaut Naninck, Delphine Guilligay, Sebastian Dergan Dylon, Marit J. van Gils, Pauline Maisonnasse, Meliawati Poniman
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, 2022, 3 (2), pp.100528. ⟨10.1016/j.xcrm.2022.100528⟩
Cell Reports Medicine, 3(2):100528. Cell Press
Cell Reports Medicine, 2022, 3 (2), pp.100528. ⟨10.1016/j.xcrm.2022.100528⟩
Cell Reports Medicine, 3(2):100528. Cell Press
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused an ongoing global health crisis. Here, we present as a vaccine candidate synthetic SARS-CoV-2 spike (S) glycoprotein-coated lipid vesicles that resemble virus-like p
Autor:
José L. Nieva, Winfried Weissenhorn, Nikolas Friedrich, Christophe Caillat, Christophe Chipot, Alexandra Trkola, François Dehez, Johana Torralba, Delphine Guilligay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf94512d9568a1b32ba3636f63b7b7e3
https://doi.org/10.7554/elife.65005.sa2
https://doi.org/10.7554/elife.65005.sa2