Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Delma S, Childers"'
Autor:
Qinxi Ma, Arnab Pradhan, Ian Leaves, Emer Hickey, Elena Roselletti, Ivy Dambuza, Daniel E. Larcombe, Leandro Jose de Assis, Duncan Wilson, Lars P. Erwig, Mihai G. Netea, Delma S. Childers, Gordon D. Brown, Neil A.R. Gow, Alistair J.P. Brown
Publikováno v:
The Cell Surface, Vol 11, Iss , Pp 100128- (2024)
Host recognition of the pathogen-associated molecular pattern (PAMP), β-1,3-glucan, plays a major role in antifungal immunity. β-1,3-glucan is an essential component of the inner cell wall of the opportunistic pathogen Candida albicans. Most β-1,3
Externí odkaz:
https://doaj.org/article/246a9682c09641f7a0a0fda1cc487324
Autor:
Gabriela M. Avelar, Arnab Pradhan, Qinxi Ma, Emer Hickey, Ian Leaves, Corin Liddle, Alejandra V. Rodriguez Rondon, Ann-Kristin Kaune, Sophie Shaw, Corinne Maufrais, Natacha Sertour, Judith M. Bain, Daniel E. Larcombe, Leandro J. de Assis, Mihai G. Netea, Carol A. Munro, Delma S. Childers, Lars P. Erwig, Gordon D. Brown, Neil A. R. Gow, Marie-Elisabeth Bougnoux, Christophe d'Enfert, Alistair J. P. Brown
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Microbial species capable of co-existing with healthy individuals, such as the commensal fungus Candida albicans, exploit multifarious strategies to evade our immune defenses. These strategies include the masking of immunoinflammatory pathog
Externí odkaz:
https://doaj.org/article/a315d65d8db7474e9c59617b6af6132d
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Reference strains improve reproducibility by standardizing observations and methodology, which has ultimately led to important insights into fungal pathogenesis. However, recent investigations have highlighted significant genotypic and pheno
Externí odkaz:
https://doaj.org/article/3fceee2f499b4827aba31da14c3ff105
Autor:
Leandro José de Assis, Judith M. Bain, Corin Liddle, Ian Leaves, Christian Hacker, Roberta Peres da Silva, Raif Yuecel, Attila Bebes, David Stead, Delma S. Childers, Arnab Pradhan, Kevin Mackenzie, Katherine Lagree, Daniel E. Larcombe, Qinxi Ma, Gabriela Mol Avelar, Mihai G. Netea, Lars P. Erwig, Aaron P. Mitchell, Gordon D. Brown, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Candida albicans exists as a commensal of mucosal surfaces and the gastrointestinal tract without causing pathology. However, this fungus is also a common cause of mucosal and systemic infections when antifungal immune defenses become compro
Externí odkaz:
https://doaj.org/article/7eee21d07077458d862a678b6efa049c
Autor:
Gabriela M. Avelar, Ivy M. Dambuza, Liviana Ricci, Raif Yuecel, Kevin Mackenzie, Delma S. Childers, Judith M. Bain, Arnab Pradhan, Daniel E. Larcombe, Mihai G. Netea, Lars P. Erwig, Gordon D. Brown, Sylvia H. Duncan, Neil A.R. Gow, Alan W. Walker, Alistair J.P. Brown
Publikováno v:
The Cell Surface, Vol 8, Iss , Pp 100084- (2022)
The immunogenicity of Candida albicans cells is influenced by changes in the exposure of microbe-associated molecular patterns (MAMPs) on the fungal cell surface. Previously, the degree of exposure on the C. albicans cell surface of the immunoinflamm
Externí odkaz:
https://doaj.org/article/369d68d889004bc9b1d341433c89942b
Autor:
Delma S. Childers, Gabriela Mol Avelar, Judith M. Bain, Arnab Pradhan, Daniel E. Larcombe, Mihai G. Netea, Lars P. Erwig, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT The cell wall provides a major physical interface between fungal pathogens and their mammalian host. This extracellular armor is critical for fungal cell homeostasis and survival. Fungus-specific cell wall moieties, such as β-1,3-glucan, ar
Externí odkaz:
https://doaj.org/article/4da9c9b4bb334467bcbb87a32cd2e4e6
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Candida auris is a recently emerged multidrug-resistant fungal pathogen causing severe illness in hospitalized patients. C. auris is most closely related to a few environmental or rarely observed but cosmopolitan Candida species. However, C. auris is
Externí odkaz:
https://doaj.org/article/7994229906c040569809a58da4479672
Autor:
Arnab Pradhan, Gabriela M. Avelar, Judith M. Bain, Delma S. Childers, Daniel E. Larcombe, Mihai G. Netea, Elena Shekhova, Carol A. Munro, Gordon D. Brown, Lars P. Erwig, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT Organisms must adapt to changes in oxygen tension if they are to exploit the energetic benefits of reducing oxygen while minimizing the potentially damaging effects of oxidation. Consequently, organisms in all eukaryotic kingdoms display rob
Externí odkaz:
https://doaj.org/article/7246d978081d4c2eaaefcf2803e7a1d6
Autor:
Delma S Childers, Ingrida Raziunaite, Gabriela Mol Avelar, Joanna Mackie, Susan Budge, David Stead, Neil A R Gow, Megan D Lenardon, Elizabeth R Ballou, Donna M MacCallum, Alistair J P Brown
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005566 (2016)
Efficient carbon assimilation is critical for microbial growth and pathogenesis. The environmental yeast Saccharomyces cerevisiae is "Crabtree positive", displaying a rapid metabolic switch from the assimilation of alternative carbon sources to sugar
Externí odkaz:
https://doaj.org/article/480c42f57b65432d93a7ba882d68edff
Autor:
Joanna Mackie, Edina K Szabo, Dagmar S Urgast, Elizabeth R Ballou, Delma S Childers, Donna M MacCallum, Joerg Feldmann, Alistair J P Brown
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158683 (2016)
Nutritional immunity is a process whereby an infected host manipulates essential micronutrients to defend against an invading pathogen. We reveal a dynamic aspect of nutritional immunity during infection that involves copper assimilation. Using a com
Externí odkaz:
https://doaj.org/article/3f91aa938b784876b61d53a7304d1bb3