Výsledky vyhledávání - "Delphine Albrecht"

Chemo-Genetic Interactions Between Histone Modification and the Antiproliferation Drug AICAR Are Conserved in Yeast and Humans

Autor: Benoît Pinson, Johanna Ceschin, Florian Gueniot, Delphine Albrecht, Bertrand Daignan-Fornier, Jim Dompierre

Publikováno v: Genetics
Genetics, Genetics Society of America, 2016, 204 (4), pp.1447-1460. ⟨10.1534/genetics.116.192518⟩

Identifying synthetic lethal interactions has emerged as a promising new therapeutic approach aimed at targeting cancer cells directly. Here, we used the yeast Saccharomyces cerevisiae as a simple eukaryotic model to screen for mutations resulting in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980469a0384dba8cb831964a1cc81f54
https://doi.org/10.1534/genetics.116.192518

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Multiple chemo-genetic interactions between a toxic metabolite and the ubiquitin pathway in yeast

Autor: Johanna Ceschin, Christelle Saint-Marc, Benoît Pinson, Hans Caspar Hürlimann, Bertrand Daignan-Fornier, Delphine Albrecht

Publikováno v: Current Genetics
Current Genetics, Springer Verlag, 2018, 64 (6), pp.1275-1286. ⟨10.1007/s00294-018-0843-7⟩

AICAR is the precursor of ZMP, a metabolite with antiproliferative properties in yeast and human. We aim at understanding how AICAR (and its active form ZMP) affects essential cellular processes. In this work, we found that ZMP accumulation is synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668268804a0d9bf2b8eae378ee8068b7
https://pubmed.ncbi.nlm.nih.gov/29721631

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Disruption of Nucleotide Homeostasis by the Antiproliferative Drug 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside Monophosphate (AICAR)

Autor: Hans Caspar Hürlimann, Typhaine Violo, Johanna Ceschin, Delphine Albrecht, Christelle Saint-Marc, Bertrand Daignan-Fornier, Michel Moenner, Benoît Pinson

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2015, 290 (39), pp.23947-23959. ⟨10.1074/jbc.M115.656017⟩

5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside monophosphate (AICAR) is a natural metabolite with potent anti-proliferative and low energy mimetic properties. At high concentration, AICAR is toxic for yeast and mammalian cells, but the molecula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6ff1cfc4a2f1727eee63afeb890c44
https://pubmed.ncbi.nlm.nih.gov/26283791

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Guided assembly of tetramolecular G-quadruplexes

Autor: Olivier Piétrement, Jean-Louis Mergny, Jean-Pierre Aimé, Daniel Renčiuk, Phong Tran, Hiroshi Sugiyama, Liliya A. Yatsunyk, Delphine Albrecht, Jean-Michel Arbona

Publikováno v: ACS Nano
ACS Nano, 2013, 7 (7), pp.5701-5710. ⟨10.1021/NN402321G⟩
ACS Nano, American Chemical Society, 2013, 7 (7), pp.5701-5710. ⟨10.1021/NN402321G⟩

Nucleic acids are finding applications in nanotechnology as nanomaterials, mechanical devices, templates, and biosensors. G-quadruplex DNA, formed by π-π stacking of guanine (G) quartets, is an attractive alternative to regular B-DNA because of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fe0d3e13af6f59818188676ff370d6
https://pubmed.ncbi.nlm.nih.gov/23763613

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LE SPECTATEUR EN VEDETTE DANS LES ANECDOTES DRAMATIQUES DU XVIII E SIECLE

Autor: MARCHAND, Sophie

Publikováno v: Faire œuvre d'une réception. Portraits de spectateurs de théâtre (XVIe-XXIe siècles)
Delphine Albrecht, Lise Michel, Coline Piot. Faire œuvre d'une réception. Portraits de spectateurs de théâtre (XVIe-XXIe siècles), L'Entretemps, Coll. "Champ théâtral", pp.89-101, 2019

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::66b343c48d1a4ed25f490da4c39777e6
https://hal.sorbonne-universite.fr/hal-03312775

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