Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Delphine, Baud"'
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A target safety assessment of the potential toxicological risks of targeting plasmepsin IX/X for the treatment of malaria
Autor: Jane Barber, Ruth A. Roberts, Jean-Pierre Valentin, Delphine Baud, Claire Sadler, Phumzile Sikakana
Publikováno v: Toxicol Res (Camb)
The aspartic proteases plasmepsin IX/X are important antimalarial drug targets due to their specificity to the malaria parasite and their vital role as mediators of disease progression. Focusing on parasite-specific targets where no human homologue e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9eb55b2c764d7a95f9f39a4bbecde3
https://doi.org/10.1093/toxres/tfaa106
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5
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance
Autor: Mohammed H Cherkaoui-Rbati, Roland A. Cooper, Nina F. Gnädig, Iñigo Angulo-Barturen, Tomas Yeo, Sridevi Bashyam, Rintis Noviyanti, James M. Murithi, Gilles Courtemanche, Philip J. Rosenthal, María Belén Jiménez-Díaz, Laurent Sallé, Cécile Pascal, Rita Merino, Gilles Tuffal, Jutta Marfurt, Sergio Wittlin, Shivendra Singh, Marie José Cabanis, Lidiya Bebrevska, Jean Michel Augereau, Laura M. Sanz, Jean Michel Guillon, Sachel Mok, Paul Desert, Kelly Rubiano, Alain Pellet, Jacquin C. Niles, Guillaume Louit, Anne-Catrin Uhlemann, Nadir Bessila, Thierry Vermat, Simon Campbell, Didier Leroy, Tanguy Bozec, Jérôme Menegotto, Michel Doubovetzky, Xavier Boulenc, Benjamin Blasco, Nathalie Gobeau, Francisco-Javier Gamo, Sylvie Klieber, Elie Giraud, Jayan Joseph, Charisse Flerida A. Pasaje, Delphine Baud, Laurent Fraisse, Fanny Escudié, Jade Bath, Marie Françoise Nicolas, Mélanie Rouillier, David A. Fidock, Grennady Wirjanata, Ric N. Price, Patrick K Tumwebaze
The emergence and spread of Plasmodium falciparum resistance to first-line antimalarials creates an imperative to identify and develop potent preclinical candidates with distinct modes of action. Here, we report the identification of MMV688533, an ac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c2e27d8190f65306f8587a21d03126
https://ora.ox.ac.uk/objects/uuid:39d2c646-efac-4c3d-bdef-8cf1ff7f497f
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6
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to
Autor: James M, Murithi, Cécile, Pascal, Jade, Bath, Xavier, Boulenc, Nina F, Gnädig, Charisse Flerida A, Pasaje, Kelly, Rubiano, Tomas, Yeo, Sachel, Mok, Sylvie, Klieber, Paul, Desert, María Belén, Jiménez-Díaz, Jutta, Marfurt, Mélanie, Rouillier, Mohammed H, Cherkaoui-Rbati, Nathalie, Gobeau, Sergio, Wittlin, Anne-Catrin, Uhlemann, Ric N, Price, Grennady, Wirjanata, Rintis, Noviyanti, Patrick, Tumwebaze, Roland A, Cooper, Philip J, Rosenthal, Laura M, Sanz, Francisco Javier, Gamo, Jayan, Joseph, Shivendra, Singh, Sridevi, Bashyam, Jean Michel, Augereau, Elie, Giraud, Tanguy, Bozec, Thierry, Vermat, Gilles, Tuffal, Jean-Michel, Guillon, Jérôme, Menegotto, Laurent, Sallé, Guillaume, Louit, Marie-José, Cabanis, Marie Françoise, Nicolas, Michel, Doubovetzky, Rita, Merino, Nadir, Bessila, Iñigo, Angulo-Barturen, Delphine, Baud, Lidiya, Bebrevska, Fanny, Escudié, Jacquin C, Niles, Benjamin, Blasco, Simon, Campbell, Gilles, Courtemanche, Laurent, Fraisse, Alain, Pellet, David A, Fidock, Didier, Leroy
Publikováno v: Sci Transl Med
The emergence and spread of Plasmodium falciparum resistance to first-line antimalarials creates an imperative to identify and develop potent preclinical candidates with distinct modes of action. Here, we report the identification of MMV688533, an ac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f0efda724d23dde7d58c5a209b92e0ae
https://pubmed.ncbi.nlm.nih.gov/34290058
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8
Cell-free production, purification and characterization of human mitochondrial ADP/ATP carriers
Autor: Delphine Baud, Stéphanie Ravaud, Céline Juillan-Binard, Aleksandra Woznicka-Misaila, Eva Pebay-Peyroula
Publikováno v: Protein Expression and Purification
Protein Expression and Purification, Elsevier, 2018, 144, pp.46-54. ⟨10.1016/j.pep.2017.11.008⟩
Protein Expression and Purification, 2018, 144, pp.46-54. ⟨10.1016/j.pep.2017.11.008⟩
International audience; Mitochondrial Carriers (MCs) are responsible for fluent traffic of a variety of compounds that need to be shuttled via mitochondrial inner membranes to maintain cell metabolism. The ADP/ATP Carriers (AACs) are responsible for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b01bc2dc3085db36313c03815d91823
https://doi.org/10.1016/j.pep.2017.11.008
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9
Oligomeric States of the Detergent-solubilized Human Serum Paraoxonase (PON1)
Autor: Alice Fontaine, Patrick Masson, Delphine Baud, Eric Chabrières, Christine Ebel, Aude Echalier, David Stroebel, Freádeárique Renault, Freádeáric Borges, Marc le Maire, Denis Josse
Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2002, 277 (36), pp.33386-33397. ⟨10.1074/jbc.M200108200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2002, 277 (36), pp.33386-33397. ⟨10.1074/jbc.M200108200⟩
Human plasma paraoxonase (HuPON1) is a high density lipoprotein (HDL)-bound enzyme exhibiting antiatherogenic properties. The molecular basis for the binding specificity of HuPON1 to HDL has not been established. Isolation of HuPON1 from HDL requires
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfac45bf7927dde827307cb5e2a767a0
https://hal.univ-lorraine.fr/hal-02498300
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