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of 4
pro vyhledávání: '"Delphine Baronnier"'
Publikováno v:
Cell Reports
Autor:
Christopher E V Wright, Takeshi Miyatsuka, Simona Chera, Melissa K Thomas, Daniel Oropeza, Valentina Cigliola, Simone Gupta, Delphine Baronnier, Mark A. Magnuson, Léon van Gurp, Luiza Ghila, Maike Sander, Anna B. Osipovich, Hideaki Kaneto, Pedro Luis Herrera, Fabrizio Thorel, Kenichiro Furuyama
Publikováno v:
Nature Cell Biology, Vol. 20, No 11 (2018) pp. 1267-1277
Nature cell biology, vol 20, iss 11
Nature cell biology
Nature cell biology, vol 20, iss 11
Nature cell biology
The mechanisms that restrict regeneration and maintain cell identity following injury are poorly characterized in higher vertebrates. Following β-cell loss, 1-2% of the glucagon-producing α-cells spontaneously engage in insulin production in mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6dc86f07b6d1da934836846fee1d2aa
https://archive-ouverte.unige.ch/unige:111714
https://archive-ouverte.unige.ch/unige:111714
Autor:
Patrice H. Lalive, Claire Bonal, Mahdia Benkhoucha, Caroline Pot, Martin E. Schwab, Delphine Baronnier, Pedro Luis Herrera
Publikováno v:
Diabetes
Diabetes, Vol. 62, No 5 (2013) pp. 1443-52
Diabetes, Vol. 62, No 5 (2013) pp. 1443-52
Type 2 diabetes (T2D) is characterized by β-cell dysfunction and the subsequent depletion of insulin production, usually in a context of increased peripheral insulin resistance. T2D patients are routinely treated with oral antidiabetic agents such a
Autor:
Simona Chera, Luiza Ghila, Frank Reimann, Fabrizio Thorel, Fiona M. Gribble, Kenichiro Furuyama, Valentina Cigliola, Guoqiang Gu, Jan N. Jensen, Delphine Baronnier, Pedro Luis Herrera
Publikováno v:
Nature, Vol. 514, No 7523 (2014) pp. 503-7
Nature
Nature
Total or near-total loss of insulin-producing β-cells occurs in type 1 diabetes. Restoration of insulin production in type 1 diabetes is thus a major medical challenge. We previously observed in mice in which β-cells are completely ablated that the