Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Delphine Boucreux"'
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Hepatitis C virus core variants isolated from liver tumor but not from adjacent non-tumor tissue interact with Smad3 and inhibit the TGF-β pathway
Autor: Christian Bréchot, Rodolphe Sobesky, Delphine Boucreux, Olivier Hermine, Nicole Pavio, Bertrand Arnulf, Serena Battaglia
Publikováno v: Oncogene. 24:6119-6132
Hepatitis C virus (HCV) is a major risk factor for human hepatocellular carcinoma (HCC) but the mechanisms underlying HCV-induced carcinogenesis are still poorly understood. We have hypothesized that viral variants, selected during long-term infectio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af97cb11779622beb30b3dd43cc37027
https://doi.org/10.1038/sj.onc.1208749
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2
Different hepatitis C virus nonstructural protein 3 (Ns3)-DNA[ndash ]expressing vaccines induce in HLA-A2.1 transgenic mice stable cytotoxic T lymphocytes that target one major epitope
Autor: Nathalie Renard, Anne Fournillier, Geneviève Inchauspé, Stéphanie Muguet, Delphine Boucreux, Yu-Chun Lone, Carine Brinster, François A. Lemonnier
Publikováno v: Hepatology. 34:1206-1217
The immunogenicity of the Hepatitis C virus (HCV) nonstructural protein 3 (NS3) was investigated using different DNA-based strategies and a preclinical mouse model transgenic for the HLA-A2.1 molecule. Plasmids expressing NS3 either as a wild-type pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e32687ed8d3e23c9c327017b9c59c7f
https://doi.org/10.1053/jhep.2001.29304
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3
Use of Conventional or Replicating Nucleic Acid-Based Vaccines and Recombinant Semliki Forest Virus-Derived Particles for the Induction of Immune Responses Against Hepatitis C Virus Core and E2 Antigens
Autor: I. Nakano, Christian Trepo, Peter Liljeström, C. Brinster, Y. Fukuda, Thomas F. Baumert, Nathalie Renard, A. Fournillier, Margaret Chen, Geneviève Inchauspe, O. Vidalin, Delphine Boucreux, Erik Depla
Publikováno v: Virology. 276(2):259-270
Replicating and nonreplicating nucleic acid-based vaccines as well as Semliki Forest-recombinant Viruses (rSFVs) were evaluated for the development of a vaccine against hepatitis C virus (HCV). Replicating SFV-DNA vaccines (pSFV) and rSFVs expressing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ed85d56b99fddb3c1f1549128748f5
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4
Mapping of the interacting domains of hepatitis C virus core protein and the double-stranded RNA-activated protein kinase PKR
Autor: Delphine Boucreux, Xue-Bing Yan, Zhi Chen, Nicole Pavio, Christian Bréchot, Serena Battaglia
Publikováno v: Virus research. 125(1)
Hepatitis C virus (HCV) core protein has been shown to exhibit several biological properties which suggest an important role in liver pathogenesis and carcinogenesis. During a previous study, we showed that core mutants, isolated from tumour, could d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108b813a7c631bc178a75abf6cef2c22
https://pubmed.ncbi.nlm.nih.gov/17267064
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5
Induction of Hepatitis C Virus E1 Envelope Protein-Specific Immune Response Can Be Enhanced by Mutation of N-Glycosylation Sites
Autor: Thomas Baumert, Geneviève Inchauspe, Delphine Boucreux, Anne Fournillier, Erik Depla, S. Muguet, D. Jacobs, Jean-Christophe Meunier, Czeslaw Wychowski
Deglycosylation of viral glycoproteins has been shown to influence the number of available epitopes and to modulate immune recognition of antigens. We investigated the role played by N-glycans in the immunogenicity of hepatitis C virus (HCV) E1 envel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899adbce38d212412554921c6b2a8f0c
https://europepmc.org/articles/PMC116104/
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