X-rays minibeam radiation therapy at a conventional irradiator: Pilot evaluation in F98-glioma bearing rats and dose calculations in a human phantom

Autor: Frederic Pouzoulet, Marine Le Dudal, Grégory Jouvion, Catherine Sebrié, Delphine Crépin, Yolanda Prezado, Marjorie Juchaux, Dalila Labiod, Elise Brisebard, Charlotte Lamirault, Marios Sotiropoulos, Laurène Jourdain

Publikováno v: Clinical and Translational Radiation Oncology
Clinical and Translational Radiation Oncology, 2021, 27, pp.44-49. ⟨10.1016/j.ctro.2021.01.001⟩
Clinical and Translational Radiation Oncology, Elsevier, 2021, 27, pp.44-49. ⟨10.1016/j.ctro.2021.01.001⟩
Clinical and Translational Radiation Oncology, Vol 27, Iss, Pp 44-49 (2021)

Highlights • Minibeam radiation therapy at a table top system widens the therapeutic window for high grade gliomas in rats. • The first evaluation of a possible treatment plan of X-rays MBRT is reported. • An upper dose threshold for normal tis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98207122c88c38cb735d656f66b8c9f2
https://hal.science/hal-03366784

Evaluation of skull optical clearing process for longitudinal non invasive optical imaging

Autor: Hirac Gurden, Haleh Soleimanzad, Frédéric Pain, Marjorie Juchaux, Delphine Crépin

Publikováno v: Neural Imaging and Sensing 2020.

We have evaluated in vitro and in vivo the efficiency and practicability of reversible optical clearing of the skull for minimally invasive, longitudinal imaging of the rodent brain. Firstly, in vitro experiments have been conducted on resected mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a1b87d252ca32bf1abb5214f5071ccc
https://doi.org/10.1117/12.2544298

Unexpected long-term protection of adult offspring born to high-fat fed dams against obesity induced by a sucrose-rich diet.

Autor: Odile Couvreur, Jacqueline Ferezou, Daniel Gripois, Colette Serougne, Delphine Crépin, Alain Aubourg, Arieh Gertler, Claire-Marie Vacher, Mohammed Taouis

Publikováno v: PLoS ONE, Vol 6, Iss 3, p e18043 (2011)

BACKGROUND: Metabolic and endocrine environment during early life is crucial for metabolic imprinting. When dams were fed a high fat diet (HF diet), rat offspring developed hypothalamic leptin resistance with lean phenotype when weaned on a normal di

Externí odkaz: https://doaj.org/article/211c05b6b7364f6ba8194d70c883d0c7

Central Resistin/TLR4 Impairs Adiponectin Signaling, Contributing to Insulin and FGF21 Resistance

Autor: Mohammed Taouis, Hamza Amine, Delphine Crépin, Yacir Benomar, Laure Riffault, Sarah Al Rifai, Arieh Gertler

Publikováno v: Diabetes
Diabetes, American Diabetes Association, 2016, 65 (4), pp.913-926. ⟨10.2337/db15-1029⟩

Adiponectin, an insulin-sensitizing hormone, and resistin, known to promote insulin resistance, constitute a potential link between obesity and type 2 diabetes. In addition, fibroblast growth factor (FGF)21 has effects similar to those of adiponectin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0095ea0e880a36fcf28e006359f0094
https://doi.org/10.2337/db15-1029

Milk-soluble formula increases food intake and reduces Il6 expression in elderly rat hypothalami

Autor: Hassina Ould Hamouda, Delphine Crépin, Yacir Benomar, Pascale Leruyet, Bernadette Delplanque, Mohammed Taouis, Laure Riffault, Cécile Bonhomme

Publikováno v: Journal of Endocrinology. 226:67-80

Malnutrition in the elderly is accompanied by several metabolic dysfunctions, especially alterations in energy homeostasis regulation and a loss of insulin responsiveness. Nutritional recommendations aim to enrich food with high protein and energy su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839959f3cc8431e1b3b7fa60b150046d
https://doi.org/10.1530/joe-15-0076