Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Delphine Fessart"'
Autor:
Simon Pernot, Mercedes Tomé, Isabel Galeano-Otero, Serge Evrard, Iker Badiola, Frederic Delom, Delphine Fessart, Tarik Smani, Geraldine Siegfried, Bruno O. Villoutreix, Abdel-Majid Khatib
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The overexpression of the immunoinhibitory receptor programmed death-1 (PD1) on T-cells is involved in immune evasion in cancer. The use of anti-PD-1/PDL-1 strategy has deeply changed the therapies of cancers and patient survival. However, their effi
Externí odkaz:
https://doaj.org/article/90571bd8e03445089bd4c69afb1017e6
Autor:
Delphine Fessart, Jacques Robert, Cecile Hartog, Eric Chevet, Frederic Delom, Guillaume Babin
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Abstract Epithelial ovarian cancer (EOC) is the most common gynecologic disorder. Even with the recent progresses made towards the use of new therapeutics, it still represents the most lethal gynecologic malignancy in women from developed countries.
Externí odkaz:
https://doaj.org/article/37c4339ea8cd4cdf8db4292c9c13bb33
Publikováno v:
Open Biology, Vol 12, Iss 7 (2022)
The AGR2 and AGR3 genes have been shown by numerous groups to be functionally associated with adenocarcinoma progression and metastasis. In this paper, we explore the data available in databases concerning genomic and transcriptomic features of these
Externí odkaz:
https://doaj.org/article/2c54ffa3206f43e58d32b3f1a1f46ac1
Autor:
Marion Maurel, Joanna Obacz, Tony Avril, Yong‐Ping Ding, Olga Papadodima, Xavier Treton, Fanny Daniel, Eleftherios Pilalis, Johanna Hörberg, Wenyang Hou, Marie‐Claude Beauchamp, Julien Tourneur‐Marsille, Dominique Cazals‐Hatem, Lucia Sommerova, Afshin Samali, Jan Tavernier, Roman Hrstka, Aurélien Dupont, Delphine Fessart, Frédéric Delom, Martin E Fernandez‐Zapico, Gregor Jansen, Leif A Eriksson, David Y Thomas, Loydie Jerome‐Majewska, Ted Hupp, Aristotelis Chatziioannou, Eric Chevet, Eric Ogier‐Denis
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 6, Pp n/a-n/a (2019)
Abstract Anterior gradient 2 (AGR2) is a dimeric protein disulfide isomerase family member involved in the regulation of protein quality control in the endoplasmic reticulum (ER). Mouse AGR2 deletion increases intestinal inflammation and promotes the
Externí odkaz:
https://doaj.org/article/2b0499d0c4e74f49840a1110c75b673e
Autor:
Delphine Fessart, Charlotte Domblides, Tony Avril, Leif A Eriksson, Hugues Begueret, Raphael Pineau, Camille Malrieux, Nathalie Dugot-Senant, Carlo Lucchesi, Eric Chevet, Frederic Delom
Publikováno v:
eLife, Vol 5 (2016)
The extracellular matrix (ECM) plays an instrumental role in determining the spatial orientation of epithelial polarity and the formation of lumens in glandular tissues during morphogenesis. Here, we show that the Endoplasmic Reticulum (ER)-resident
Externí odkaz:
https://doaj.org/article/3876518ea92442c383684c20fc26b282
Autor:
Frederic Delom, Delphine Fessart
Publikováno v:
International Journal of Cell Biology, Vol 2011 (2011)
The process by which G protein-coupled receptors (GPCRs) are internalized through the clathrin-coated vesicles involves interactions of multifunctional adaptor proteins. These interactions are tightly controlled by phosphorylation and dephosphorylati
Externí odkaz:
https://doaj.org/article/c8882cc5802c450e872f368cb536a3fc
Autor:
Abdel-Majid Khatib, Serge Evrard, Geraldine Siegfried, Isabelle Soubeyran, Julie Déchanet-Merville, François Ghiringhelli, Juan Antonio Rosado, Mariane Fonck, Dominique Bechade, Vincent Pitard, Frédéric Delom, Delphine Fessart, Amandine Mouchard, Marielle Dubreuil, Yannick Leger, Jone Olaizola, José Javier López, Fabienne Soulet, Angela Pappalardo, Mercedes Tomé
Key resources Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdaa2bc9221ad532dec1cc98c438647
https://doi.org/10.1158/0008-5472.22421879.v1
https://doi.org/10.1158/0008-5472.22421879.v1
Autor:
Abdel-Majid Khatib, Serge Evrard, Geraldine Siegfried, Isabelle Soubeyran, Julie Déchanet-Merville, François Ghiringhelli, Juan Antonio Rosado, Mariane Fonck, Dominique Bechade, Vincent Pitard, Frédéric Delom, Delphine Fessart, Amandine Mouchard, Marielle Dubreuil, Yannick Leger, Jone Olaizola, José Javier López, Fabienne Soulet, Angela Pappalardo, Mercedes Tomé
PCs expression in T cells and effect of PC inhibition on PD-1 expression, T cell signaling, survival and cytotoxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151b2fd6e70a2d5e93568ab58cb78fef
https://doi.org/10.1158/0008-5472.22421891
https://doi.org/10.1158/0008-5472.22421891
Autor:
Abdel-Majid Khatib, Serge Evrard, Geraldine Siegfried, Isabelle Soubeyran, Julie Déchanet-Merville, François Ghiringhelli, Juan Antonio Rosado, Mariane Fonck, Dominique Bechade, Vincent Pitard, Frédéric Delom, Delphine Fessart, Amandine Mouchard, Marielle Dubreuil, Yannick Leger, Jone Olaizola, José Javier López, Fabienne Soulet, Angela Pappalardo, Mercedes Tomé
Detailed description of the methodology performed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c38b5eb5b57e37523a11af143cac705
https://doi.org/10.1158/0008-5472.22421888
https://doi.org/10.1158/0008-5472.22421888
Autor:
Abdel-Majid Khatib, Serge Evrard, Geraldine Siegfried, Isabelle Soubeyran, Julie Déchanet-Merville, François Ghiringhelli, Juan Antonio Rosado, Mariane Fonck, Dominique Bechade, Vincent Pitard, Frédéric Delom, Delphine Fessart, Amandine Mouchard, Marielle Dubreuil, Yannick Leger, Jone Olaizola, José Javier López, Fabienne Soulet, Angela Pappalardo, Mercedes Tomé
Proprotein convertases (PC) activate precursor proteins that play crucial roles in various cancers. In this study, we investigated whether PC enzyme activity is required for expression of the checkpoint protein programmed cell death protein 1 (PD-1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6e02ca335873e83d51289b9d5d75790
https://doi.org/10.1158/0008-5472.c.6511064.v1
https://doi.org/10.1158/0008-5472.c.6511064.v1