Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Delphine C, Malherbe"'
Autor:
Paige Fletcher, Chad S Clancy, Kyle L O'Donnell, Brianna M Doratt, Delphine C Malherbe, Joseph F Rhoderick, Friederike Feldmann, Patrick W Hanley, Ayato Takada, Ilhem Messaoudi, Andrea Marzi
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012290 (2024)
Taï Forest virus (TAFV) is a negative-sense RNA virus in the Filoviridae family. TAFV has caused only a single human infection, but several disease outbreaks in chimpanzees have been linked to this virus. Limited research has been done on this human
Externí odkaz:
https://doaj.org/article/6cdcafda9edb4689a6f82abbd530c61b
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionVaricella zoster virus (VZV) causes varicella and can reactivate as herpes zoster, and both diseases present a significant burden worldwide. However, the mechanisms by which VZV establishes latency in the sensory ganglia and disseminates
Externí odkaz:
https://doaj.org/article/09820a5f7f2d4f808a50e321bdd719dc
Autor:
Paige Fletcher, Kyle L. O’Donnell, Brianna M. Doratt, Delphine C. Malherbe, Chad S. Clancy, Joseph F. Rhoderick, Friederike Feldmann, Patrick W. Hanley, Thomas G. Ksiazek, Thomas W. Geisbert, Ilhem Messaoudi, Andrea Marzi
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Taï Forest virus (TAFV) is a lesser-known ebolavirus that causes lethal infections in chimpanzees and is responsible for a single human case. Limited research has been done on this human pathogen; however, with the recent emergence of filoviruses in
Externí odkaz:
https://doaj.org/article/f1a3f2fcd8214a4ba60d2e193a246435
Autor:
Shixia Wang, Chang Yi Wang, Hui-Kai Kuo, Wen-Jiun Peng, Juin-Hua Huang, Be-Shen Kuo, Feng Lin, Yaw-Jen Liu, Zhi Liu, Huang-Ting Wu, Shuang Ding, Kou-Liang Hou, Jennifer Cheng, Ya-Ting Yang, Ming-Han Jiang, Min-Sheng Wang, Tony Chen, Wei Guo Xia, Ed Lin, Chung Ho Hung, Hui-Jung Chen, Zhonghao Shih, Yi Ling Lin, Valorie Ryan, Mei Mei Hu, D. Gray Heppner, Delphine C. Malherbe, Sivakumar Periasamy, Natalia Kuzmina, Chandru Subramani, Michael Hellerstein, Thomas P. Monath, Alexander Rumyantsev, Alexander Bukreyev, Farshad Guirakhoo
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2724-2734 (2022)
The development of safe and effective vaccines to respond to COVID-19 pandemic/endemic remains a priority. We developed a novel subunit protein-peptide COVID-19 vaccine candidate (UB-612) composed of: (i) receptor binding domain of SARS-CoV-2 spike p
Externí odkaz:
https://doaj.org/article/d9e5af23b5ef47048009e734003b47bf
Autor:
Delphine C. Malherbe, Arban Domi, Mary J. Hauser, Caroline Atyeo, Stephanie Fischinger, Matthew A. Hyde, Julie M. Williams, Galit Alter, Farshad Guirakhoo, Alexander Bukreyev
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-7 (2022)
Abstract A new vectored vaccine MVA-VLP-SUDV was generated against Sudan ebolavirus (SUDV) combining the advantages of the immunogenicity of a live attenuated vaccine vector (Modified Vaccinia Ankara, MVA) with the authentic conformation of virus-lik
Externí odkaz:
https://doaj.org/article/879a977d02bd49479bcc0f56d51a4c07
Autor:
Svenja Weiss, Vincenza Itri, Ruimin Pan, Xunqing Jiang, Christina C. Luo, Lynn Morris, Delphine C. Malherbe, Philip Barnette, Jeff Alexander, Xiang-Peng Kong, Nancy L. Haigwood, Ann J. Hessell, Ralf Duerr, Susan Zolla-Pazner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here the authors show that an HIV vaccine in non-human primates that focuses antibodies on the V1V2 region of gp120 is superior to infection or immunization with whole envelope vaccines for inducing V1V2 antibodies with anti-viral functions that corr
Externí odkaz:
https://doaj.org/article/a623118e7a31438db01163d784cdf0fa
Autor:
Delphine C. Malherbe, Drishya Kurup, Christoph Wirblich, Adam J. Ronk, Chad Mire, Natalia Kuzmina, Noor Shaik, Sivakumar Periasamy, Matthew A. Hyde, Julie M. Williams, Pei-Yong Shi, Matthias J. Schnell, Alexander Bukreyev
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract The development of effective countermeasures against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for the COVID-19 pandemic, is a priority. We designed and produced ConVac, a replication-competent vesic
Externí odkaz:
https://doaj.org/article/ebf985f490e445e383c6a2b50cb40eb9
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Ancestral RNA polymerase III (Pol III) is a multi-subunit polymerase responsible for transcription of short non-coding RNA, such as double-stranded short interspersed nuclear elements (SINEs). Although SINE ncRNAs are generally transcriptionally repr
Externí odkaz:
https://doaj.org/article/e9ffe757586947b984c0ccdd7ec00f37
Autor:
Delphine C. Malherbe, Ilhem Messaoudi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Drinking alcohol, even in moderation, can affect the immune system. Studies have shown disproportionate effects of alcohol on circulating and tissue-resident myeloid cells (granulocytes, monocytes, macrophages, dendritic cells). These cells orchestra
Externí odkaz:
https://doaj.org/article/0f1af2520c9e4ccca43aec9523544757
Autor:
Clara T Schoeder, Pavlo Gilchuk, Amandeep K Sangha, Kaitlyn V Ledwitch, Delphine C Malherbe, Xuan Zhang, Elad Binshtein, Lauren E Williamson, Cristina E Martina, Jinhui Dong, Erica Armstrong, Rachel Sutton, Rachel Nargi, Jessica Rodriguez, Natalia Kuzmina, Brooke Fiala, Neil P King, Alexander Bukreyev, James E Crowe, Jens Meiler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010518 (2022)
The three human pathogenic ebolaviruses: Zaire (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) virus, cause severe disease with high fatality rates. Epitopes of ebolavirus glycoprotein (GP) recognized by antibodies with binding breadth for all three ebol
Externí odkaz:
https://doaj.org/article/83108648321c484bbf22f4df7b598b39