Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Delphine El Mehdi"'
Publikováno v:
Journal of clinical medicine. 11(10)
Immunoglobulin A nephropathy (IgAN) is a rare autoimmune disorder and the leading cause of biopsy-reported glomerulonephritis (GN) worldwide. Disease progression is driven by the formation and deposition of immune complexes composed of galactose-defi
Autor:
David S. Boyer, Cedric G. Francois, Felix Grassmann, Delphine El Mehdi, Bernhard H. F. Weber, Philip J. Rosenfeld, Ramiro Ribeiro, Jason S. Slakter, Robert Y. Kim, Carol Chung, David Liao, Jeffrey S. Heier, Prema Abraham, David M. Brown, Charles C. Wykoff, Federico Grossi, Monica Gerber, Mohamed Hamdani, Lawrence J. Singerman, Pascal Deschatelets, Peter Nuernberg
Publikováno v:
Ophthalmology. 127:186-195
Objective Geographic atrophy (GA), a late stage of age-related macular degeneration, is a major cause of irreversible blindness. Even while central visual acuity remains relatively well preserved, GA often causes considerable compromise of visual fun
Autor:
Carl Di Casoli, Cedric G. Francois, Federico Grossi, Robert A. Brodsky, Ilene C. Weitz, Eloy Roman, Delphine El Mehdi, Vivek R. Sharma, Jaroslaw P. Maciejewski, Lisa Tan, Pascal Deschatelets, Carlos M. de Castro
Publikováno v:
American Journal of Hematology
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired, life‐threatening hematologic disease characterized by chronic complement‐mediated hemolysis and thrombosis. Despite treatment with eculizumab, a C5 inhibitor, 72% of individuals remain ane
Autor:
Cedric G. Francois, Dave Singh, Lisa Tan, Thomas Southworth, Federico Gross, Delphine El Mehdi, Carolina Vega, Helen Richardson, Pascal Deschatelets, Caroline Pattwell
Publikováno v:
Airway Cell Biology and Immunopathology.
Background: Complement proteins C3a and C5a are chemoattractants for neutrophils and macrophages, and may increase these cells in COPD lungs. Previous studies have shown that C5a is higher in COPD patients compared to controls and negatively correlat
Autor:
Michel Aubier, Isabelle Mosnier, Martine Grandsaigne, Benoit Feger, Delphine El Mehdi, Jean-Marie Zahm, Laurent Benayoun, Marie-Christine Dombret, Joël Depondt, Marina Pretolani, Anne Druilhe
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 38:276-282
Abnormal epithelial repair to damage participates in airway remodeling in asthma by the paracrine regulation of mesenchymal cell functions. Retinoids control epithelial functions through nuclear retinoic acid receptor (RAR) and retinoid X receptor (R
Autor:
Pascal Deschatelets, Humphrey Pullon, Carolina Vega, Federico Grossi, Delphine El Mehdi, Lisa Tan, Cedric G. Francois
Publikováno v:
Molecular Immunology. 89:115
Autor:
Delphine El Mehdi, Christina B. Clark, Madhavi J. Rane, Leroy R. Sachleben, Cynthia J. Miller, Evelyne Gozal
Heat shock protein 90 (Hsp90) is a chaperone protein regulating PC-12 cell survival by binding and stabilizing Akt, Raf-1, and Cdc37. Hsp90 inhibitor geldanamycin (GA) cytotoxicity has been attributed to the disruption of Hsp90 binding, and the contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4521f3adc6294bc4a0001cb4ad29e45e
https://europepmc.org/articles/PMC2767391/
https://europepmc.org/articles/PMC2767391/
Autor:
Ulrich Blank, Marina Pretolani, Séverine Pfirsch, Claudine Guérin-Marchand, Delphine El Mehdi, Yutaka Kanamaru, Renato C. Monteiro, Houda Tamouza
Publikováno v:
Blood. 109(1)
The IgA Fc receptor (FcalphaRI) has dual proinflammatory and anti-inflammatory functions that are transmitted through the immunoreceptor tyrosine-based activation motifs (ITAMs) of the associated FcRgamma subunit. Whereas the involvement of FcalphaRI