Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Delphine Demeestere"'
Autor:
Sofie Voet, Conor Mc Guire, Nora Hagemeyer, Arne Martens, Anna Schroeder, Peter Wieghofer, Carmen Daems, Ori Staszewski, Lieselotte Vande Walle, Marta Joana Costa Jordao, Mozes Sze, Hanna-Kaisa Vikkula, Delphine Demeestere, Griet Van Imschoot, Charlotte L. Scott, Esther Hoste, Amanda Gonçalves, Martin Guilliams, Saskia Lippens, Claude Libert, Roos E. Vandenbroucke, Ki-Wook Kim, Steffen Jung, Zsuzsanna Callaerts-Vegh, Patrick Callaerts, Joris de Wit, Mohamed Lamkanfi, Marco Prinz, Geert van Loo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
As resident macrophages of the brain, microglia are important for neuroinflammatory responses. This work shows that nuclear factor kappa B regulatory protein A20 is important for microglia activation and regulation during inflammation of the central
Externí odkaz:
https://doaj.org/article/3142b0c70aa74f90b3c6f5b5f17ce066
Autor:
Sriram Balusu, Elien Van Wonterghem, Riet De Rycke, Koen Raemdonck, Stephan Stremersch, Kris Gevaert, Marjana Brkic, Delphine Demeestere, Valerie Vanhooren, An Hendrix, Claude Libert, Roosmarijn E Vandenbroucke
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 10, Pp 1162-1183 (2016)
Abstract Here, we identified release of extracellular vesicles (EVs) by the choroid plexus epithelium (CPE) as a new mechanism of blood–brain communication. Systemic inflammation induced an increase in EVs and associated pro‐inflammatory miRNAs,
Externí odkaz:
https://doaj.org/article/6d64e554a98c44b7a2568b682bcc28e6
Autor:
Pinelopi Tsouni, Shahram Attarian, Andreas J. Steck, Beat Ernst, Delphine Demeestere, Thierry Kuntzer, Butrint Aliu, Ruben Herrendorff, Marie Théaudin, Emilie Seydoux, Pascal Hänggi, Tobias Derfuss, Emilien Delmont, Alexandre Brodovitch, Thomas Oberholzer, José Boucraut
Publikováno v:
Journal of Neurochemistry
Journal of Neurochemistry, 2020, 154 (5), pp.486-501. ⟨10.1111/jnc.15021⟩
Journal of neurochemistry, vol. 154, no. 5, pp. 486-501
Journal of Neurochemistry, 2020, 154 (5), pp.486-501. ⟨10.1111/jnc.15021⟩
Journal of neurochemistry, vol. 154, no. 5, pp. 486-501
Anti‐myelin‐associated glycoprotein (MAG) neuropathy is a disabling autoimmune peripheral neuropathy that is caused by circulating monoclonal IgM autoantibodies directed against the human natural killer‐1 (HNK‐1) epitope. This carbohydrate ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ff4ea3370840595b7131fb54bf2390
https://hal.science/hal-03596726
https://hal.science/hal-03596726
Autor:
Elien Van Wonterghem, Kris Gevaert, Roosmarijn E. Vandenbroucke, Riet De Rycke, Delphine Demeestere, Sriram Balusu, Valerie Vanhooren, An Hendrix, Marjana Brkic, Stephan Stremersch, Claude Libert, Koen Raemdonck
Publikováno v:
EMBO Molecular Medicine
EMBO MOLECULAR MEDICINE
EMBO MOLECULAR MEDICINE
Here, we identified release of extracellular vesicles (EVs) by the choroid plexus epithelium (CPE) as a new mechanism of blood–brain communication. Systemic inflammation induced an increase in EVs and associated pro‐inflammatory miRNAs, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067b521fd9bac5fb49e370b726cabd37
https://doi.org/10.15252/emmm.201606271
https://doi.org/10.15252/emmm.201606271
Autor:
Sophie Steeland, Paco Hulpiau, Elien Van Wonterghem, Jeroen Aerts, Griet Van Imschoot, Yvan Saeys, Jurgen Haustraete, Sylviane Dewaele, Claude Libert, Delphine Demeestere, Christoph Becker-Pauly, Nick Devoogdt, Rielana Wichert, Eline Dejonckheere, Lutgarde Arckens, Roosmarijn E. Vandenbroucke
Publikováno v:
Molecular Therapy. 24:890-902
A detrimental role for matrix metalloproteinase 8 (MMP8) has been identified in several pathological conditions, e.g., lethal hepatitis and the systemic inflammatory response syndrome. Since matrix MMP8-deficient mice are protected in the above-menti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4c111763750e88c1fb00c5799d9645
https://doi.org/10.1038/mt.2016.2
https://doi.org/10.1038/mt.2016.2
Autor:
Zsuzsanna Callaerts-Vegh, Mozes Sze, Hanna-Kaisa Vikkula, Conor Mc Guire, Delphine Demeestere, Joris de Wit, Saskia Lippens, Marco Prinz, Patrick Callaerts, Esther Hoste, Ori Staszewski, Charlotte L. Scott, Roosmarijn E. Vandenbroucke, Griet Van Imschoot, Arne Martens, Steffen Jung, Lieselotte Vande Walle, Nora Hagemeyer, Peter Wieghofer, Mohamed Lamkanfi, Sofie Voet, Amanda Gonçalves, Claude Libert, Marta Joana Costa Jordão, Martin Guilliams, Carmen Daems, Anna Schroeder, Geert van Loo, Ki-Wook Kim
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
NATURE COMMUNICATIONS
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Microglia, the mononuclear phagocytes of the central nervous system (CNS), are important for the maintenance of CNS homeostasis, but also critically contribute to CNS pathology. Here we demonstrate that the nuclear factor kappa B (NF-κB) regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c69e3d052433a5da1bc7ee1d07c7d3d
https://opus.bibliothek.uni-augsburg.de/opus4/files/89761/s41467-018-04376-5.pdf
https://opus.bibliothek.uni-augsburg.de/opus4/files/89761/s41467-018-04376-5.pdf
Autor:
Hélène B. Pfister, Samuel Frey, Fan Yang, Delphine Demeestere, Pascal Hänggi, Ruben Herrendorff, Nicole Schaeren-Wiemers, Andreas J. Steck, Fabienne Hunziker, Beat Ernst
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Anti-MAG (myelin-associated glycoprotein) neuropathy is a disabling autoimmune peripheral neuropathy caused by monoclonal IgM autoantibodies that recognize the carbohydrate epitope HNK-1 (human natural killer-1). This glycoepitope is highly expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5281a8c235c34d18a455483b1d0329cf
https://doi.org/10.1073/pnas.1619386114
https://doi.org/10.1073/pnas.1619386114
Publikováno v:
Brain, behavior, and immunity. 50
The choroid plexus (CP) comprises an epithelial monolayer that forms an important physical, enzymatic and immunologic barrier, called the blood-cerebrospinal fluid barrier (BCSFB). It is a highly vascularized organ located in the brain ventricles tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d071b3f3f8f3ae29dd770577abe689
https://pubmed.ncbi.nlm.nih.gov/26116435
https://pubmed.ncbi.nlm.nih.gov/26116435
Publikováno v:
Drug discovery today. 20(8)
The choroid plexus (CP) is a highly vascularized organ located in the brain ventricles and contains a single epithelial cell layer forming the blood-cerebrospinal fluid barrier (BCSFB). This barrier is crucial for immune surveillance in health and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959419eac58d38c50e47857bd5dc7b2a
https://pubmed.ncbi.nlm.nih.gov/25979470
https://pubmed.ncbi.nlm.nih.gov/25979470
Autor:
Ineke Vanlaere, Patrick Matthys, Filip Van Hauwermeiren, Conor Mc Guire, Elien Van Wonterghem, Claude Libert, Roosmarijn E. Vandenbroucke, Eline Dejonckheere, Georges Leclercq, Carlos López-Otín, Delphine Demeestere, Riet De Rycke, Philippe Van Lint, Leen Puimège, Cristina Campestre
Publikováno v:
SCOPUS
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
This work was supported by the agency for the Innovation by Science and Technology in Flanders,the Research Council of Ghent University, the Research Foundation Flanders, and the Interuniversity Attraction Poles Program of the Belgian Science Policy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95241082fbf48dbeede33a2ee9fb2b39
http://hdl.handle.net/10651/7033
http://hdl.handle.net/10651/7033